Clinical trials: Clinical Decision-Making, open to volunteers
Children With Medical Complexity (CMC), Multiple Chronic Conditions
Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis
The goal of this pilot hybrid type I efficacy/implementation trial is to assess a newly developed decision support tool patients, parents, and providers to use during surgical treatment decision making for neuromuscular scoliosis…
- Conditions
- Children With Medical Complexity (CMC), Multiple Chronic Conditions, Neuromuscular Scoliosis, Shared Decision Making
- Trial name
- NCT07167927
- Testing
- Decision support tool
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Utah
Critical Illness, Pain
Pervasive Sensing and AI in Intelligent ICU
Important information related to the visual assessment of patients, such as facial expressions, head and extremity movements, posture, and mobility are captured sporadically by overburdened nurses, or are not captured at all.
- Conditions
- Critical Illness, Pain, Delirium, Confusion
- Trial name
- NCT05127265
- Testing
- Video Monitoring, Accelerometer Monitoring, Noise Level Monitoring
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Florida
Rheumatoid Arthritis
GenAI-Assisted Rheumatoid Arthritis Bone Erosion Risk Assessment and DMARD Selection
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive joint damage and bone erosion. Accurate assessment of RA bone erosion risk (RABER) and appropriate disease-modifying antirheumatic drug…
- Trial name
- RABER (NCT07914907)
- Testing
- GenAI-Assisted Clinical Decision Support for RABER Assessment and DMARD Selection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Prostate Cancer
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis
The shortcoming of the pre-biopsy prostate MRI approach is the recommendation to biopsy all men post-MRI even if there is no lesion seen in MRI, ie. risk of PCa is very low.
- Trial name
- multiIMPROD2 (NCT04287088)
- Testing
- A shared decision making
- Where
- 4 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Head and Neck Neoplasms
Feasibility Testing a Decision-support Intervention for Clinical Trials
A decision-support intervention are developed for a Danish nationwide randomised controlled trial (RCT) among patients with laryngeal and pharyngeal cancer referred to curative intended radiotherapy.
- Trial name
- NCT06291610
- Testing
- Clinical trial decision support intervention
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Cancer
Implementing REmote SymPtom mOnitoring and maNagement (RESPONd)
The goal of this study is to understand if the implementation of a remote symptom monitoring and management program improves outcomes.
- Trial name
- RESPONd (NCT07024329)
- Testing
- Remote Symptom Monitoring and Management, Clinic Team Huddle
- Where
- 4 sites in Canada
- Volunteers
- 1,055 people
- Sponsor
- University of Calgary
Rectal Cancer
Implementation of a Tumor Response Assessment Program Integrating the Shared Medical Decision Into the Organ Preservation Strategy for Rectal Cancer Patients
The adoption of total mesorectal excision (TME) has standardized rectal cancer surgery and improved oncological outcomes. In locally advanced rectal cancer, neoadjuvant radio chemotherapy (NACRT) has further improved oncological…
- Trial name
- EVAREC (NCT06740357)
- Testing
- Tumor response monitoring program, Standard evaluation of tumor response, Shared decision-making
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pancreatic Cancer, Diagnose Disease
AI-Powered Precision Decision-Making for Pancreatic Diseases
This multicenter clinical trial evaluates an artificial intelligence (AI) system designed to assist in the diagnosis and management of pancreatic diseases.
- Conditions
- Pancreatic Cancer, Diagnose Disease, IPMN, Pancreatic, Pancreatic Cystic Lesions
- Trial name
- NCT07439757
- Testing
- Diagnosis by Artificial Intelligence model
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Multiple System Atrophy
Medical Decision Making in Multiple System Atrophy
The goal of this clinical study is to evaluate the effects of a personalized symptomatic treatment plan integrated with monthly telemedicine and mobile palliative care interventions on a population of individuals diagnosed with…
- Trial name
- MeDeMSA (NCT06072105)
- Testing
- Telemedicine visits, Multidisciplinary, personalized symptomatic treatment
- Where
- Austria
- Volunteers
- 92 people
- Sponsor
- Medical University Innsbruck
Ocular Diseases
Ophthalmic AI-Assisted Medical Decision-Making
This is a multi-center, prospective clinical study designed to evaluate the application and effectiveness of an AI-assisted medical decision support system, leveraging multimodal data fusion, in ophthalmic clinical practice.
