Clinical trials: Clinical Anxiety
Dental Anxiety, Pain
Virtual Reality Distraction During Restorative Dental Treatment
This split-mouth randomized clinical trial will evaluate the effect of virtual reality (VR) distraction on pain perception, anxiety, physiological responses, and patient experience during local anaesthesia administration and…
- Trial name
- NCT07738718
- Testing
- Virtual Reality Headset, Standard Dental Treatment
- Where
- Saudi Arabia
- Volunteers
- 13 people
- Sponsor
- Qassim University
Obsessive-Compulsive Disorder
An OCD Prevention Programme for at Risk Adults
The main purpose of this randomised clinical trial is to test the efficacy of a prevention program for adult who are at risk of developing OCD, thus constituting a form of tertiary prevention.
- Trial name
- ØCD (NCT06262464)
- Testing
- Prevention
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Woman's Role, Preeclampsia
Women's Perspective on First-trimester Preeclampsia Screening
The aim of this study is to evaluate women's perception on first-trimester preeclampsia screening as it is performed currently in daily practice.
- Conditions
- Woman's Role, Preeclampsia, Screening
- Trial name
- NCT05123560
- Testing
- Anonymous online questionnaire
- Where
- Spain
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postpartum Depression, Anxiety
Yoga in the NICU for Parents Study
The purpose of this proposal is to test the efficacy of yoga as a mind and body intervention to decrease stress, anxiety, and depression in parents of critically ill neonates hospitalized in the Seattle Children's and University…
- Conditions
- Postpartum Depression, Anxiety, Depression, Stress Disorder
- Trial name
- YiN (NCT05322161)
- Testing
- yoga classes
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of chemotherapy (CT), often requiring dose reductions or treatment interruptions, which can compromise efficacy of the planned CT…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQTmicrob (NCT06799351)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Anxiety, Medication-refractory Focal-onset Epilepsy
The Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety
The purpose of this study is to evaluate the feasibility, safety, and effects on anxiety of high intensity focused ultrasound ablation (FUSA) in patients suffering from treatment-refractory focal epilepsy and anxiety.
- Trial name
- NCT05032105
- Testing
- Magnetic Resonance Imaging-guided Focused Ultrasound Ablation (MRgFUSA)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Ohio State University
Pain, Post Endodontic Pain
Pain During Infiltration Injection in Anterior Maxillary Region by Transcodent Painless Needle Tips Versus Regular Needle Tips
This randomized split-mouth controlled clinical trial will compare pain experienced during anterior maxillary infiltration anesthesia using Transcodent painless needle tips and conventional dental needle tips.
- Trial name
- NCT07703410
- Testing
- Transcodent Painless Needle Tip, Conventional Dental Needle Tip
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saidu College of Dentistry
Cancer Survivorship
Taking Time to Connect: A Study of Programs for Hispanic Mothers Diagnosed With Cancer and Their Children
This NCI-funded randomized clinical trial (RCT) will test the short-term efficacy of Conexiones, a culturally adapted cancer education program designed to help Hispanic mothers diagnosed with cancer and their children to cope…
- Trial name
- TTTC (NCT03951454)
- Testing
- Conexiones, Taking Time
- Where
- 5 sites in United States
- Volunteers
- 43 people
- Sponsor
- New Mexico State University
Generalized Anxiety Disorder
Efficacy of an Acceptance-based Group Behavioral Therapy for Generalized Anxiety Disorder.
Generalized anxiety disorder (GAD) shows the weakest treatment response among anxiety disorders. The present study aimed at examining whether an acceptance-based behavioral treatment, combining mindfulness and exposure…
- Trial name
- ABBT-GAD (NCT03930095)
- Testing
- Acceptance-based Behavior Therapy, Non-directive Supportive Therapy
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- University of Sao Paulo General Hospital
Obsessive Compulsive Disorder
Comparison of Effects Between Conventional Dose and High Dose Escitalopram on Clinical Improvement in Patients With Obsessive-compulsive Disorder
OBJECTIVE: The objective of this study is to compare the effect and safety of conventional dose (20mg) and high dose (40mg) of escitalopram in patients with obsessive-compulsive disorder (OCD).
