Clinical trials: Clinical Anxiety
Anxiety
Intranasal Dexmedetomidine Versus Oral Paracetamol as a Pre-anaesthetic Medication in Pediatric Age Group
Pre-operative anxiety is a major problem in children because it produces undesired results on induction and postoperative outcome. Dexmedetomidine is a highly specific alpha 2 adrenergic receptor agonist.
- Trial name
- NCT04949477
- Testing
- Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Benha University
Dental Anxiety, Pain
Comparison of Five Anesthetic Delivery Systems for Palatal Infiltration
This study is a randomized clinical trial evaluating five different anesthetic delivery systems for palatal infiltration in adults undergoing maxillary molar extraction.
- Conditions
- Dental Anxiety, Pain, Dental, Palatal Anesthesia
- Trial name
- PAL-INJECT (NCT07184879)
- Testing
- Conventional Dental Syringe, Spring-Activated Syringe (PCJ, PAROJECT™), Needle-Free Jet Injector (NFI, Comfort-in™)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sercan Küçükkurt
Anxiety, Stress
The Effect of Web Based Progressive Muscle Relaxation Exercise on Clinical Stress and Anxiety of Nursing Students
Purpose: The study was conducted to examine the effect of web-based progressive muscle relaxation exercise on the perceived stress and anxiety level of nursing students who were in clinical practice for the first time.
- Conditions
- Anxiety, Stress, Nursing Students, Relaxation Program
- Trial name
- NCT05312749
- Testing
- progressive relaxation exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anxiety, Intraoperative Hypertension
The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery
This study investigates whether television viewing or music listening can reduce pre-operative anxiety and improve surgical outcomes for patients undergoing cataract surgery.
- Conditions
- Anxiety, Intraoperative Hypertension, Cataract
- Trial name
- NCT06356324
- Testing
- Music Intervention, Television Intervention
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury
Multidimensional Sleep Health Intervention to Optimize Concussion Recovery
Following adolescent concussion, poor sleep health is common and relates to the development of persisting post-concussion symptoms, and uninjured adolescents (independent of concussion) also commonly experience sleep…
- Conditions
- Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury, Treatment, Sleep Health
- Trial name
- SCORE (NCT07082218)
- Testing
- Sleep Intervention
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Colorado, Denver
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Anxiety
A Pilot Study to Determine a Candidate Protocol for Transcranial Electrical Stimulation in the Treatment of Anxiety
The investigators examine the efficacy of two different transcranial direct current stimulation (tDCS) stimulation protocols in the treatment of anxiety in an open-label pilot study.
- Trial name
- NCT02321891
- Testing
- NeuroConn DC Stimulator Plus, tDCS
- Where
- Finland
- Volunteers
- 14 people
- Sponsor
- University of Eastern Finland
Generalized Anxiety Disorder
Phase 3 Clinical Trial of Buagafuran Capsules in the Treatment of GAD
A placebo-controlled superiority design was used to evaluate the efficacy of 60 mg/ day or 120 mg/ day of Buagafuran capsules in the treatment of GAD
- Trial name
- BGFN-2022-02 (NCT06243640)
- Testing
- Buagafuran capsules, 15mg/ capsule, Buagafuran capsules mimic, 0mg/ capsule
- Where
- China
- Volunteers
- 504 people
- Sponsor
- Beijing Union Pharmaceutical Factory Ltd
Inguinal Hernia Repair
Buccal Midazolam Versus Intranasal Dexmedetomidine Plus Oral Chloral Hydrate in Inguinal Hernia Repair
Inguinal hernia surgery is one of the most common surgical procedures in early infancy. Preoperative anxiety remains a vexing issue, and it exists in nearly 50% of pediatric patients
- Trial name
- NCT06389318
- Testing
- oral chloral hydrate,intranasal dexmedetomidine and buccal normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Obsessive-Compulsive Disorder
Acceptance and Commitment Therapy (ACT) in Groups for Obsessive Compulsive Disorder: A Clinical Trial in Brazil
The goal of this clinical trial is to learn if Acceptance and Commitment Therapy (ACT) + Exposure and Response Prevention (ERP) in Group is effective to Obsessive Compulsive Disorder (OCD) in adults.