- Trial name
- NCT06755060
- Testing
- AI-associated strategy
- Where
- 5 sites in China, Macau
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Coronary Artery Disease, Acute Coronary Syndrome
INSIGHTFUL-FFR Clinical Trial
Recently, a new device for measuring physiological lesion severity, the pressure microcatheter, was introduced. The pressure microcatheter provides similar information to the conventional measurement technique but differs as it…
- Trial name
- NCT05437900
- Testing
- Pressure Microcatheter guided strategy - PIOS MC, Pressure Wire guided strategy - PIOS - PW, Pressure Microcatheter guided strategy - Standard of care
- Where
- 29 sites in Belgium, China and 6 more
- Volunteers
- 2,500 people
- Sponsor
- CoreAalst BV
Diagnostic Decision Making
Integrating AI Predictions With Clinician Expertise
Optimizing the interaction between the human and the machine is a major topic when deploying artificial intelligence (AI) at the bedside.
- Trial name
- NCT07457840
- Testing
- Bayesian-Updated Post-Test Probability, Standard AI Predicted Probability, Uncertainty Quantification (95% Confidence Interval)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Femoracetabular Impingement
Clinical Decision-Making in FAIS
Femoroacetabular impingement syndrome is increasingly recognized as a contributor to cartilage injury and early hip osteoarthritis.
- Trial name
- CDM-FAIS (NCT07536295)
- Testing
- Functional lateral x-ray scans, Multi-echo Fast Field Echo (mFFE) MRI, Markerless 3D motion capture
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ovarian Neoplasms, Uterine Neoplasms
Evaluation of Interactions and Group Processes in Multidisciplinary Tumor Boards in Gynecologic Oncology
Study Title Group Dynamics Evaluation in Gynecologic Multidisciplinary Tumor Boards - GOLD Study Background and Rationale Multidisciplinary Tumor Boards are central to complex oncologic decision-making.
- Trial name
- GOLD (NCT07645716)
- Testing
- Online Survey Assessment of Tumor Board Group Dynamics
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Decision-Making, Patient Care
Inflammation and Medical Provider Attitudes, Cognition, and Treatment Decisions Study
This is a randomized, double-blind clinical trial involving emergency medicine and internal medicine healthcare providers as participants.
- Conditions
- Decision-Making, Patient Care, Treatment Decisions
- Trial name
- IMPACT (NCT07842367)
- Testing
- Influenza vaccine
- Where
- 3 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Thyroid Gland Medullary Carcinoma
Patient Decision Aid in Supporting Decision-Making About When to Start or Stop New Drugs, Join Clinical Trials, or Continue Active Surveillance in Patients With Medullary Thyroid Cancer and Their Caregivers
This trial develops and studies how well a patient decision aid works in supporting decision-making about when to start or stop new drugs, join clinical trials, or continue active cancer monitoring for patients with medullary…
- Trial name
- NCT03892993
- Testing
- Decision Aid, Questionnaire Administration
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Juvenile Idiopathic Arthritis
Personalized Estimates of Response and Severity Outcomes in Newly-diagnosed JIA
The PERSON-JIA Trial is a cluster-randomized trial testing the use of Shared Decision Making (SDM) with families for treatment of children with arthritis.
- Trial name
- PERSON-JIA (NCT05310799)
- Testing
- Shared Decision Making (SDM)
- Where
- Canada
- Volunteers
- 842 people
- Sponsor
- University of British Columbia
Diagnosis, Clinical Decision-making
Reasoning Enrichment With Feedback From IA in NEphrology Trial
The goal of this clinical trial is to learn how artificial intelligence (AI) may help doctors make diagnoses in kidney medicine.
- Conditions
- Diagnosis, Clinical Decision-making, Artificial Intelligence (AI) in Diagnosis, Decision Support Systems, Clinical
- Trial name
- REFINe (NCT07352475)
- Testing
- AI suggestion
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Primary Health Care, Lower Respiratory Tract Infection
CRP and Lung Ultrasound in Respiratory Evaluation
Lower respiratory tract infections (LRTIs) are one of the most common reasons for consultation in Primary Care centres. Differentiating between viral and bacterial aetiologies can be challenging, leading to inappropriate…
- Trial name
- PLURE (NCT06294899)
- Testing
- Lung ultrasound, C-Reactive Protein Test
- Volunteers
- 202 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Last Year Medical Student
Use of Cognitive Aid Methods in the Management of Status Epilepticus
This study aims to evaluate whether cognitive aids improve the management performance of sixth-year Emergency Medicine interns during simulated status epilepticus scenarios.
- Trial name
- NCT07603843
- Testing
- Management of status epilepticus with paper cognitive aids, Management of status epilepticus with digital cognitive aids, Management of status epilepticus with no cognitive aid
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ankara University