Clinical trials: Clinical
Stress Regulation and Well-being in Non-clinical Contexts
The Concert Therapy for Stress Regulation in a Non-Clinical Adult Population
The Concert Therapy is a non-clinical, art based well-being intervention designed to support stress regulation through a structured, concert like experience.
- Trial name
- TCT-RCT (NCT07430631)
- Testing
- The Concert Therapy, Active Control: Relaxing Music and Quiet Rest
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Behnam Khodarahmi
Prevention of Malaria Transmission and Clinical Malaria
Dose-Escalating Study of Pfs230D1 in Combination With R21 in Matrix-M in African Adults
This is a Phase 1, individually randomized, double-blind, dose escalating study designed to evaluate the safety, tolerability, and immunogenicity of Pfs230D1 conjugate vaccines, R21 nanoparticle vaccine, or their combination…
- Trial name
- NCT06507605
- Testing
- R21, Pfs230D1-CRM197, Pfs230D1-EPA
- Where
- Mali
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Serum Institute of India Pvt. Ltd.
Spinal Cord Injury, Safety
Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase II Randomized Controlled Trial
Purpose: This clinical trial is studying an investigational cell therapy called XS228-a lab-made stem cell product designed to help repair damaged nerves in the spinal cord.
- Conditions
- Spinal Cord Injury, Safety, Efficacy, Clinical Trial
- Trial name
- NCT06974968
- Testing
- Allogeneic Human Induced Pluripotent Stem Cell (iPSC)-Derived Motor Neuron Progenitor Cells
- Where
- China
- Volunteers
- 60 people
- Sponsor
- XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.
Spinal Cord Injury, Safety
Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial
This Phase I clinical trial is designed to evaluate the safety, tolerability of XS228 ( iPSC-Derived Motor Neuron Progenitor Cells) in patients with Subacute Spinal Cord Injury
- Conditions
- Spinal Cord Injury, Safety, Clinical Trials, Efficacy
- Trial name
- NCT06976229
- Testing
- Allogeneic Human Induced Pluripotent Stem Cell (iPSC)-Derived Motor Neuron Progenitor Cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.
Clinical Characteristics and Treatment Outcomes of Malignant Tumor Cachexia, Multicenter Observational Study
A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer Cachexia
This study is a prospective, real-world observational study. The objective is to evaluate the effectiveness and safety of nanocrystalline megestrol acetate in patients with cancer cachexia in real-world settings.
- Trial name
- NCT07243379
- Testing
- Nanocrystalline Megestrol Acetate
- Where
- China
- Volunteers
- 495 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
To Validate the Clinical Performance of AI/ML Technologies in First-trimester Pregnant Participants, First Trimester Pregnancy
Clinical Performance Evaluation of the Artificial Intelligence (AI)/ Machine Learning (ML) Technologies Utilized by the Origin Medical EXAM ASSISTANT
A multicenter study will be conducted to assess the role of the AI/ML technologies of Origin Medical EXAM ASSISTANT (OMEA) in interpreting first-trimester fetal ultrasound examinations (11 weeks 0 days - 13 weeks 6 days).
- Trial name
- NCT06952439
- Testing
- Images and cines captured through the capture card (ICC)
- Where
- 15 sites in United States
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- Origin Medical Systems, Inc.
Mobility Impairment, Clinical Workflow Optimization
Deployment and Evaluation of Humanoid Robotics in Coalition-Aligned Clinical Care Settings
This clinical trial evaluates the deployment of humanoid robotics in coalition-aligned healthcare settings. The study measures biometric performance, ESG compliance, and operational impact across patient care, sanitation, and…
- Conditions
- Mobility Impairment, Clinical Workflow Optimization, Sanitation Protocol Compliance, ESG-linked Healthcare Robotics Deployment
- Trial name
- HEALTH (NCT07214896)
- Testing
- Skin Cell Dip, Stem Cell Dip, Wage Token Distribution
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Hemodialysis, Clinical Assessment
Contactless Optical Monitoring of AV Access Using the PatenSee System in Outpatient Hemodialysis Patients
This is a prospective, non-interventional, single arm, international multicenter study in which up to 120 adult participants with kidney failure requiring regular hemodialysis through arteriovenous (AV) access (AV fistula or…
- Trial name
- NCT07194395
- Testing
- PatenSee System
- Where
- 2 sites in United States, Israel
- Volunteers
- 90 people
- Sponsor
- PatenSee Ltd.
Blood Self-Collection for Clinical Diagnostic Assessments
Evaluation of Tasso+ Blood Self-Collection for Clinical Diagnostic Assessment of Various Biomarkers
This study aims to assess the effectiveness and reliability of the Tasso+ capillary blood self-collection device in the clinical diagnostic assessment of various biomarkers.
