Clinical trials: Circumcision
HIV
Safety and Acceptability of the PrePex™ Device for Male Circumcision in Zambia
The study will measure the incidence of moderate and severe adverse events (AEs) associated with PrePex procedures among 500 men, including both procedural and post-procedure events, and all device-related incidents such as…
- Trial name
- NCT01844102
- Testing
- PrePex
- Where
- Zambia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- FHI 360
Male Circumcision, HIV Prevention
A Pivotal Study to Assess the Safety and Efficacy of The PrePex System, a Male Circumcision Device and Methodology for Rapid Scale up of Painless and Bloodless National Circumcision Programs, in Urban and Remote Rural Settings
The protocol, approved by the Rwanda National Ethical Committee, was issued to assess the safety and efficacy of the circumcision device for applying it to the national scale up of adult male circumcision in Rwanda
- Conditions
- Male Circumcision, HIV Prevention, HIV Infections
- Trial name
- NCT01150370
- Testing
- The PrePex a novel device for adult male circumcision
- Where
- Rwanda
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
HIV
Increasing Availability and Acceptability of Circumcision in Zambia
This study proposes to balance supply and demand of male circumcision through a systematic scale-up of coordinated biomedical surgical and behavioral counseling services.
- Trial name
- NCT01688167
- Testing
- MC and sexual risk reduction
- Where
- Zambia
- Volunteers
- 1,468 people, healthy volunteers welcome
- Sponsor
- University of Miami
Circumcision, Adolescents
Safety and Efficacy Study of Non-Surgical MC Device for Adolescent Male Population Including Contraindicated Subjects
A new Male Circumcision (MC) device, PrePex, has shown great promise as a way to radically shift the MC landscape. PrePex is an innovative circumcision device requiring no injected anesthesia, sutures, or sterile settings.
- Trial name
- NCT02581722
- Testing
- PrePex Device
- Where
- Rwanda
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
HIV Infections
Papuan Indigenous Model of Male Circumcision
The purpose of the study is: AIM 1: To engage Papuan community members to explore acceptability, barriers and facilitators for introducing a school-based age and culturally appropriate, comprehensive VMMC intervention to reduce…
- Trial name
- NCT06212531
- Testing
- Medical male circumcision using standard surgical technique.
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Preoperative Fasting, Perioperative Anxiety
Preoperative Fasting and Perioperative Outcomes in Children Undergoing Elective Circumcision
This prospective observational study aims to evaluate adherence to preoperative fasting guidelines and investigate the relationship between actual fasting durations, anxiety levels, and blood glucose levels in children aged 1-10…
- Conditions
- Preoperative Fasting, Perioperative Anxiety, Perioperative Hypoglycemia
- Trial name
- NCT07876583
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Burcu Ayvazoğlu
Postoperative Pain, Postsurgical Pain
Sustained Release Lidocaine for the Treatment of Postoperative Pain
In this study, the investigators are testing a new formulation of lidocaine for its suitability in managing postoperative pain after pelvic (circumcision, inguinal, scrotal), perineal (hemorrhoidectomy) or perianal (fistulotomy)…
- Trial name
- NCT05193227
- Testing
- ST-01, Control (Lidocaine Hydrochloride Injection USP Xylocaine® or Bupivacaine Hydrochloride Injection USP Marcaine®)
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Health Knowledge, Attitudes, Practice, Health Risk Behaviors
Like Father Like Son
This purpose of this study is to look at the best way to offer the Like Father Like Son + Spear \& Shield program.
- Trial name
- NCT04119414
- Testing
- Spear and Shield (S&S) Program, Like Father Like Son (LFLS) Program
- Where
- Zambia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Miami
Circumcision
Circumcision With a Novel Disposable Device in Chinese Children: a Hospital-based Randomized Controlled Trail
Circumcision, a removal of the foreskin, is performed commonly at any age in male worldwide. Globally over 25% of men are circumcised. In the Middle East, circumcision is even performed routinely in every male newborn.
- Trial name
- NCT01477593
- Testing
- circumcision with Shenghuan in Yan's method, circumcision with Shenghuan in Peng's method, conventional method with incision
- Volunteers
- 120 people
- Sponsor
- Feng Pan