Clinical trials: Cleft Lip and Palate
Cleft Lip and Palate, Maxillary Expansion
Effectiveness of Two Maxillary Expanders in Improving the Transverse Skeletal and Dental Dimensions in Patients With Cleft Lip and Palate
This randomized controlled trial is designed to compare between quadlelix appliance vs hyrax expander regrading the their effectiveness in maxillary expansion in patients with cleft.
- Trial name
- NCT04331977
- Testing
- Maxillary Expansion
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obstructive Sleep Apnea Syndrome, Cleft Lip/Palate
A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate
The study is to examine the relationship between sleep apnea and neurocognitive behaviors in children with cleft lip/palate. Describe the incidence and severity of obstructive sleep apnea in an unselected population of grade…
- Trial name
- NCT00156442
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Cleft Lip and Palate
Ultrasound Diagnosis of Cleft Lip and Palate
Cleft lips and palate are one of the most frequent congenital malformation. From 2005 to 2009, a French study, conducted by Dr Bäumler et al.
- Trial name
- FENCHU (NCT03582111)
- Testing
- Study of medical records
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cleft Lip and Palate
Challenges and Concerns Faced by Parents of Children With Cleft Lip and/or Palate
Cleft lip and/or palate (CLP) are the most common oro-facial congenital anomalies. These anomalies have an impact on feeding, speech and speech development, facial aesthetics \& oral health, all of which are factors that heavily…
- Trial name
- NCT05730946
- Testing
- Interview- based questionnaire
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Ain Shams University
Cleft Palate Children, Speech Disorders in Children
Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate
Speech therapy in children with a palate deals with two scientific challenges that will be addressed in this project. The first challenge is selecting the best speech approach for a child with a specific cleft speech…
- Conditions
- Cleft Palate Children, Speech Disorders in Children, Cleft Lip and Palate, Speech Therapy
- Trial name
- NCT06105099
- Testing
- Motor-phonetic intervention, Phonological intervention, Combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 135 people
- Sponsor
- University Ghent
Cleft Lip Palate
Quadratus Lumborum Block for Iliac Bone Harvest in Pediatric Cleft Alveolus Repair
This prospective, randomized, double-blinded controlled trial will investigate the effectiveness of a lateral quadratus lumborum (QL) block in 50 children aged 6-14 years undergoing iliac crest bone grafting for cleft alveolus…
- Trial name
- NCT07846761
- Testing
- Lateral quadratus lumborum block
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Cleft Palate, Cleft Lip and Palate
Book Sharing for Toddlers With Clefts
Children with clefts exhibit difficulty with language and literacy compared to children without clefts. However, little is known about interventions to address these difficulties in the cleft population.
- Trial name
- BOOST (NCT06338319)
- Testing
- Book-Sharing for Toddlers with Clefts (BOOST)
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Seattle Children's Hospital
Surgically Repaired Unilateral Cleft Lip and Palate
Evaluation of Arch Dimensions of Children With Surgically Repaired Unilateral Cleft Lip and Palate
The aim of the study is to assess arch dimensions among children with surgically repaired unilateral cleft lip and palate.
- Trial name
- NCT03219021
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Menna Allah Mohammed Awad
Cleft Lip and Palate
Rapid Maxillary Expansion and Protraction by Expander Differential Opening EDO in Cleft Lip and Palate Patients
maxillary expansion in cleft palate patient with expander and using face mask.
- Trial name
- NCT05009472
- Testing
- expander with deferential opening and petit face mask
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Faculty of Dental Medicine for Girls
Parenting, Alopecia
Mindful Parenting - A Single Case Experimental Design Study
Some parents of children living with a visible difference can experience heightened stress due to the associated challenges of this. Parent's views of the child's visible difference and their responses to the child are important.
- Conditions
- Parenting, Alopecia, Skin Condition, Limb Difference
- Trial name
- NCT05779527
- Testing
- Mindful Parenting Programme
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Cleft Lip, Cleft Palate
Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes
Children who are born with cleft palate need surgery in order to correct the problem. The surgery is needed because the defect allows food to leak into the nose.
