Clinical trials: Clinical Anxiety
Metabolic Syndrome, Hypertension
Development and Multicenter Validation of an AI-Based Remote Photoplethysmography (rPPG) Facial Scan for Multimodal Health Assessment
The goal of this observational study is to learn if a non-contact facial scan using artificial intelligence (AI) can be used to check health status in adults living in urban areas such as Jakarta.
- Conditions
- Metabolic Syndrome, Hypertension, Diabetes (DM), Tachycardia
- Trial name
- NCT07491978
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Anxiety, Odontophobia
Pain and Placebo Analgesia. Does Extended Information About Dental Procedures Reduce Pain Induced by Dental Treatment?
Information about the effectiveness of treatment has been found to reduce pain, termed placebo analgesia. In this study it will be investigated whether this finding translates to the dental clinic.
- Trial name
- NCT02160028
- Testing
- anesthetics and extended information before dental treatment, anesthetics and standard information before dental treatment
- Where
- Norway
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Dental Anxiety
Smartphone Application in Reducing Dental Anxiety
evaluating the effectiveness of smartphone applications (Tell-Play-Do) (TPD) in reduction of preoperative anxiety in children undergoing restorative treatment, as measured by heart rate and Venham's Picture Test.
- Trial name
- NCT04719299
- Testing
- Tell-Play-Do, Tell-Show-Do
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Hams Hamed Abdelrahman
Virtual Reality, Pain
Virtual Reality vs Passive Distraction for Pain Management
Background: Outpatient pediatric orthopedic procedures such as percutaneous pins removal and sutures are considered painful and generate significant stress and anxiety in children.
- Conditions
- Virtual Reality, Pain, Pain Perception, Pain Management
- Trial name
- NCT03680625
- Testing
- Passive Distraction, Virtual Reality Distraction
- Where
- 3 sites in Canada
- Volunteers
- 188 people
- Sponsor
- St. Justine's Hospital
Specific Phobia
Quetiapine in Specific Phobia
The study hypothesis is that quetiapine XR has anxiolytic properties. The study aims to investigate the putative anxiolytic properties of quetiapine XR in patients with anxiety disorders.
- Trial name
- QUISS (NCT00872716)
- Testing
- Quetiapine XR
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Muenster
Premature Birth, Decision Making
Preemie Prep For Parents (P3): Home Antenatal Prematurity Education
The Preemie Prep for Parents (P3) mobile intervention will be tested in an outpatient population of pregnant women at risk of preterm birth and their partners.
- Conditions
- Premature Birth, Decision Making, Prenatal Care, Resuscitation
- Trial name
- NCT04093492
- Testing
- Preemie Prep for Parents (P3) Outpatient Mobile Intervention, ACOG links
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Depression, Anxiety
Mindfulness and Lifestyle Interventions for Depression and Anxiety: A Pilot Study
This is a quasi-experimental evaluation of psychoeducational course focusing on mindfulness and lifestyle changes for depression and anxiety; clients in active treatment group are compared to those in a treatment-as-usual…
- Conditions
- Depression, Anxiety, Major Depression
- Trial name
- NCT01230047
- Testing
- Psychoeducational course
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Arizona State University
Panic Disorder, Agoraphobia
Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety Disorders
Anxiety disorders are the most common mental disorders in community settings, and they are associated with significant psychological distress, functional and social impairment.
- Conditions
- Panic Disorder, Agoraphobia, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- T-CBT (NCT02811458)
- Testing
- Transdiagnostic Cognitive-Behavioral Therapy
- Where
- 3 sites in Canada
- Volunteers
- 231 people
- Sponsor
- Université de Sherbrooke
Generalized Anxiety Disorder, Social Anxiety Disorder
Attention Retraining for Anxiety Disorder Patients Resistent to Antidepressants
The objective of this project is to test the combination of active or placebo Attentional Bias Modification Treatment (ABMT) to usual treatment for anxiety disorder patients resistant to antidepressants.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT01906268
- Testing
- Attentional Bias Modification Treatment (ABMT) - Active
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Preanesthetic Medication
Impact of Preoperative Midazolam on Outcome of Elderly Patients
We aim to assess, if placebo compared to preoperative administration of midazolam in elderly patients is equal in regard to the global postoperative patient satisfaction
- Trial name
- I-PROMOTE (NCT03052660)
- Testing
- Midazolam
- Where
- 9 sites in Germany
- Volunteers
- 782 people
- Sponsor
- RWTH Aachen University
Exercise Therapy, Chronical Kidney Disease
Therapeutic Exercise Programme to Improve the Functional Capacities, Depression and Anxiety of Patients With Chronic Kidney Disease During Haemodialysis Sessions.
