Clinical trials: Clinical Markers
Erectile Dysfunction, CTCAE
Clinical Study on the Role of Inflammatory Markers in Patients With Erectile Dysfunction
Project Title**: Clinical Study on the Role of Inflammatory Markers in Patients with Erectile Dysfunction Research Objective**: To explore the changes in the levels of inflammatory markers in patients with erectile dysfunction…
- Trial name
- NCT06798350
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Lung Cancer
Tumor Response to Pemetrexed Disodium in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Enrolled in Clinical Trial MCCRC-RC0524
RATIONALE: Studying samples of blood in the laboratory from patients receiving pemetrexed disodium may help doctors learn more about the effects of pemetrexed disodium on cells.
- Trial name
- NCT00898820
- Testing
- gene expression analysis, polymorphism analysis, protein expression analysis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Non Alcoholic Fatty Liver, Obesity
Effect of Probiotics or Berberine in Hepatic Steatosis Markers, Cardiometabolic and Microbiotic Profile in NAFL.
Effect of oral selected Probiotics (PRO) and/or Berberine (BBR) supplementation on hepatic steatosis markers, cardiometabolic profile, and gut microbiota profile in the non-alcoholic fatty liver (NAFL) - a randomized double-blind…
- Trial name
- NCT05523024
- Testing
- Probiotic, Berberine, Probiotc and Berberine
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Poznan University of Medical Sciences
Vitamin D Deficiency
Effects of Vitamin D Supplementation During Pregnancy on Clinical Outcomes and Immune Function
Researchers at the USDA Western Human Nutrition Research Center and clinicians at UC Davis Medical Center are currently conducting a study on the effects of vitamin D supplementation during pregnancy on maternal health and immune…
- Trial name
- NCT01417351
- Testing
- 400 IU vitamin D3, 2,000 IU Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Depression, Antidepressant Drug Adverse Reaction
Development of Pharmacogenomic Method to Predict Antidepressant Responsiveness
The Purpose of this study is to predict antidepressant response in advance using pharmacogenomics and peripheral biological markers in depressed patients.
- Trial name
- PG (NCT00817011)
- Testing
- SSRI treated group, non-SSRI treated group
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
P. Falciparum Malaria, P. Falciparum Malaria Mixed Infection
Evaluating the Efficacy of Artesunate-mefloquine and the Relative Roles of Resistance Genetic Markers
This is a retrospective non randomized cohort to evaluate efficacy of MAS3 on patients with uncomplicated P. falciparum malaria or mixed infection (P. falciparum + a non-falciparum species).
- Trial name
- MMA (NCT02427360)
- Where
- Thailand
- Volunteers
- 1,022 people
- Sponsor
- University of Oxford
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Gastric Cancers
Prediction of Postoperative Complications and Survival in Gastric Cancer Using Preoperative Blood Markers
Gastric cancer is one of the most common cancers worldwide, especially in East Asia. Although surgery remains the main treatment, patients may experience postoperative complications and have varying long-term survival outcomes.
- Trial name
- NCT06686966
- Testing
- gastric cancer
- Volunteers
- 3,400 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Sepsis
Clinical Protocol Validation to Identify Prognostic Markers for Critical Care Pediatric Patients
The purpose of this study is to monitor the respiratory, metabolic and nutritional status of critically ill pediatric patients undergoing mechanical ventilation and to correlate the clinical and physiopathological findings with…
- Trial name
- PCL07 (NCT00792883)
- Where
- Brazil
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Osteosarcoma in Children
Integrated Clinical-radiological Analysis of Hypoxia Markers in Pediatric Osteosarcomas
The aim of this pilot study is therefore to retrospectively measure the volume and percentage of necrosis on diagnostic MRI in T1 sequence and in parallel to study the expression of immunohistochemical markers of hypoxia (HIF-1α…
- Trial name
- SARCOMAS (NCT05107843)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Allergic Rhinitis
The Use of Hydrogen Ion Water (Shan Shang Water) in the Treatment of Allergic Rhinitis
The goal of this clinical trial is to evaluate whether Shan Shang Water (hydrogen ion water) can help treat allergic rhinitis in adults and affect immune markers.
