Clinical trials: Clinical Performance, active
Dental Caries, Dental Adhesive Materials
Clinical Performance of Bioactive Restorative Materials
The aim of this clinical study is to evaluate the performance of three different bioactive restorative materials against a composite resin for a period of 9 months.
- Trial name
- Bioactive (NCT07394751)
- Testing
- Tetric N Ceram Bulkfill application, Cention Forte application, Stela Automix
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Carotid Artery Stenosis
Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)(Extended Follow-Up)
Purpose: To assess the long-term safety and efficacy of the intravascular lithotripsy system for pre-treatment of calcified carotid artery stenosis.
- Trial name
- NCT06936189
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Shanghai Bluesail Boyuan Medical Technology Co., Ltd.
Primary Open Angle Glaucoma
PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group
The purpose of this study is to collect safety and performance data on the PRESERFLO™ MicroShunt XI in patients diagnosed with primary open angle glaucoma who are inadequately controlled on maximum tolerated medical therapy with…
- Trial name
- NCT07235592
- Testing
- Microshunt XI
- Where
- 12 sites in Austria, Belgium and 6 more
- Volunteers
- 112 people
- Sponsor
- Santen SAS
AI (Artificial Intelligence), Large Language Model
OpenEvidence Safety and Comparative Efficacy of Four LLM's in Clinical Practice
OpenEvidence is an online tool that aggregates and synthesizes data from peer-reviewed medical studies, then producing a response to a user's questions using generative AI.
- Conditions
- AI (Artificial Intelligence), Large Language Model, Generative Artificial Intelligence
- Trial name
- NCT07199231
- Testing
- AI clinical reference tool
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Clinical Performance of Endodontically Treated Teeth Restored With Endocrowns, Restoration Fit of Endodontically Treated Teeth With Endocrowns
Clinical Performance and Fit of 3D-Printed Versus Milled Endocrowns: An 18-Month Trial
The goal of this clinical trial is to learn whether 3D-printed resin composite endocrowns perform as well as milled resin composite endocrowns in restoring endodontically treated teeth.
- Trial name
- Endocrowns (NCT07708077)
- Testing
- Milled resin composite restorations fabricated using subtractive manufacturing from CAD/CAM blocks., Three dimensionally (3D) printed resin composite restorations fabricated using additive manufacturing
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- October 6 University
Disc Herniation, Disk Herniated Lumbar
Safety And Performance Of Disc Care To Prevent Lumbar Disc Herniation Recurrence
The goal of this clinical investigation is to learn about DISC Care, an Hernia Blocking System, in patients who have undergone lumbar disc hernia surgery.
- Trial name
- ACE-2 (NCT06023719)
- Testing
- DISC Care
- Where
- 7 sites in Spain
- Volunteers
- 30 people
- Sponsor
- NEOS Surgery
Endodontic Treatment
A Study to Assess the Clinical Success of Root Canal Treatment Using Novel Obturation Material.
The goal of this study is prospective, single-arm, non-randomized controlled trial to test the effectiveness, safety and performance of a novel dental obturation material. The main question sit answers is 1.
- Trial name
- NCT06312085
- Testing
- Endofill
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lumendo AG
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Root Resorption, Pain Perception
AI-Designed Clear Aligners: A Randomized Clinical Trial
The goal of this clinical trial is to evaluate the clinical performance and validity of applying AI-based TruRoot-designed clear aligners in adult orthodontic patients.
- Conditions
- Root Resorption, Pain Perception, Treatment Duration
- Trial name
- NCT06968325
- Testing
- AI-based TruRoot group:, Conventional clear aligner group
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Breast Augmentation, Breast Reconstruction
Evaluation of the Performance and Safety of the Monobloc® - Silicone SoftOne® Breast Implants at 10 Years
The aim of this observational, Post-market, Retro-prospective, open, non-randomized, non-comparative, multicentric, European study is to evaluate the safety and performance of the Monobloc® - Silicone SoftOne® breast implants at…
- Trial name
- SOFTONE (NCT07904091)
- Testing
- Breast augmentation, Breast reconstruction
- Where
- 5 sites in France
- Volunteers
- 630 people
- Sponsor
- Laboratoires ARION
Comparison of Bulk Fill vs HVGIC in Class II Cavities
Clinical Performance of HVGIC vs Bulk Fill Composite in Class II Cavities of Posterior Teeth: A 12-Month RCT
Study Title: Clinical Performance of Highly Viscous Glass Ionomer versus Bulk Fill Resin Composite Restorative Materials in Moderate Class II Cavities of Permanent Posterior Teeth: A 12-Month Randomized Clinical Study Study…
- Trial name
- NCT07067164
- Testing
- Bulk fill resin composite restorative material
- Where
- Egypt
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Virtual Reality
Virtual Reality-Supported Relaxation Before Objective Structured Clinical Examination
Accurate and objective assessment of clinical competencies is essential in nursing education to ensure that students acquire professional skills and contribute to the quality of patient care.
