Clinical trials: Clinical Decision Making
Aortic Valve Stenosis
First-in-Human (FIH) Study on the Feasibility and Safety of the TaviPilot Augmented Reality Guidance Software
The trial aims to evaluate the feasibility and safety of Caranx Medical TAVIPILOT augmented reality guidance software during Transcatheter Aortic Valve Replacement Procedures.
- Trial name
- NCT07043075
- Testing
- TAVR using a guidance software
- Volunteers
- 10 people
- Sponsor
- Caranx Medical
Autoimmune Hepatitis
Quantitative Magnetic Resonance Imaging to Aid Clinical Decision Making in Autoimmune Hepatitis.
This will be a prospective, observational, cross-sectional study designed to assess how a quantitative Magnetic Resonance Imaging (MRI) scan will aid in a physicians' clinical decision making process in patients with suspected or…
- Trial name
- NCT03979053
- Testing
- Multiparametric MRI Scan
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Perspectum
Hematuria, Urothelial Carcinoma
STRATA: Safe Testing of Risk for AsymptomaTic MicrohematuriA
To evaluate the clinical utility associated with the integration of Cxbladder into the evaluation of subjects presenting with hematuria for evaluation of urothelial carcinoma (UC) without compromising detection of UC.
- Trial name
- NCT03988309
- Testing
- Cxbladder
- Where
- 12 sites in United States, Canada
- Volunteers
- 554 people
- Sponsor
- Pacific Edge Limited
Rectal Cancer, Colon Cancer
Perfusion Assessment in Laparoscopic Left Anterior Resection
The purpose of this study is to demonstrate that NIR fluorescence angiography using the PINPOINT Endoscopic Fluorescence Imaging System ("PINPOINT System" or "PINPOINT") can assess viability of colon tissue during laparoscopic…
- Conditions
- Rectal Cancer, Colon Cancer, Crohn's Disease, Polyp
- Trial name
- PILLAR II (NCT01560377)
- Testing
- PINPOINT Endoscopic Fluorescence Imaging System
- Where
- 11 sites in United States
- Volunteers
- 147 people
- Sponsor
- Novadaq Technologies ULC, now a part of Stryker
Coronary Artery Disease, Angina Pectoris
Understanding Clinician Utilization of Corus CAD (Age/Sex/Gene Expression Score - ASGES) in Clinical Decision Making
The purpose of this study is to understand the use of Corus CAD also known as Age/Sex/Gene Expression score (ASGES) in the clinical decision making process of patients who underwent the evaluation of chest pain or anginal…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- UCU-CARD (NCT02223286)
- Testing
- Corus CAD
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- CardioDx
Nonconvulsive Status Epilepticus, Seizures
Does Use of Rapid Response EEG Impact Clinical Decision Making
This study is designed as a prospective, non-randomized, observational, multicenter clinical trial. The primary aim of this study is to observe if the use of the rapid responds electroencephalography (EEG) system impacts…
- Trial name
- DECIDE (NCT03534258)
- Testing
- Ceribell Rapid Response EEG, Survey
- Where
- 5 sites in United States
- Volunteers
- 164 people
- Sponsor
- Ceribell Inc.
Advanced Solid Tumors or Hematologic Malignancies
Clinical Research Platform on Decision Making and Clinical Impact of Biomarker-Driven Precision Oncology
The retrospective cohort study INFINITY will be an instrument to analyze the current practice of precision oncology in the real-world setting.
- Trial name
- INFINITY (NCT04389541)
- Where
- 97 sites in Germany
- Volunteers
- 499 people
- Sponsor
- iOMEDICO AG
Pancreatic Cystic Lesions
A Study for the PanCystPro Assay in the Management of Pancreatic Cystic Lesions
The purpose of this research is to learn if the PanCystPro assay can help doctors in making decisions about treatment and monitoring of pancreatic cysts.
- Trial name
- PanAMP (NCT06894329)
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Amplified Sciences Inc
Cancer of Prostate
Clinical Evaluation of the 'ExoDx Prostate IntelliScore' (EPI)
The purpose of this research study is investigate a new and validated urine test which predicts the likelihood of high grade prostate cancer on an initial prostate biopsy The current protocol has two objectives; one is to further…
- Trial name
- NCT03031418
- Testing
- ExoDx Prostate Intelliscore
- Where
- 18 sites in United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Exosome Diagnostics, Inc.
Pain, Chronic Pain
A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care
The purpose of this study is to evaluate the impact of genetic testing on healthcare decisions and patient outcomes for patients suffering from pain, cardiovascular problems, Arthritis, Type II Diabetes, and/or Mental Health…
- Conditions
- Pain, Chronic Pain, Mental Disorders, Cardiovascular Diseases
- Trial name
- REVOLUTION (NCT02487888)
- Testing
- Unblinded to Genetic Testing Results, Blinded to Genetic Testing Results
- Where
- 31 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Proove Bioscience, Inc.