- Trial name
- NCT05852925
- Testing
- Traditional Venipuncture, Tasso+
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- American Research Labs
Clinical Characteristics and Treatment Outcomes of Malignant Tumor Cachexia, Multicenter Observational Study
Real-World Clinical Study for Malignant Tumor-Induced Cachexia
This study is a non-interventional, multicenter observational study, aiming to assess the clinical characteristics and treatment outcomes of malignant tumor cachexia.
- Trial name
- NCT07008248
- Where
- China
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Sepsis, Septicemia
A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning
In this study, the investigators will deploy a software-based clinical decision support tool (eCARTv5) into the electronic health record (EHR) workflow of multiple hospital wards.
- Conditions
- Sepsis, Septicemia, Respiratory Failure, Hemodynamic Instability
- Trial name
- NCT05893420
- Testing
- eCARTv5 clinical deterioration monitoring, Standard of care control
- Where
- 3 sites in United States
- Volunteers
- 30,000 people
- Sponsor
- AgileMD, Inc.
Clinical Pharmacology, Pharmacokinetics
Effect of Coadministration of Itraconazole on the Pharmacokinetics of CRD-740
This is a Phase 1, single-site, open-label, fixed sequence crossover study to investigate the effect of coadministration of itraconazole on the pharmacokinetics of CRD-740 in healthy male and female subjects.
- Conditions
- Clinical Pharmacology, Pharmacokinetics, Cardiovascular Diseases, Heart Failure
- Trial name
- NCT05437094
- Testing
- CRD-740, Itraconazole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cardurion Pharmaceuticals, Inc.
Participants Who Received an Allogeneic Chimeric Antigen Receptor T-Cell Product (PBCAR) in a Precision BioSciences, Inc., Clinical Study
Long-term Follow-up of Study Participants Who Received an Allogeneic Chimeric Antigen Receptor T-Cell Product in an Imugene Ltd. Clinical Study
The goal of this observational study is to collect information on the long-term safety of study participants who received an Allogeneic Chimeric Antigen Receptor (CAR) T-Cell Product in an Imugene Clinical Study.
- Trial name
- NCT05822427
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Imugene Limited
Clinical Indication for Brain MRI, Healthy Volunteers
Comparative Study of Conventional MR Images With Synthetically Reconstructed MR Images of the Brain
This study is being conducted for evaluation of 3D Synthetic MRI (SyMRI 15, 3D) for neuroimaging,
- Trial name
- NCT05425927
- Testing
- SyMRI 15 (3D)
- Where
- 6 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- SyntheticMR
Blincyto Use in Routine Clinical Practice
Observational Study of Blinatumomab
An observational study of blinatumomab safety and effectiveness, utilisation, and treatment practices.
- Trial name
- NCT03117621
- Where
- 80 sites in Austria, Czechia and 11 more
- Volunteers
- 279 people
- Sponsor
- Amgen
Clinical Competence, Medical Education
Intervention for Medical Student to Promote Cervical Cancer Screening Among Latinx Transmasculine Individuals
The team aims to test the effectiveness of an intervention to increase gender-affirming cervical cancer prevention behaviors targeted at medical students studying in Puerto Rico and Florida.
- Conditions
- Clinical Competence, Medical Education, Cervical Cancer Screening
- Trial name
- CC-Trained (NCT06844097)
- Testing
- Cervical Cancer Trans Inclusive Education (CC-TRAINED) Module, Disaster Preparedness Course
- Volunteers
- 60 people
- Sponsor
- Ponce Medical School Foundation, Inc.
Clinical Procedures Which Require Vessel Cannulations in Pediatric Patients
Novel Device for Ultrasound-guided Pediatric Vessel Cannulations
Clinical Trial to investigate whether the use of a novel device to be used in conjunction with ultrasound in pediatric vessel cannulations is superior to ultrasound-only pediatric vessel cannulations in terms of number of…
- Trial name
- NCT04039490
- Testing
- SCENERGY
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Clear Guide Medical
Clinical Pharmacology
The Mass Balance Study of LP-168 in Healthy Subjects
This study is a single-center, open-label, single-dose clinical pharmacokinetic study. The purpose of this study is to investigate the absorption characteristics, as well as to evaluate the metabolism and elimination pathways…
- Trial name
- NCT06126861
- Testing
- [14C]LP-168
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Guangzhou Lupeng Pharmaceutical Company LTD.
Infectious Disease, Neoplasms
AnovaOS Network Powered Patient Registry
The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and…
- Conditions
- Infectious Disease, Neoplasms, Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89), Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- Trial name
- NCT05013944
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Anova Enterprises, Inc
Respiratory Depression, Respiratory Failure
VitalThings Guardian Contactless Monitoring
This is a confirmatory study without any intervention. It is an uncontrolled, non-randomized and open-label study with measurements made with comparators, and it has a preset hypothesis for the primary endpoint.
- Conditions
- Respiratory Depression, Respiratory Failure, Deterioration, Clinical
- Trial name
- VINCENT (NCT06083272)
- Testing
- Vitalthings Guardian M10 fixed and M10 mobile
- Where
- Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- VitalThings