- Trial name
- NCT07864428
- Testing
- Experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Emine Arici Parlak
Hypertrophic Scars, Keloids
Scar Gel Product Family Clinical Investigation
The purpose of this PMCF investigation is to determine whether there are differences between the two formulations (Dermatix and Dermatix Ultra) in improving keloid and hypertrophic scars clinical symptoms and in the overall scar…
- Trial name
- NCT07684573
- Testing
- Dermatix, Dermatix Ultra
- Volunteers
- 150 people
- Sponsor
- Hanson Medical, Inc.
Angle Class I Malocclusion, Dental Crowding
Clinical Performance of Direct-Printed Versus Thermoformed Aligners
The goal of this study is to evaluate and compare the clinical effectiveness of in-office directly 3D-printed clear aligners versus conventional multilayered thermoformed aligners.
- Conditions
- Angle Class I Malocclusion, Dental Crowding, Tooth Spacing
- Trial name
- NCT07637227
- Testing
- Direct-Printed Aligner, Thermoformed aligner
- Where
- 3 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Athlete, Probiotic
Clinical Trial of Lactiplantibacillus Plantarum Dad-13 on Gut Microbiota Profile and Performance in Adolescent Athletes
The aim of this research is to analyze the effect of a Lactiplantibacillus plantarum Dad-13 supplementation on the gut microbiota profile and performance of adolescent athletes.
- Conditions
- Athlete, Probiotic, Performance, Gut Microbiota
- Trial name
- Dad-13 (NCT07476573)
- Testing
- Probiotic Lactiplantibacillus plantarum Dad-13
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Musculoskeletal Disorders in Violinists
Effects of Scapulothoracic Stabilization Exercises in Violinists
This study aims to investigate the effects of scapulothoracic stabilization exercises on pain, muscle strength, upper extremity function, and occupational performance in individuals who play the violin.
- Trial name
- NCT07910045
- Testing
- Postural Correction and Flexibility Exercise Program, Scapulothoracic Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Endodontically Treated Teeth
Milled vs 3D-Printed Partial-Coverage Restorations in Endodontically Treated Molars
The goal of this clinical trial is to compare the clinical performance of Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM)-milled and 3D-printed composite resin partial-coverage restorations in endodontically…
- Trial name
- NCT07643311
- Testing
- Milled Composite Resin Onlay/Overlay Restoration, 3D-Printed Composite Resin Onlay/Overlay Restoration
- Where
- Chile
- Volunteers
- 142 people
- Sponsor
- Hospital San Jose
Breast Reconstruction, Mammary Reconstruction
A Clinical Study Evaluating the Safety and Performance of Eurosilicone Integrated Valve Tissue Expanders (IVTE)
Patients can undergo breast reconstruction surgery in two stages before implantation of the permanent prosthesis for several reasons.
- Trial name
- NCT07842406
- Testing
- Breast reconstruction surgery
- Volunteers
- 100 people
- Sponsor
- GCA (Eurosilicone)
Heart Failure, Functional Capacity
Rhythmic Auditory Stimulation in Heart Failure Patients
The aim of this study was to investigate the acute effects of rhythmic auditory stimulation (RAS) with metronome on functional capacity, vital signs, perceived fatigue, and dyspnea in patients diagnosed with heart failure.
- Trial name
- NCT07864363
- Testing
- functional capacity, Fatigue and dyspnea
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Necmettin Erbakan University
Psychological Stress, Anxiety
NeuroFinance Human Stress Trial During Financial and Informational Volatility
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven…
- Conditions
- Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction
- Trial name
- NFHST (NCT07622589)
- Testing
- Wearable Physiologic Monitoring Platform
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.