Clinical trials: Clinical Decision-Making
Ocular Diseases
Ophthalmic AI-Assisted Medical Decision-Making
This is a multi-center, prospective clinical study designed to evaluate the application and effectiveness of an AI-assisted medical decision support system, leveraging multimodal data fusion, in ophthalmic clinical practice.
- Trial name
- NCT06755060
- Testing
- AI-associated strategy
- Where
- 5 sites in China, Macau
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Clinical Decision-Making and Virtual Reality Exercise
Degenerative lumbar spine disease (DLSD) is common in elderly individuals and can result in pain, muscle weakness, and paresthesia.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
- Trial name
- NCT05375201
- Testing
- VR skateboarding training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Carpal Tunnel Syndrome
Bilateral vs Unilateral CTR
Carpal tunnel release is a well accepted treatment for median nerve compression at the wrist. With a prevalence of 50 per 1000, it is the most common compressive neuropathy.
- Trial name
- NCT01961011
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Gastric Cancer Stage III
Using ctDNA to Guide Treatment Decisions for Stage III Gastric Cancer
The goal of this randomized, controlled phase III clinical trial is to evaluate whether combining Tislelizumab with standard SOX chemotherapy improves disease-free survival (DFS) compared to chemotherapy alone in patients with…
- Trial name
- NCT06939439
- Testing
- Tislelizumab + SOX Chemotherapy, SOX Chemotherapy
- Where
- China
- Volunteers
- 416 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Early Detection of Cancer
Understanding Information Preferences, Risk Perceptions, and Tradeoffs When Making Decisions About Multi-cancer Early Detection Tests
The goal of this clinical trial is to learn what people's informational preferences and risk perceptions are in regards to the use of multi-cancer early detection (MCED) tests.
- Trial name
- NCT07793539
- Testing
- Test Performance Information: High Detail, Test Performance Information: Low Detail, Diagnostic Workup Information: High Detail
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Trustees of Dartmouth College
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
The researchers are aimed to investigate the dynamic evolution of indeterminate pulmonary nodules by a long-term follow-up of patients with different characteristics.
- Trial name
- DEPICT (NCT04857333)
- Testing
- CT scan, Antibiotics, Surgical Resection
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- GuiBin Qiao
Anxiety Disorders, Depressive Disorder
Testing Psychosocial Treatment Planning Methods for Youth Anxiety and Depression
Youth depression and anxiety represent a serious public health concern, with affected youth often experiencing social, familial, and academic impairment.
- Trial name
- NCT03610373
- Testing
- Modular Approach to Therapy for Children (MATCH)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Cervical Cancer, HPV DNA
Postoperative ctHPV-DNA for Recurrence Prediction and Adjuvant Treatment Decision-Making in Cervical Cancer
This prospective observational study will evaluate whether changes in circulating tumor human papillomavirus DNA (ctHPV-DNA) after radical surgery can help predict the risk of recurrence in patients with HPV-associated cervical…
- Trial name
- NCT07782697
- Where
- China
- Volunteers
- 580 people
- Sponsor
- Anhui Provincial Hospital
Knee Osteoarthritis
Shared Decision Making and How It Impacts the Patient Understanding
Shared Decision Making (SDM) supports patient centered care and improves patient outcomes and satisfaction. Movement is Life (MIL) created an innovative SDM tool to provide a personalized framework for discussion of the projected…
- Trial name
- NCT04011488
- Testing
- Shared Decision Making Tool
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Hospital for Special Surgery, New York
Anxiety, Depression
POST Facilitation for Community Dwelling Older Adults (POST-RCT)
We propose to study the effects of Physician Orders for Scope of Treatment (POST) Facilitation in a randomized controlled trial in a population of community dwelling older adults who qualify for POLST facilitation, including…
- Conditions
- Anxiety, Depression, Post Traumatic Stress Disorder, Satisfaction
- Trial name
- POST-RCT (NCT04070183)
- Testing
- POST Facilitation, Home Safety Evaluation
- Where
- 3 sites in United States
- Volunteers
- 389 people
- Sponsor
- Indiana University
Coronary Artery Diseases, Multivessel Coronary Artery Disease
SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease
The SYNTAX III Revolution trial is a randomized diagnostic research study that investigates the use of CT scan and angiogram of the heart to help doctors decide which method is the best to improve blood supply to the heart in…
- Conditions
- Coronary Artery Diseases, Multivessel Coronary Artery Disease, Heart Diseases, Cardiovascular Diseases
- Trial name
- SYNTAX III (NCT02813473)
- Testing
- Coronary Angiography, Computed Tomography (CT) scan
- Where
- 6 sites in Belgium, France and 3 more
- Volunteers
- 223 people
- Sponsor
- ECRI bv
Metastatic Colorectal Cancer
Decision-making of ctDNA in Patients With mCRC After Failure of First-line Treatment Containing Cetuximab - a Single-center, Phase II Clinical Study
This study aimis at detecting the genomic changes of ctDNA in patients of RAS and BRAF wild-type mCRC, who failed after first line treatment containing cetuximab.