Coronary Artery Disease, Angina Pectoris
Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making
This retrospective study will investigate clinician behavior in diagnosing patients with possible obstructive coronary artery disease who received a Corus CAD (Age/Sex/Gene Expression score - ASGES) result compared to patients…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- CU-PCP (NCT02158754)
- Testing
- Corus CAD (ASGES)
- Where
- 9 sites in United States
- Sponsor
- CardioDx
Epilepsy
The Clinical Utility of BioEP in Diagnostic Decision Making in Epilepsy
Neuronostics plan a prospective multisite trial to determine the clinical utility of BioEP in the context of diagnostic decision making.
- Trial name
- CITADEL (NCT06097195)
- Testing
- BioEP
- Where
- 2 sites in United Kingdom
- Volunteers
- 559 people
- Sponsor
- Neuronostics Ltd
Cancer, Neoplasm Metastasis
FoundationOne™ Test Registry Study
This study is a prospective, multicenter, observational study to characterize utilization patterns of the FoundationOne™ test by oncologists under conditions of routine clinical practice in the US.
- Conditions
- Cancer, Neoplasm Metastasis, Tumor
- Trial name
- FMI Registry (NCT01851213)
- Where
- United States
- Volunteers
- 510 people
- Sponsor
- Foundation Medicine
Palatal Neoplasms, Lip Neoplasm
Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-Making
Objectives Validate the OncAlert® RAPID Test by demonstrating that NPV > (1 -prevalence). Evaluate the independent and associated contribution of readily available clinical variables including age, race, gender, HPV status…
- Conditions
- Palatal Neoplasms, Lip Neoplasm, Gingival Neoplasms, Leukoplakia, Oral
- Trial name
- NCT03239834
- Testing
- OncAlert
- Where
- 26 sites in United States
- Volunteers
- 893 people
- Sponsor
- Vigilant Biosciences, Inc.
Infectious Diseases, Immunocompromised Host
Metagenomic Sequencing Across the Infectious Disease Risk and Care Continuum
The AXIS Network is a prospective, multicenter observational registry designed to generate real-world evidence on the use of metagenomic sequencing in clinical practice across a broad range of patient populations, infectious…
- Conditions
- Infectious Diseases, Immunocompromised Host, Opportunistic Infections
- Trial name
- AXIS (NCT07825714)
- Volunteers
- 10,000 people
- Sponsor
- Karius, Inc.
Coronary Artery Diseases, Multivessel Coronary Artery Disease
SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease
The SYNTAX III Revolution trial is a randomized diagnostic research study that investigates the use of CT scan and angiogram of the heart to help doctors decide which method is the best to improve blood supply to the heart in…
- Conditions
- Coronary Artery Diseases, Multivessel Coronary Artery Disease, Heart Diseases, Cardiovascular Diseases
- Trial name
- SYNTAX III (NCT02813473)
- Testing
- Coronary Angiography, Computed Tomography (CT) scan
- Where
- 6 sites in Belgium, France and 3 more
- Volunteers
- 223 people
- Sponsor
- ECRI bv
Kidney Transplantation
Evaluation of Immunobiogram® as a Tool in Adjustment of Immunosuppressant Therapy for Renal Transplant
The trial is an observational, multi-center study to determine if a new blood test (Immunobiogram®) done after renal transplant can help predict how well the immune system is working and responding to a new kidney.
- Trial name
- TRANSBIO (NCT03562845)
- Testing
- NA-Observational only
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Biohope Scientific Solutions for Human Health, S.L.
Coronary Artery Disease, Acute Coronary Syndrome
INSIGHTFUL-FFR Clinical Trial
Recently, a new device for measuring physiological lesion severity, the pressure microcatheter, was introduced. The pressure microcatheter provides similar information to the conventional measurement technique but differs as it…
- Trial name
- NCT05437900
- Testing
- Pressure Microcatheter guided strategy - PIOS MC, Pressure Wire guided strategy - PIOS - PW, Pressure Microcatheter guided strategy - Standard of care
- Where
- 29 sites in Belgium, China and 6 more
- Volunteers
- 2,500 people
- Sponsor
- CoreAalst BV
Diffuse Large B Cell Lymphoma, Follicular Lymphoma
Use of a Patient Preferences Shared Decision-Making Encounter Tool in Clinical Practice for Patients With DLBCL and FL
The goal of this project is to test the feasibility of a Patient Preferences in Shared Decision-Making encounter tool (PPSDM) in the clinical context of Diffuse Large B-Cell Lymphoma (DLBCL) and Follicular Lymphoma (FL).
- Trial name
- NCT04160442
- Testing
- Carevive CarePlanning System
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Carevive Systems, Inc.