Clinical trials: Clinical Efficacy
Pain, Neck, Pain, Joint
The Effectiveness of Kinesio Taping in Violin Players
This study aimed to investigate the effectiveness of Kinesio taping (KT) on playing-related pain, upper extremity and hand function, grip and pinch strength in violin players.
- Conditions
- Pain, Neck, Pain, Joint, Pain, Shoulder, Occupational Diseases
- Trial name
- NCT05019781
- Testing
- Therapeutic tape
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Istanbul University - Cerrahpasa
AML (Acute Myelogenous Leukemia), Allogeneic Hematopoietic Stem Cell Transplantation Recipient
Efficacy and Safety of the CloB2M (Clofarabine Combined With Busulfan and Melphalan) Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation for Adult Patients With Acute Myeloid Leukemia in First Complete Remission
This is a single-center, prospective, exploratory clinical study. It plans to enroll 30 adult patients with acute myeloid leukemia (AML) who have achieved first complete remission (CR1) after induction therapy and meet the…
- Trial name
- NCT07644481
- Testing
- CloB2M (Clofarabine Combined With Busulfan and Melphalan) Conditioning Regimen
- Volunteers
- 30 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic Lower Limb Cocognitive Ortho-prosthesis Plus Plus, 1st Clinical Study (CLs++)
The aim of the study is to assess the efficacy and the usability of the cyberlegs ++ ortho prosthesis to improve the mobility and the quality of life in transfemoral amputees .
- Trial name
- NCT03376919
- Testing
- CLs++ gait training
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Deep Vein Thrombosis (DVT)
Clinical Trial of Thrombectomy Systems
This study plans to enroll 167 subjects. Subject enrollment and treatment details will be documented, and follow-up assessments will be conducted at screening, on the procedure day, before discharge, and at 1, 3, and 6 months…
- Trial name
- NCT07749820
- Testing
- Peripheral thrombectomy system
- Where
- China
- Volunteers
- 167 people
- Sponsor
- BrosMed Medical Co., Ltd
Low Back Pain
Efficacy of DBM Fasciatherapy for Patients Suffering From Chronic Low Back Pain
Low back pain (LBP) is pain localized below the costal margin and above the inferior gluteal folds. It may be associated with radiculalgia.
- Trial name
- NCT04812678
- Testing
- Fasciatherapy, Physiotherapy
- Where
- France
- Volunteers
- 188 people
- Sponsor
- FasciaFrance
Asthma
Flutiform in Treatment of Patients With Asthma in Daily Clinical Practice.
The objective of the study is to evaluate the effect of frequency of use with a spacer on asthma control in Dutch patients with asthma during their daily clinical practice over 12 weeks treatment.
- Trial name
- NCT02811315
- Testing
- Observational. Non interventional study
- Sponsor
- Mundipharma Pharmaceuticals B.V.
HER2-Negative Advanced Breast Cancer
A Study of HB1801 Versus Docetaxel (Taxotere®) in Patients With Advanced Breast Cancer
This is a randomized, open-label, multicenter Phase Ⅲ clinical trial designed to evaluate the efficacy and safety of HB1801 versus Taxotere® in patients with HER2-negative advanced breast cancer.
- Trial name
- NCT07805135
- Testing
- HB1801, Docetaxel (Taxotere®)
- Volunteers
- 430 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Hip Fractures
Efficacy of Continuous Fascia Iliaca Block in Hip Surgery in Elderly
The goal of this clinical trial is to investigate the analgesic effect of ultrasound-guided Continuous fascia iliaca block in very elderly patients with hip fracture after hip surgery compared to systemic analgesia .
- Trial name
- NCT05941208
- Testing
- continuous fascia iliaca compartment block
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Ain Shams University
Heart Diseases
Evaluate Safety and Effectiveness of XenoSure Biological Patch in the Application of Cardiac Repair
The purpose of this clinical trial is to collect safety and effectiveness data to support cardiac repair indication of XenoSure biologic patch. This trial is performed to meet the China FDA regulations for this kind of device.
- Trial name
- NCT03176225
- Testing
- Open heart surgery to address the heart disease, Close the defects with XenoSure Patch, Close the defects with Chest Polyester Patch
- Where
- China
- Volunteers
- 142 people
- Sponsor
- LeMaitre Vascular
AKI - Acute Kidney Injury
Efficacy and Safety of SP16 in Preventing Acute Kidney Injury in At-risk Subjects With Chronic Kidney Disease Undergoing Elective Cardiac Surgery Using the Heart-lung-machine
This clinical study investigates the safety and potential effectiveness of the investigational drug SP16 in preventing acute kidney injury in patients with pre-existing chronic kidney disease who are undergoing cardiac surgery…
- Trial name
- EASE-AKI (NCT07661940)
- Testing
- SP16-3M
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Prenatal Anxiety, Prenatal Depression
Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy
This study aims to develop and implement a preventive intervention through a mobile application to help pregnant women feel better emotionally and cope with the changes of pregnancy in a more positive way.