- Trial name
- NCT01380171
- Where
- United States
- Volunteers
- 1,295 people
- Sponsor
- Children's Healthcare of Atlanta
Cleft Lip and/or Palate, Distraction of Bone
Tooth-borne Interdental Distraction Osteogenesis Along Arch Curvature for Wide Alveolar Clefts Reduction
This clinical study provided a modified simple and small appliance for reduction of wide alveolar clefts in cleft lip and palate patients, making the grafting procedure of better prognosis and increase its success rate.
- Trial name
- IDO (NCT07578207)
- Testing
- Tooth borne Interdental distraction appliance with mini hyrax screw
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Cleft Lip, Cleft Lip and Palate
Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate
The purpose of this study is to determine whether secondary (revision) surgery to the lip in patients with cleft lip and palate is effective in improving lip function and appearance.
- Trial name
- NCT00070811
- Testing
- Lip revision surgery
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cleft Lip and Palate
Two Methods of Lip Taping as a Presurgical Orthopedic Appliance
A randomized clinical trial to compare the effectiveness of two methods of lip taping as a presurgical orthopedic appliances on maxillary arch dimensions in infants with bilateral cleft lip and palate.
- Trial name
- NCT05796336
- Testing
- Lip taping
- Where
- Iraq
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Cleft Lip, Cleft Palate
Follow Ups of Parents With Infants With Cleft Lip and Palate
In Norway, 100-120 children are born with CLP (1.9 per 1,000 live births) each year. Parents of infants with CLP need information and support, especially with feeding immediately after birth. These needs are often not met.
- Trial name
- NCT02415361
- Testing
- Cleft lip and palate
- Where
- Norway
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cleft Palate
Sleep and Behavior in Children With Cleft Palate
The purpose of this study is to determine whether cleft palate repair increases the risk for obstructive sleep apnea in children and whether sleep apnea could explain learning and behavior difficulties that are often observed.
- Trial name
- NCT01046591
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bilateral Cleft Lip and Palate, Maxillary Expansion
Efficiency of Two Maxillary Expanders for Maxillary Arch Expansion in Bilateral Cleft Lip and Palate Patients
This randomized controlled trial is designed to compare between Fan expander with palatal springs appliance vs three-way expander regarding the their effectiveness in maxillary expansion in patients with bilateral cleft
- Trial name
- NCT07056296
- Testing
- 3D Maxillary Expansion with 3 expansion screws, 3D Maxillary Expansion using modified Fan expander with springs
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Rare Diseases, Aniridia
Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies
The cross-sectional observational clinical study related to rare eye diseases is a multi-center study in which the hypothesis is that neurokinin 1 receptor and/or substance P expression is increased in REDs associated with…
- Conditions
- Rare Diseases, Aniridia, Neurotrophic Keratopathy, Limbal Stem Cell Deficiency
- Trial name
- NCT06412718
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Cleft Lip and Palate
Cost Effectiveness in Alveolar Bone Grafting in Patients With Cleft Lip and Palate
The purpose of this trial is to evaluate if the use of Bone Morphogenic Protein(BMP)/Demineralized Bone Matrix (DBM) versus the use of autologous Iliac Crest Bone Graft (ICBG) will result in an increase in total cost…
- Trial name
- NCT04234971
- Testing
- Intervention group (DBM/BMP), Control group(autologous ICBG)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cleft Lip and/or Palate, Cleft Lip Bilateral
Conventional Versus Modified Pre-surgical Naso-Alveolar Molding Treatment in Cleft Lip and Palate Infants
The aim of this study is to evaluate and compare clinically conventional Pre-surgical Naso-Alveolar Molding (PNAM) treatment versus Modified Naso-Alveolar Molding protocol (MPNAM) in cleft lip and palate patients in terms of: 1.
- Trial name
- NCT06494098
- Testing
- Nasoalveolar Molding, Addition silicone impression
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University