- Trial name
- NCT06548893
- Testing
- Group acceptance and commitment therapy (ACT)
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal do Paraná
Anxiety, Depression
Probiotics and the Microbiome: Clinical Intervention Trial for Anxiety and Depression
The proposed project will investigate the effects of probiotics on anxiety and associated psychological and physiological factors in humans.
- Trial name
- NCT02035878
- Testing
- Probiotics
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Acadia University
Diabetic Peripheral Neuropathy
Effect of an Exercise Program on Clinical Aspects of People With Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy (DPN) is one of the most prevalent and debilitating complications of type 2 diabetes mellitus (DM2), especially affecting the distal region of the lower limbs.
- Trial name
- NCT07075367
- Testing
- Proximal/distal protocol, Distal protocol
- Volunteers
- 64 people
- Sponsor
- Federal University of Piaui
Depression - Major Depressive Disorder, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Is Betwixt App Effective and Acceptable?
Title Is the Betwixt application effective and acceptable in improving emotion regulation for an adult clinical population? Short title Betwixt: Effective/acceptable clinical population emotion regulation? Chief Investigator…
- Trial name
- NCT06958887
- Testing
- Betwixt app intervention
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- University of Nottingham
Children's Anxiety Levels, Children's Behavior
The Effect of Vibration Devices on Pain and Discomfort During Local Anesthesia Administration in Children
This split-mouth randomized clinical trial will be conducted at the Department of Pediatric Dentistry, King Abdulaziz University Dental Hospital (KAAUDH).
- Conditions
- Children's Anxiety Levels, Children's Behavior, Physiological Changes (Heart Rate), Obejective Pain and Discomfort
- Trial name
- NCT07384923
- Testing
- DentalVibe intraoral vibration device, Buzzy Bee® extraoral vibration device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Mental State, Reported as Depression, Anxiety or Stress
The Impact of Giving a Massage
The aim of this study is to investigate if giving a massage impacts the mental state of a massage therapist, including depression, anxiety, and stress .
- Trial name
- NCT01169480
- Testing
- Give a massage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Parker Research Institute
Anxiety Disorders, Depressive Disorders
Japan Unified Protocol Clinical Trial for Depressive and Anxiety Disorders (JUNP Study)
This study is to examine the superiority of the combined treatments of transdiagnostic cognitive-behavior therapy (Unified Protocol; UP) and Treatment-As-Usual in comparison with the waiting-list with Treatment-As-Usual in the…
- Trial name
- NCT02003261
- Testing
- Unified Protocol with Treatment As Usual, Treatment As Usual
- Where
- Japan
- Volunteers
- 104 people
- Sponsor
- National Center of Neurology and Psychiatry, Japan
Anxiety
Manual Acupuncture Using Acupuncture Needle vs Press Needle for COVID-19 Healthcare Anxiety
This study would like to compare manual acupunture treatment for anxiety in COVID Health workers population in Cipto Mangunkusumo Hospital using filiform needles and press needle.
- Trial name
- NCT04860271
- Testing
- Manual Acupuncture
- Where
- Indonesia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anxiety, Depression
Therapist-guided Internet-delivered Cognitive Behavioural Therapy
Depression and anxiety are prevalent and disabling conditions that often go untreated. Internet-delivered Cognitive Behaviour Therapy (ICBT) is a relatively new approach to treatment that is a convenient way for patients to…
- Trial name
- NCT03304392
- Testing
- Personalized ICBT, Standard ICBT
- Where
- Canada
- Volunteers
- 449 people
- Sponsor
- University of Regina
Rare Diseases
FACE for Children With Rare Diseases
Children with ultra-rare or complex rare diseases are routinely excluded from research studies because of their conditions, creating a health disparity.
- Trial name
- FACE-Rare (NCT04855734)
- Testing
- FAmily CEntered (FACE) pACP Intervention
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's National Research Institute
Psychotic Disorders, Anxiety
A Study of Dose-response Relationship and the Evidence Based Multisensory Stimulation Intervention
Design: This parallel randomized controlled trial (RCT) was conducted according to the Consolidated Standards of Reporting Trials (CONSORT).
- Conditions
- Psychotic Disorders, Anxiety, Complementary Therapies, Clinical Trial
- Trial name
- NCT05012709
- Testing
- multisensory stimulation therapy
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- Jianan Psychiatric Center, Ministry of Health and Welfare