- Conditions
- Prenatal Anxiety, Prenatal Depression, Wellbeing, Obstetrical Complications
- Trial name
- BienGestar (NCT06871397)
- Testing
- Biopsychosocial Cognitive Behavioral Intervention
- Where
- Spain
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Asthma
Clinical Study Evaluating Safety and Efficacy of Fluticasone Furoate and Fluticasone Propionate in People With Asthma
A randomised, double-blind, double-dummy, placebo controlled multi-centre study to evaluate the efficacy and safety of fluticasone furoate inhalation powder and fluticasone propionate inhalation powder in the treatment of asthma…
- Trial name
- NCT01436110
- Testing
- Fluticasone furoate 50mcg, Fluticasone propionate 100mcg
- Where
- 42 sites in United States, Mexico and 4 more
- Volunteers
- 351 people
- Sponsor
- GlaxoSmithKline
CDH17-positive Advanced Solid Tumors
Safety and Preliminary Efficacy of Anti-CDH17 CAR-T Cell Therapy in Patients with CDH17-positive Advanced Solid Tumors
This is a single-center, open-label, single-arm study to evaluate the safety and preliminary efficacy of anti-CDH17 CAR-T cells in patients with CDH17-positive advanced solid tumors.
- Trial name
- NCT06820424
- Testing
- Anti-CDH17 CAR-T cells infusion
- Where
- China
- Volunteers
- 30 people
- Sponsor
- 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
Dystrophic Epidermolysis Bullosa, Wound Heal
Effect of Ev.FV on Wound Healing in Dystrophic Epidermolysis Bullosa
Epidermolysis bullosa (EB) is a hereditary disease of skin tissues that causes painful bleeding blisters in the skin and mucous membrane. The prevalence of this disease is 1 in 50,000.
- Trial name
- NCT07230223
- Testing
- Ev.FV 1.0 x 1011 par/ml
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Isfahan University of Medical Sciences
Head and Neck Squamous Cell Carcinoma
The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR
This is an open-label, single-arm, phase II clinical trial to explore the efficacy and safety of de-escalation of postoperative radiotherapy in locally advanced head and neck squamous cell carcinoma with pathological complete…
- Trial name
- NCT05854823
- Testing
- dose-reduced radiotherapy
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Rheumatoid Arthritis
A Study to Assess Efficacy With Respect to Clinical Improvement in Disease Activity and Safety of Tocilizumab in Patients Wtih Active Rheumatoid Arthritis.
This single arm study will assess the effectiveness of tocilizumab in combination with traditional DMARDs with regard to the clinical improvement in disease activity (achievement of LDAS) after 24 weeks' treatment in patients…
- Trial name
- NCT00754559
- Testing
- Tocilizumab
- Where
- 81 sites in Germany
- Volunteers
- 286 people
- Sponsor
- Hoffmann-La Roche
Obese Subjects With Polycystic Ovary Syndrome (PCOS)
A Multicenter, Randomized, Double-blind, Placebo-parallel-controlled Phase II Clinical Study Evaluating the Efficacy and Safety of HRS9531 Injection in Obese Subjects With Polycystic Ovary Syndrome
Randomized, double-blind, placebo-controlled study of HRS9531 in PCOS subjects
- Trial name
- NCT06595797
- Testing
- HRS9531
- Volunteers
- 144 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Non-Small Cell Lung Cancer NSCLC
Clinical Study of Trop2 CAR-NK in the Treatment of Relapsed/Refractory Non-Small Cell Lung Cancer (NSCLC)
It is a single-center, open-labeled, single-arm, non-randomized investigator-initiated trial evaluating the efficacy and safety of anti-Trop2 U-CAR-NK Cells Therapy combined with Chemotherapy for Relapsed/Refractory Non-Small…
- Trial name
- NCT06454890
- Testing
- Anti-Trop2 CAR-NK cell
- Volunteers
- 50 people
- Sponsor
- Henan Cancer Hospital
Focal Vitiligo
Efficacy of Topical Tyrosine Versus Topical 5-Fluorouracil With Fractional Erbium YAG Laser
Vitiligo is an autoimmune disorder affecting the skin, specifically targeting pigment-producing melanocytes, leading to noticeable regions of depigmentation characterized by white spots.
- Trial name
- NCT07742982
- Testing
- Tyrosine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Aswan University
Alzheimer Disease
the Safety and the Efficacy Evaluation of Allogenic Adipose MSC-Exos in Patients With Alzheimer's Disease
Evaluate the Safety and Efficacy of Exosomes Derived from Allogenic Adipose Mesenchymal Stem Cells（MSCs-Exos）in Subjects with Alzheimer's disease.
- Trial name
- NCT04388982
- Testing
- low dosage MSCs-Exos administrated for nasal drip, mild dosage MSCs-Exos administrated for nasal drip, high dosage MSCs-Exos administrated for nasal drip
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Ruijin Hospital
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