Clinical trials: Clinical Decision Support
Simulation
Mobile Application as a Clinical Decision Support Tool for Neonatal Resuscitation in the Delivery Room
The need for neonatal cardiopulmonary resuscitation in the delivery room is rare with less than 1% of newborns requiring advanced resuscitation.
- Trial name
- MAXnéonat (NCT05613530)
- Testing
- MAX NEONAT, standard of care
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Otitis Media
Improving Otitis Media Care With Clinical Decision Support
This protocol will prospectively develop a new electronic health record (EHR)-based health information technology (IT) intervention that a) summarizes Otitis Media (OM) care into clinically meaningful episodes-of-care, b)…
- Trial name
- OMHIT (NCT00581711)
- Testing
- 3-Part Intervention, 4-Part Intervention, 1-part intervention
- Where
- United States
- Volunteers
- 55,779 people
- Sponsor
- Children's Hospital of Philadelphia
Diarrhea Infectious, Algorithms
The Utility and Feasibility of Accessible Diarrhea Etiology Prediction Tool (ADEPT) in an Informal Healthcare Setting
Diarrheal disease remains a leading cause of morbidity and mortality for children under 5 globally. Accepted best practice for managing diarrhea in the absence of blood or suspicion of cholera is rehydration, however in resource…
- Conditions
- Diarrhea Infectious, Algorithms, Decision Support Systems, Clinical, Clinical Decision-making
- Trial name
- NCT07538531
- Testing
- Diagnostic test: Accessible Diarrhea Etiology Prediction Tool (ADEPT)
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- Daniel Leung
Child Health
Dynamic CDSA to Manage Sick Children in Rwanda
This study aims to reduce morbidity and mortality among children and mitigate antimicrobial resistance using a novel clinical decision support algorithm, enhanced with point-of-care technologies to help health workers in primary…
- Trial name
- DYNAMIC-RW (NCT05108831)
- Testing
- ePOCT+
- Where
- 39 sites in Rwanda
- Volunteers
- 85,212 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Fall, Congestive Heart Failure
Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase
Polypharmacy is common among older adults in the United States and is associated with harms such as adverse drug reactions and higher costs of care.
- Conditions
- Fall, Congestive Heart Failure, Chronic Kidney Failure, Adverse Drug Event
- Trial name
- NCT03791580
- Testing
- Commitment nudge, Justification nudge
- Where
- United States
- Sponsor
- RAND
Adverse Drug Reactions, Clinical Decision Support
Multi-Agent Collaborative ADR Prediction With Human-Machine Decision Comparison
This study develops a multi-agent collaborative prediction model to forecast adverse drug reactions using real-world clinical medical records.
- Trial name
- NCT07808866
- Testing
- Retrospective medical record data analysis only, no clinical intervention
- Where
- 2 sites in China
- Volunteers
- 20,000 people
- Sponsor
- Peking University Third Hospital
Cirrhosis, Decision Support Systems, Clinical
CirrhosisRx CDS System
The aim of the study is to compare the effect of CirrhosisRx, a novel clinical decision support (CDS) system for inpatient cirrhosis care, versus "usual care" on adherence to national quality measures and clinical outcomes for…
- Trial name
- NCT05967273
- Testing
- CirrhosisRx CDS
- Where
- United States
- Volunteers
- 2,106 people
- Sponsor
- University of California, San Francisco
Pneumonia
ePneumonia: Development of an Electronic Clinical Decision Support System for Community-Onset Pneumonia
The investigators plan to further develop a prototype, evidence-based, electronic clinical decision support system (CDSS) for pneumonia care (ePneumonia) with interoperability across Electronic Health Records in order to improve…
- Trial name
- NCT03358342
- Testing
- ePneumonia CDS
- Where
- 17 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Intermountain Health Care, Inc.
