Clinical trials: Clinical Exercise
Type 2 Diabetes Mellitus
Clinical Trial to Evaluate the Safety and Efficacy of the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus Receiving Acarbose Monotherapy (MK-0431-130)
This study will evaluate whether the addition of sitagliptin reduces hemoglobin A1C (A1C) more than the addition of placebo for participants with type 2 diabetes mellitus (T2DM) on a steady dose of acarbose.
- Trial name
- NCT01177384
- Testing
- Sitagliptin phosphate, Acarbose, Glimepiride
- Volunteers
- 380 people
- Sponsor
- Merck Sharp & Dohme LLC
Rheumatoid Arthritis
Physical Activity in Patients With Rheumatoid Arthritis Treated With Adalimumab in Routine Clinical Practice
The purpose of this study was to evaluate physical activity and its changes in participants with rheumatoid arthritis (RA) who were treated with adalimumab therapy in clinical practice.
- Trial name
- PACE (NCT01756235)
- Volunteers
- 462 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Type 2 Diabetes
A Clinical Study to Evaluate the Effect of Naturlose (Tagatose)
This study is a six-month, prospective, randomized, multicenter, single- blind, controlled clinical study to evaluate the effect of three low-doses of Naturlose (Tagatose) on glycemic control and safety in subjects with Type 2…
- Trial name
- NCT00961662
- Testing
- D-Tagatose
- Where
- 13 sites in United States, India
- Volunteers
- 161 people
- Sponsor
- Robert Lodder
Cystic Fibrosis
Clinical Effects of Exercise Program Added to Pulmonary Rehabilitation in Patients With Cystic Fibrosis
The aim of this study is to investigate the effects of postural exercise program added to pulmonary rehabilitation program on quality of life, exercise tolerance and postural stability in children with Cystic Fibrosis.
- Trial name
- NCT03295201
- Testing
- Active cycle of breathing techniques (ACBT), Postural Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Marmara University
Multiple Sclerosis, Sclerosis
Aerobic Exercise for Remyelination in Multiple Sclerosis
This is a clinical trial to determine the feasibility of a stationary aerobic cycling intervention and explore if aerobic exercise independently promotes remyelination in people with multiple sclerosis (MS).
- Conditions
- Multiple Sclerosis, Sclerosis, Demyelinating Diseases, Autoimmune Diseases of the Nervous System
- Trial name
- NCT04539002
- Testing
- Aerobic exercise, Education Group Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Psychotic Disorder
Yoga and Aerobic Exercise in Psychosis
The current study aims to evaluate the impacts of yoga and aerobic exercise on neuro-cognitive function, symptoms and brain changes in early psychosis.
- Trial name
- YEP (NCT01207219)
- Testing
- Yoga therapy, Aerobic exercise
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- The University of Hong Kong
Type 2 Diabetes Mellitus
Impact of Structured Physical Activity Education Delivery in Patients With Type 2 Diabetes Mellitus
The objective of this study is to assess whether a structured exercise program compared to routine recommendation for exercise has any positive impact on disease outcome in patients with type 2 diabetes.
- Trial name
- NCT02093702
- Testing
- Physical activity and exercise education and behaviour counseling from a Registered Kinesiologist and a YMCA Wellness Coach, Unstructured Physical Activity and Exercise Education
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Royal Victoria Hospital, Canada
Immune System Diseases, Oxidative Stress
The Effect of Different Volumes of Physical Exercise on the Immune System
The investigators will do an intervention on four groups of previously sedentary post-menopausal women which consists: group 1 - 30 minutes per day of physical protocol; group 2 - 50 minutes per day of physical protocol; group 3…
- Trial name
- ProAFIM (NCT02331446)
- Testing
- Physical exercise intervention
- Volunteers
- 42 people
- Sponsor
- Federal University of Pelotas
Diabetes Mellitus, Type 2
Home-based Resistance Training to Patients With Type 2 Diabetes
The purpose of this study is to compare motivational interviews and self-efficacy theory-based exercise behavior and home-based resistance exercise (elastic band to non-elastic band) to improve physical activity, muscle strength…
- Trial name
- NCT04755660
- Testing
- Exercise behavior change for resistance exercise
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Type 2 Diabetes Mellitus
Efficacy and Safety of Ertugliflozin (MK-8835/PF-04971729) With Sitagliptin in the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Diet and Exercise (MK-8835-017)
This is a study to evaluate the efficacy and safety of ertugliflozin (MK-8835/PF-04971729) in combination with sitagliptin in the treatment of participants with Type 2 diabetes mellitus (T2DM) with inadequate glycemic control on…
- Trial name
- NCT02226003
- Testing
- Ertugliflozin, Sitagliptin, Glimepiride
- Volunteers
- 291 people
- Sponsor
- Merck Sharp & Dohme LLC
Heart Failure
Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)
Diastolic heart failure (DHF), which affects older individuals and women at a disproportionate rate, is a condition that can lead to shortness of breath and fluid build-up in the lungs.