- Trial name
- NCT00723060
- Testing
- escitalopram
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Seoul National University Hospital
Aromatherapy, Stress
The Effect of Aromatherapy Before Clinical Practice on Stress, Anxiety and Depression in Midwifery Students
This study was planned as a randomized controlled study to determine the effects of petitgrain and ylang ylang oil applied before clinical practice on stress, anxiety and depression in midwifery students.
- Conditions
- Aromatherapy, Stress, Depression
- Trial name
- NCT06193876
- Testing
- Petitgrain and ylang-ylang essential oil
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tuba Kızılkaya
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
COPD, Kinesiophobia Due to Dyspnea
Clinical Variables and Dyspnea and Fear of Movement in Chronic Obstructive Pulmonary Patients
Patients diagnosed with COPD who applied to the Pulmonary Diseases Department of Kırıkkale Yüksek İhtisas Hospital will be included in the study.
- Trial name
- NCT06442059
- Testing
- Kinesiophobia Level Due to Dyspnea
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Kırıkkale University
Social Anxiety Disorder
Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective treatment for individuals with depressive/anxiety disorders.
- Trial name
- NCT05858346
- Testing
- Transdiagnostic Behavior Therapy, Cognitive Behavioral Therapy for Social Anxiety Disorder
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- VA Office of Research and Development
Childhood Anxiety Disorder, Childhood Depression
Brief Internet-delivered Intervention for Children and Adolescents With Anxiety and Depression Symptoms
Investigators developed a brief standardized internet-delivered cognitive-behavioral program for treating anxious and depressive symptoms in children and adolescents in the context of COVID-19 pandemics in Brazil.
- Trial name
- NCT05139433
- Testing
- Telepsychotherapy, Psychoeducational Videos
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- University of Sao Paulo
Cardiovascular Risk Factor, Diabetes Mellitus, Type 2
Evaluation of a Physical Activity Referral Scheme
The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3.
- Conditions
- Cardiovascular Risk Factor, Diabetes Mellitus, Type 2, Anxiety, Depression
- Trial name
- NCT03490747
- Testing
- Physical activity referral scheme, Usual care exercise referral scheme
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Paula Watson
Dexmedetomidine, Panic Attacks
Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in Adults
Panic attacks affect 13.2% of adults globally, with acute treatments (e.g., benzodiazepines) carrying dependency risks. Dexmedetomidine, an α₂-adrenergic agonist, achieves peak plasma levels in 5-15 min via nasal delivery and may…
- Trial name
- NCT07162649
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Tongji University
Treatment Resistant Depression, Generalized Anxiety Disorder
An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay
Genomind has developed and introduced a battery of genetic tests, the Genecept Assay, which clinicians can administer to patients using a simple saliva sample technique. The present study proposes to enroll 1.
- Trial name
- COM-1 (NCT01507155)
- Testing
- Genecept Assay
- Where
- United States
- Volunteers
- 685 people
- Sponsor
- Genomind, LLC
Claustrophobia, Magnetic Resonance Imaging (MRI)
Efficacy of Immersive Entertainement Glasses in Magnetic Resonance Imaging (MRI)
Background: Claustrophobia is the most common type of specific phobia, and in the context of performing an MRI, it leads to premature completion of the test or a sedation.
- Trial name
- Claustro-VIR (NCT05304143)
- Testing
- Virtual Immersive Reality Glasses, Conventional nurse support
- Where
- Spain
- Volunteers
- 206 people
- Sponsor
- Hospital Mutua de Terrassa
OBSESSIVE COMPULSIVE DISORDER (OCD)
The Efficacy of TBCT Compared to ERP in the Treatment of OCD Patients, by the Assessment of Magnetic Resonance.
This is a sample made up of ninety-six adult individuals of both sexes to be divided into three groups: the experimental group of thirty-two patients with OCD who will be undergone Trial-Based Cognitive Therapy; the gold…
- Trial name
- NCT02656784
- Testing
- Cognitive Therapy, Behavioral Therapy
- Where
- Brazil
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do PiauÍ