Clinical trials: Clinical Efficacy
Irritable Bowel Syndrome, Gastrointestinal Diseases
Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome
The objective of this randomized, double-blind, placebo-controlled study is to evaluate the effectiveness of Skal Pro in alleviating symptoms, enhancing stool consistency, improving quality of life, and addressing psychological…
- Conditions
- Irritable Bowel Syndrome, Gastrointestinal Diseases, Colonic Diseases, Functional, Intestinal Disease
- Trial name
- NCT06271538
- Testing
- Skal Pro
- Where
- Malaysia
- Volunteers
- 57 people
- Sponsor
- EP Plus Group Sdn Bhd
Locally Advanced or Metastatic Solid Tumors Harboring KRAS G12C Mutation
GH21 Combined With D-1553 in KRAS G12C Mutant Advanced Solid Tumors
This s a multi-center, open-label phase Ib/II study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of GH21 combined with D-1553 in patients with advanced or metastatic solid tumors harboring KRAS G12C…
- Trial name
- NCT06435455
- Testing
- GH21, D-1553
- Volunteers
- 126 people
- Sponsor
- Suzhou Genhouse Bio Co., Ltd.
Rhinitis Allergic
Study to Assess Safety and Efficacy of Fexofenadine Hydrochloride (HCL) + Pseudoephedrine HCL Fixed Dose Combination in Indian Male and Female Participants With Allergic Rhinitis (AR) Who Are 12 Years and Above
This is a single group, Phase IV clinical trial to assess the safety and effectiveness of Allegra® D. This study will be conducted in participants with allergic rhinitis who are 12 years of age and above.
- Trial name
- FAST (NCT05720455)
- Testing
- Fexofenadine HCL and pseudoephedrine HCL
- Where
- 11 sites in India
- Volunteers
- 203 people
- Sponsor
- Sanofi
Partially Edentulous Jaw, Tooth Loss
Clinical Safety and Effectiveness of the Straumann Dynamic Navigation System Falcon
The Falcon Study is a prospective, multicenter, multinational clinical investigation evaluating the Straumann® Dynamic Navigation System (Falcon) for dental implant placement.
- Conditions
- Partially Edentulous Jaw, Tooth Loss, Dental Implant
- Trial name
- Falcon (NCT07518615)
- Testing
- Post-operative Cone Beam Computed Tomography (CBCT), Straumann Falcon Dynamic Navigation System, Dental Implants
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 75 people
- Sponsor
- Institut Straumann AG
Plaque, Dental, Gingivitis
Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.
Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided.
- Trial name
- NCT06565897
- Testing
- Test regimen, Control regimen
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection
Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017)
The study will evaluate the efficacy and safety of imipenem+cilastatin/relebactam (IMI/REL, MK-7655A) in Japanese participants with complicated intra-abdominal infection (cIAI) or complicated urinary tract infection (cUTI).
- Trial name
- NCT03293485
- Testing
- Imipenem+Cilastatin/Relebactam
- Where
- 29 sites in Japan
- Volunteers
- 83 people
- Sponsor
- Merck Sharp & Dohme LLC
Vitrectomy
Safety and Efficacy of Vitreous Delineating Agent During Vitrectomy
The purpose of this study is to evaluate the safety and efficacy of triamcinolone acetonide suspension when used for visualization of structures in the back of the eye during eye surgery.
- Trial name
- NCT00532415
- Testing
- Triamcinolone Acetonide Injectable Suspension
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Plasmodium Falciparum
NMRC-M3V-Ad-PfCA Vaccine - Clinical Trial 1
The purpose of this study is to determine whether a new investigational malaria vaccine is safe, well tolerated and effective against experimental exposure to malaria when given to healthy people with no previous exposure to…
- Trial name
- NCT00392015
- Testing
- NMRC-M3V-Ad-PfCA, NMRC-MV-Ad-PfC, NMRC-M3V-Ad-PfCA
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Chinese, Non-Small Cell Lung Cancer
Multicenter Observational Study of Chinese Non-Small Cell Lung Cancer (NSCLC) Patients With Rare Driver Gene Mutation
Title: Multicenter observational study for clinicopathological characteristics and clinical efficacy of Chinese Non-Small Cell Lung Cancer (NSCLC) patients With Rare Driver Gene Mutation.
- Trial name
- NCT04137718
- Testing
- nonIntervention
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Platinum-resistant Recurrent Ovarian Cancer
A Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer.
To evaluate the efficacy and safety of B013 in patients with platinum-resistant recurrent ovarian cancer.
- Trial name
- NCT06434610
- Testing
- B013, Paclitaxel
- Where
- 17 sites in China
- Volunteers
- 90 people
- Sponsor
- Shanghai Jiaolian Drug Research and Development Co., Ltd
Ischemic Stroke
Evaluate the Efficacy of Bu-Yang- Huan-Wu Tang（BYHWT）on Ischemic Stroke
Clinical trial; Ischemic stroke; Bu-Yang-Huan-Wu Tang （BYHWT）; Gait parameter; Quality of life Stroke is the third of ten causing death disease constantly, and it also is third of consuming healthy insurance budget.