- Trial name
- SSWAR (NCT06756243)
- Testing
- Hydrogen Ion Water（Shan Shang Water）, Budesonide Nasal Spray therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Osteoarthritis of the Knee
Efficacy of Spearmint Tea in Relieving Osteoarthritis of the Knee
The purpose of this study is to investigate the benefits of daily consumption of a high rosmarinic acid spearmint tea, developed by the University of Guelph, on measures of pain, physical function and disease activity in…
- Trial name
- NCT01380015
- Testing
- Commercially spearmint tea, High Rosmarinic Acid Spearmint Tea
- Where
- 2 sites in Canada
- Volunteers
- 49 people
- Sponsor
- University of Guelph
Ischemic Stroke, Acute, Tumor Progression
Predictive Value of Human Microbiome and Serological Markers for Clinical Outcome of AIS With Active Cancer
Explore with active cancer patients with acute ischemic stroke in the human body characteristic microorganism disorder to clinical prognosis of the predictive value of the secondary objective: to observe with active cancer…
- Trial name
- NCT05553990
- Testing
- intestinal flora disturbance
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Bone Remodeling, Vitamin D
Bone Turnover Markers and Vitamin D Survey Among Health Professionals in Taiwan
This study will provide the first national overview of BTM and vitamin D utilization among healthcare professionals in Taiwan. The findings are expected to inform educational strategies, optimize clinical implementation, and…
- Trial name
- NCT07387458
- Where
- Taiwan
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Polycystic Ovary Syndrome
OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women
Objective: To assess effectiveness of ISD (Insulin sensitizing drugs) Vs OCP (Combined E\&P cyproterone acetate) in improving clinical, hormonal and metabolic features of PCOS( polycystic ovary syndrome)women from India.
- Trial name
- OCP (NCT02744131)
- Testing
- Oral contraceptive pill combination of ethyl estradiol and Cyproterone acetate, Metformin 1500mgs per day
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Kar Clinic & Hospital Pvt. Ltd.
Inflamatory Markers
Inflammatory Markers and Clinical Score in Predicting Mortality
To evaluate the prognostic value of inflammatory markers; specifically neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic inflammation immune index (SII) in…
- Trial name
- NCT07464054
- Testing
- Blood samples for aboratory test
- Volunteers
- 61 people
- Sponsor
- Assiut University
Glioblastoma Multiforme, Glioma
Establishment of a Brain and Spinal Tumor Tissue Bank
The purpose of this study is to establish a Brain and Spinal Tumor Tissue/Specimen repository to serve as a resource for current and future scientific studies.
- Conditions
- Glioblastoma Multiforme, Glioma, Neuroectodermal Tumors
- Trial name
- NCT00686387
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Taipei Medical University WanFang Hospital
Ovarian Cancer, Borderline Ovarian Tumors
Treg, Th17 Cells, NKT in Epithelial Ovarian Tumor
The aim of the study was to estimate the percentage and of Treg, Th17 and NKT in peripheral blood and the tissue of the epithelial ovarian tumor and relationship with blood serum level of HE4, CA125, as well as algorithm ROMA.
- Conditions
- Ovarian Cancer, Borderline Ovarian Tumors, Benign Ovarian Tumor, Unexplained Infertility
- Trial name
- NCT03779399
- Testing
- Assessment of percentage of Treg, Th17, NKT and serum level of HE4, CA125 and ROMA.
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Dyslipidemia
Hs-CRP as Clinical Marker of Inflammatory Atherogenic Dyslipidemia
The objective of this proposal is to study the applicability of the hs-CRP assay in the assessment of CV risk in daily clinical conditions where hyperlipidemic population with or without CHD are currently evaluated.
- Trial name
- NCT00169871
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Non-muscle Invasive Bladder Cancer
Validation of a Urine-based Assay With Genomic Markers for Predicting Recurrence for Non-muscle Invasive Bladder Cancer
A study to validate, in a prospective manner, the ability of the predefined Genomic Health bladder cancer assay to detect recurrence in patients undergoing surveillance for non-muscle invasive bladder cancer.
- Trial name
- NCT02969109
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- Genomic Health®, Inc.