- Trial name
- NCT04831528
- Testing
- Cetuximab Ab; Bevacizumab; Vermofenib + cetuximab;Trastuzumab+lapatinib or trastuzumab+pertuzumab; others
- Volunteers
- 100 people
- Sponsor
- Fudan University
Phlebitis, Clinical Decision-Making in Nursing
Simulation and Video Training for Phlebitis Recognition and Clinical Decision-Making in Nursing Students
Peripheral intravenous catheters (PIVCs) are widely used for vascular access and represent one of the most common invasive procedures in hospitalized patients.
- Conditions
- Phlebitis, Clinical Decision-Making in Nursing, Learning Satisfaction and Self-confidence, Standardized Patient
- Trial name
- NCT07512986
- Testing
- Standardized Patient Simulation, Video-Based Training
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Selçuk Görücü
Education
RCT of Intensive, Brief, and Control Indigenous Cultural Safety Training Interventions for Health Care Providers
Despite Canada's relative global affluence, striking Indigenous/non-Indigenous health disparities persist. Following the release of the Truth and Reconciliation Commission of Canada's Final Report, and the publication of the…
- Trial name
- NCT05890144
- Testing
- Big Canoe, Little Canoe, Control
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV Infections, Acquired Immunodeficiency Syndrome
Decision-Making of Hispanics and African-Americans With HIV/AIDS Participating in Clinical Trials
This study will use focus groups and in-depth individual interviews to explore factors that influence the decision of Hispanics and African-Americans with HIV/AIDS to participate in a research study.
- Trial name
- NCT00394004
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients
ADLIFE is a EU-funded project developing innovative digital health solutions to support healthcare planning and care delivery for patients with advanced chronic conditions (chronic obstructive pulmonary disease and/or heart…
- Conditions
- Heart Failure NYHA Class III, Heart Failure NYHA Class IV, Chronic Obstructive Pulmonary Disease Severe
- Trial name
- ADLIFE (NCT05575336)
- Testing
- ADLIFE intervention
- Where
- 7 sites in Denmark, Germany and 3 more
- Volunteers
- 185 people
- Sponsor
- Biosistemak Institute for Health Systems Research
Renal Transplant Recipients, Non-functioning Pituitary Adenoma
Implementing eHealth Interventions Into Regular Clinical Practice
The purpose with this study is to test a digital patient-provider communication tool for symptom and needs management among patients with chronic health conditions.
- Trial name
- InvolveMe (NCT04218721)
- Testing
- InvolveMe
- Where
- Norway
- Volunteers
- 23 people
- Sponsor
- Oslo University Hospital
Digital Escape Room, Gamification
Effect of the MERCI Model in Gamified Disaster Midwifery Education
Midwives play important societal roles during the post-crisis transition and recovery phase. Specific guidelines regarding the roles and responsibilities of midwives, who constitute a significant majority among healthcare…
- Conditions
- Digital Escape Room, Gamification, Disaster, Midwifery Education
- Trial name
- NCT07090642
- Testing
- Gamified Disaster Midwifery Training (MERCI Model)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Clinical Decision Making, Tooth Extraction
On Adequacy of Referrals to Oral and Maxillofacial Surgery
Currently, an ongoing generational shift of the dental community in Sweden originates from an increased number of retiring dentists.
- Conditions
- Clinical Decision Making, Tooth Extraction, Referral and Consultation, Surgery, Oral
- Trial name
- NCT05845437
- Where
- Sweden
- Volunteers
- 624 people
- Sponsor
- Region Skane
Pain, Chronic Pain
A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care
The purpose of this study is to evaluate the impact of genetic testing on healthcare decisions and patient outcomes for patients suffering from pain, cardiovascular problems, Arthritis, Type II Diabetes, and/or Mental Health…
- Conditions
- Pain, Chronic Pain, Mental Disorders, Cardiovascular Diseases
- Trial name
- REVOLUTION (NCT02487888)
- Testing
- Unblinded to Genetic Testing Results, Blinded to Genetic Testing Results
- Where
- 31 sites in United States
- Volunteers
- 100,000 people
- Sponsor
- Proove Bioscience, Inc.