- Trial name
- NCT02150252
- Testing
- Bu-Yang-Huan-Wu Tang
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- China Medical University Hospital
Coronary Artery Diseases
A Registry To Evaluate Safety And Effectiveness Of Everolimus Drug Eluting Stent For Coronary Revascularization
This is a prospective, multi-center registry to evaluate safety and effectiveness of the Everolimus Drug Eluting Stent for treatment coronary revascularization in Chinese patients with long lesion, small vessel or multi-vessel…
- Trial name
- SEEDS (NCT01157455)
- Testing
- Everolimus Drug Eluting Stent, Aspirin, Clopidogrel
- Where
- China
- Volunteers
- 1,900 people
- Sponsor
- CCRF Consulting Co., Ltd.
Gingival Recession
Effects of the Adjunctive Use of Hyaluronic Acid-based Gel With Coranally Advanced Flap in the Gingival Recession
The study aimed to evaluate the effect of Hyaluronic Acid-based gel use in addition to the coronally advanced flap (CAF) technique in type 1 gingival recession (RT1) on postoperative morbidity, clinical parameters, and patient…
- Trial name
- NCT07437885
- Testing
- Hyaluronic acid, Steril saline solution
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ordu University
Covid19
COVID-19: Collecting Measurements of Renin-angiotensin-system Markers, Such as Angiotensin-2 and Angiotensin 1-7
Investigators study meet the World Health Organization definition of a clinical trial because it is a prospective study in which participants will be assigned to intervention groups to investigate the effects on health outcomes.
- Trial name
- Tomeka (NCT04537585)
- Testing
- Tomeka®, "Vernonia amygdalina"
- Where
- Democratic Republic of the Congo
- Volunteers
- 2,000 people
- Sponsor
- Guyguy K Tshima, MD
Acute Apical Abscess
Antibacterial Effects of Intracanal Medicaments in Acute Apical Abscesses
This randomized clinical trial compares the antibacterial effects of calcium hydroxide and a calcium silicate-based intracanal medicament in teeth with acute apical abscesses.
- Trial name
- CAM-AAA (NCT07819240)
- Testing
- Calcium Hydroxide Intracanal Medicament, Calcium Silicate-Based Intracanal Medicament
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ataturk University
Crohn's Disease
Clinical Study of CDP870/Certolizumab Pegol in Patients With Active Crohn's Disease
This is a multi-centre, randomized, double-blind, dose response clinical study of CDP870 in patients with Crohn's disease.
- Trial name
- NCT00291668
- Testing
- Certolizumab Pegol
- Where
- 22 sites in Japan
- Volunteers
- 94 people
- Sponsor
- UCB Pharma
Infant Formula Intolerance, Well-being
Efficacy of JINLINGGUAN and TOFER Formula in Formula-fed Chinese Term Infants
Objective：The present trial aimed to assess efficacy and safety of Jin Ling Guan and Tofer infant formula on body growth, intestinal tolerance, gut microbiota and fecal residual nutrients as compared to breast-milk in term…
- Trial name
- NCT03178474
- Testing
- JINLINGGUAN Infant formula,PRO-KIDO™ I-PROTECH®, TOFER Infant formula,TOFER®, Breast milk
- Where
- 3 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Acute ST Elevation Myocardial Infarction
How Effective Are Antithrombotic Therapies in Primary Percutaneous Coronary Intervention
The purpose of this study is to compare unfractionated heparin (UFH) and bivalirudin in the performance and subsequent outcomes of Primary percutaneous coronary intervention. This will be a pragmatic trial.
- Trial name
- HEAT-PPCI (NCT01519518)
- Testing
- unfractionated heparin, Bivalirudin
- Where
- United Kingdom
- Volunteers
- 1,829 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Psoriasis
IBI112 in Moderate to Severe Plaque Psoriasis With Randomized Withdrawal and Re-treatment
The purpose of this study is to evaluate the efficacy, safety, and tolerability of IBI112 in the treatment of participants with moderate to severe psoriasis
- Trial name
- NCT06049810
- Testing
- IBI112
- Where
- China
- Volunteers
- 566 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Coronary Bifurcation Lesion
Efficacy and Safety of Sirolimus-Coated Spiral Balloon for Coronary Bifurcation Lesions
This is a multicenter, prospective randomized controlled study to evaluate the safety and effectiveness of Sirolimus-coated spiral balloon (SuperFlow®) versus Paclitaxel-coated balloon (Bingo™) in the treatment of coronary…
- Trial name
- NCT06618248
- Testing
- Sirolimus coated balloon angioplasty, Paclitaxel coated balloon angioplasty
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Dongguan TT Medical
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.