Therapeutic Exercise During Outpatient Hemodialysis Treatment for Patients with Chronic Kidney Disease
- Trial name
- Actyren-HD (NCT06883968)
- Testing
- Therapeutic exercise during hemodialysis session
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- University of Vic - Central University of Catalonia
Pain, Needle Phobia
Pain Perception of Needle-free System
The purpose of this study is to evaluate and compare the pain perception associated with a needle-free injection system( Comfort-In) and dental injection method in filling and pulpotomy treatments
- Conditions
- Pain, Needle Phobia, Anxiety, Dental Fear
- Trial name
- NCT04653974
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
Clinical Study of Biomarkers of Stress Resilience: Role of ELK1 and GPR56
70% of Europeans will be exposed to a potentially traumatic event (PTE). Following this experience, people are likely to develop various psychiatric disorders such as post-traumatic stress disorder (PTSD) or a major depressive…
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Disorder, Major, Anxiety Disorder
- Trial name
- GeBra-clin (NCT05488418)
- Testing
- Clinical, cognitive and biological tests
- Where
- 4 sites in France
- Volunteers
- 255 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Generalized Anxiety Disorder (GAD)
Clinical, Neurophysiological and Neuroendocrine Effects of Aerobe Exercise in Generalized Anxiety Disorder (GAD)
This study investigate the effect of high-intense aerobe exercise training (HIT) on clinical and physiological parameters (anxiety, somatisation, cortisol, alpha amylase, "mismatch negativity", loudness dependence auditory evoked…
- Trial name
- GAD_exercise (NCT02662803)
- Testing
- high-intensive aerobe exercise, low-intensive aerobe exercise
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Charite University, Berlin, Germany
Anxiety
Exploring Virtual Reality in Clinical Care - Impacts on Patient Distress, Parental Anxiety and Nurse Satisfaction
Prior experience with virtual reality (VR) in clinical care has demonstrated its potential to reduce patient anxiety and distress, particularly in pediatric settings.
- Trial name
- NCT07280910
- Testing
- Virtual Reality, Survey Responses/Parent Caregivers, Survey Responses/Nurses
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Virginia Commonwealth University
Dental Anxiety, Dental Anxiety in Children
Virtual Reality Storytelling Versus Storybook Reading for Dental Anxiety in Children
Many children feel anxious before dental treatment. This study compares two ways of helping children feel calmer while waiting for their dental visit: watching a dental story through virtual reality (VR) glasses, or listening to…
- Conditions
- Dental Anxiety, Dental Anxiety in Children, Preoperative Anxiety
- Trial name
- NCT07863661
- Testing
- Virtual Reality Storytelling, Traditional Storybook Reading
- Where
- Saudi Arabia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Sleep Disturbance, Stress
GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Wellness in Adults
The goal of this study is to evaluate the effects of different products in participants experiencing feelings of anxiety. The main question it aims to answer is: Do these products affect feelings of anxiety and related wellness…
- Conditions
- Sleep Disturbance, Stress, Feeling Anxious
- Trial name
- NCT07752823
- Testing
- Active Gut Feeling Product 1, Active Gut Feeling Product 2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Holobiome, Inc.
Anxiety Depression (Mild or Not Persistent)
Clinical Trials to Evaluate Neurophysiological and Neuropsychological Effects of a Mindfulness-based Intervention
Depression and anxiety are conditions with a high prevalence in the world population and youth are no exception. In developing countries it is reported that given the conditions of social disadvantage, anxiety and depression are…
- Trial name
- PRESENTE-IA (NCT06618339)
- Testing
- Mindfulness-based intervention
- Where
- Mexico
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Stress, Anxiety
Presence of Aquarium in the Waiting Room of a Geriatric Dental Clinic
The participants in this study will be subjected to a specific clinic waiting area ambience (1- no aquarium, 2- presence of aquarium with no fish, and 3- aquarium with fish) for their period of waiting before their intended…
- Conditions
- Stress, Anxiety, Mood
- Trial name
- NCT04630600
- Testing
- No intervention, Partially-equipped aquarium in the waiting area, Fully-equipped aquarium in the waiting area
- Where
- Switzerland
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Zurich