- Trial name
- RELAX (NCT00763867)
- Testing
- Sildenafil
- Where
- 10 sites in United States, Canada
- Volunteers
- 216 people
- Sponsor
- Duke University
Endometrial Neoplasms
Diet and Physical Activity in Uterine Cancer Survivors
Endometrial cancer is the most common gynaecological cancer in developed countries with more than 75% of the patients surviving for at least five years.
- Trial name
- DEUS (NCT02433080)
- Testing
- Shape-Up following cancer treatment
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University College, London
Parkinson Disease
Effectiveness and Implementation of the HiBalance Program in Clinical Practice
This effectiveness-implementation study is a part of the larger study BETA-PD (Balance, Elderly, Training and Activity in Parkinson's Disease), which has the long-term goal to reduce the risk of falling in people with Parkinson's…
- Trial name
- BETA-PD (NCT02727478)
- Testing
- HiBalance training program
- Where
- Sweden
- Volunteers
- 117 people
- Sponsor
- Karolinska Institutet
Insulin, Exercise
Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise
To determine if physical activity engagement alters the dose-response profile and safety of administration of insulin into the intranasal mucosa.
- Trial name
- NCT04292535
- Testing
- 20 IU NovoLog Insulin aspart into the intranasal mucosa, 40 IU NovoLog Insulin aspart into the intranasal mucosa, 60 IU NovoLog Insulin aspart into the intranasal mucosa
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Patellofemoral Pain Syndrome
Therapeutic Effect of Two Muscle Strengthening Programs in Patients With Patellofemoral Pain Syndrome
Introduction: The patellofemoral pain syndrome (SPF) is one of the most frequent pathologies generated by the knee joint. Conservative treatment with physiotherapy exercises reduces pain and improves functional capacity in the…
- Trial name
- NCT04011436
- Testing
- Strengthening program
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Back Pain Lower Back
Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory)
Our clinical trial has the purpose to evaluate the effectiveness in reducing pain and improving function and quality of life during a 6-months follow-up of a therapeutic exercise program compared to pharmacological treatment with…
- Trial name
- DLSEA (NCT01374269)
- Testing
- Exercise program, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- 2 sites in Colombia
- Volunteers
- 90 people
- Sponsor
- Grupo Rehabilitacion en Salud
Parkinson Disease
Nintendo WII and Exercises at Rehabilitation of Individuals With Parkinson's Disease
Patients with Parkinson's disease present motor dysfunctions such as stiffness, tremor, postural instability and bradykinesia, which leads to alterations of balance, necessitating specialized physiotherapeutic treatment.
- Trial name
- NCT03235284
- Testing
- Exercises, Nintendo Wii, Exercises and Nintendo Wii
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Federal University of Bahia
Peripheral Arterial Disease, Intermittent Claudication
High Intensity Interval Training In pATiEnts With Intermittent Claudication
This INITIATE study evaluates the use of high-intensity interval training as a treatment modality for patients with intermittent claudication - an ambulatory leg pain caused by narrowed arteries that supply the lower limbs.
- Trial name
- INITIATE (NCT04042311)
- Testing
- High-intensity interval training
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Type 2 Diabetes Mellitus (T2DM)
Sitagliptin and Pioglitazone Mechanism of Action Study in Type 2 Diabetes Mellitus (0431-061)
A clinical study to determine the safety, efficacy and mechanism of action of sitagliptin alone and in combination with pioglitazone, in patients with type 2 diabetes mellitus who have inadequate glycemic (blood sugar) control.
- Trial name
- NCT00511108
- Testing
- Comparator: sitagliptin phosphate, Comparator: pioglitazone
- Volunteers
- 211 people
- Sponsor
- Merck Sharp & Dohme LLC
Atrial Fibrillation Paroxysmal
Efficacy of Personalized Exercise Program and Trimetazidine in Rehabilitation of Patients After RFA of AF
Atrial fibrillation (AF) is one of the most common forms of heart rhythm disorder in patients with cardiovascular diseases. The choice of treatment for AF is a complex problem, depending on the form (paroxysmal, persistent…
- Trial name
- NCT04511520
- Testing
- Physical training program, Trimetazidine
- Volunteers
- 72 people
- Sponsor
- National Research Center for Preventive Medicine