Legal Rights, Medicolegal Aspects
Computer-Supported Management of Medical-Legal Issues Impacting Child Health
The investigators hypothesize that by adding a patient screening and physician alerting module to a computer-based decision support system, the investigators can improve the detection and management of legal issues that may…
- Trial name
- CHICA-MLP (NCT01800669)
- Testing
- CHICA MLP Module, CHICA without the MLP module
- Where
- United States
- Volunteers
- 582 people
- Sponsor
- Indiana University
Cardiopulmonary Exercise Test Interpretation
AI-Assisted Anaerobic Threshold Interpretation in Cardiopulmonary Exercise Testing
This prospective randomized two-period crossover reader study will evaluate whether assistance from a frozen artificial intelligence model improves physicians' interpretation of the anaerobic threshold (AT) in cardiopulmonary…
- Trial name
- PACE-Reader (NCT07833137)
- Testing
- AI-Assisted Anaerobic Threshold Interpretation, Unassisted Cardiopulmonary Exercise Test Interpretation
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Depression, Panic Disorder
Evaluating Clinical Routines for ICBT
The overall aim of this study is to test the clinical benefits of an AI-based decision support tool (DST) and to evaluate how the DST affects therapists and their patients with depression, social anxiety, or panic disorder during…
- Conditions
- Depression, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT05321628
- Testing
- Internet-based Cognitive Behavioural Therapy (iCBT) with Decision Support Tool, Internet-based Cognitive Behavioural Therapy (iCBT)
- Where
- Sweden
- Volunteers
- 401 people
- Sponsor
- Karolinska Institutet
Chronic Heart Failure (CHF)
Assessment of the Impact of Clinical Decision Support Systems Included in Electronic Health Records
A non--interventional study to assess the impact of clinical decision support systems included in electronic health records on compliance with guidelines, including routing of patients with CHF, follow-up care, prescription and…
- Trial name
- NCT06248658
- Where
- Russia
- Volunteers
- 66,166 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Chronic Kidney Disease
A Risk Based Approach to Improving Chronic Kidney Disease Management
Aim 1: To assess whether quality of care for stage 3 chronic kidney disease can be substantially improved over 18 months by: Point of care electronic alerts to primary care physicians recommending risk-appropriate care, and…
- Trial name
- NCT01203813
- Testing
- Electronic Decision Support
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Brigham and Women's Hospital
Type 1 Diabetes
Study to Assess the Metabolic Impact of IRTA© and Patients Satisfaction in Type 1 Diabetic Patients, Treated by Either Insulin Pump or Multiple Daily Insulin Injections, and Using Freestyle Libre®, a Real-time Continuous Glucose Monitoring
A prospective monocentric " before and after " study, ruled in 2 periods of 3 months : during the first period, the patient will adjust insulin treatment as usual, during the second period, the patient will adjust insulin…
- Trial name
- IRTA (NCT04211220)
- Testing
- A decision support software
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Rennes University Hospital
Mental Disorders
Enhanced Medication Reconciliation For Serious Mental Illness
The purpose of this study is to evaluate the clinical utility of a decision support tool, the Patient Medication Profile(TM), developed by Sano Informed Prescribing on medication reconciliation and identification of drug-related…
- Trial name
- NCT03169868
- Testing
- Sano Patient Medication Profile
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Precera Bioscience, Inc.
Perioperative Risk Assessment
Frailty Assessment Reveals Cognitive Differences in ASA Classification: Anesthesiologists vs Large Language Models
The American Society of Anesthesiologists (ASA) Physical Status Classification System is widely used to assess perioperative risk, but it does not explicitly include frailty as a standardized variable.
- Trial name
- ASA-AI (NCT07399938)
- Testing
- Observational Assessment Only
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Opioid Use Disorder, Clinical Decision Support
Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 2
This study is stage 2, round 2 of a larger study which refines and optimizes the EMBED clinical decision support (CDS); see NCT03658642 to increase number of ED physicians following standard of care for the administration of…
- Trial name
- NCT07602218
- Testing
- Refined EMBED CDS, Provider alert to order consultation with addiction counselor
- Where
- 3 sites in United States
- Volunteers
- 379 people
- Sponsor
- Yale University
Dyslipidemia, Coronary Artery Disease
Guideline Adherence in Dyslipidemia With Clinical Decision Support
Objective: To validate the performance of the developed clinical decision support system (CDSS) for participants with lipid metabolism disorders based on a decision tree algorithm.
- Conditions
- Dyslipidemia, Coronary Artery Disease, Atherosclerosis of Major Arteries, Cardiovascular Risk
- Trial name
- NCT07412457
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Decision Support Systems, Clinical, Heart Failure
Decision Support for Heart Failure Prescribing
Clinical decision support (CDS) tools can 'nudge' clinicians to make the best decisions easy. Although required by "meaningful use" regulations, more than 40% of CDS lead to no change and the remaining lead to improvements that…
- Trial name
- NCT06293794
- Testing
- Personalized Clinical Decision Support (CDS), Traditional Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity & Overweight
WeDosify Real World Evidence (RWE) Study: Personalized Semaglutide Dosing in U.S. Adults
This research study is studying WeDosify, an interactive web-based Clinical Decision Support tool that assists healthcare professionals in managing adults with excess weight or obesity using a Glucagon-like peptide-1 (GLP-1) drug…
- Trial name
- NCT07216651
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Closed Loop Medicine