Clinical trials: Clinical Pregnancy Rate
Chronic Kidney Disease, Iron-deficiency Anemia
A Clinical Trial of Oral Versus IV Iron in Patients With Chronic Kidney Disease
The long-term goal is to assess the fall in kidney function measured by glomerular filtration rate (GFR) when patients with chronic kidney disease (CKD) are exposed to intravenous iron (IVIR).
- Trial name
- NCT00830037
- Testing
- IV Iron, Ferrous Sulfate
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Indiana University
Infertility, Reproductive Issues
Impact of a Predetermined Day 5 ET vs. a Predetermined Day 6 ET on Clinical Pregnancy Rate After ICSI Treatment
The aim of this prospective multicenter study is to investigate the influence of a predetermined embryo transfer on day 6 compared to a predetermined embryo transfer on day 5.
- Trial name
- NCT06447077
- Where
- Germany
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Infertility
Low-dose GH Supplementation Increases Clinical Pregnancy Rate
The objective of this study is to assess whether a low dose of GH supplementation (0.5 IU/day) increases clinical pregnancy rates in women with a history of POR who failed to become pregnant in two previous IVF cycles.
- Trial name
- NCT02359695
- Testing
- Growth Hormone
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Centro de Infertilidad y Reproducción Humana
Labor Pain, Analgesia, Epidural
A Study on the Effect of Position on Walking Labour Epidural Efficacy
This study is being done to better understand how patient positioning can affect pain relief after an epidural. In addition to pain, the investigators will assess how position affects epidural spread, and its effects on maternal…
- Trial name
- NCT04469101
- Testing
- Lumbar Epidural
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Polycystic Ovary Syndrome, Infertility, Female
Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females
This research study aims to investigate the effect of adding Alpha lipoic acid (ALA) supplement to letrozole treatment in infertile women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06418347
- Testing
- Alpha lipoic acid, Letrozole
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome, Infertility
Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate
Women with polycystic ovary syndrome (PCOS) can suffer from infertility because they do not produce an egg each month, resulting in irregular periods.
- Trial name
- NCT01966575
- Testing
- Progestin
- Where
- Canada
- Sponsor
- University of British Columbia
Infertility
Observation of the Response to Ovulation Triggering on the Day of Intrauterine Insemination and Correlation Between Progesterone Level and Pregnancy Rate (OVUL-IIU)
Intrauterine inseminations (IUI) are a commonly used technique in assisted reproductive technology (ART) to help women conceive, whether within a couple or as single individuals.
- Trial name
- OVUL-IIU (NCT07038616)
- Where
- France
- Volunteers
- 158 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Sterility, Female
Endometrial Local Injury Before First IVF : Evaluation of Pregnancy Rate
In spite of all progress realized in the field of assisted reproduction the pregnancy rate by In vitro fertilization (IVF) in France, across indications, is only 23% after IVF cycle.
- Trial name
- BEONE (NCT02522806)
- Testing
- endometrial biopsy
- Where
- France
- Volunteers
- 315 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Clinical Pregnancy, Live Birth
Efficacy Study of Segmentation of PGD Treatment
A single centre observational study into the segmentation of preimplantation genetic diagnosis (PGD) treatment by comparing cumulative pregnancy rates following cryopreservation of all genetically transferable embryos after PGD…
- Trial name
- NCT02133950
- Testing
- elective cryopreservation of available embryos after PGD, PGD and elective fresh embryo transfer plus cryopreservation of supernumerary available embryos after PGD
- Where
- Belgium
- Volunteers
- 252 people
- Sponsor
- Universitair Ziekenhuis Brussel
Recurrent Implantation Failure, Endometriosis
Effect of Granulocyte Colony-stimulating Factor on Clinical Pregnancy Rate in Patients With Endometriosis
The aim of this study is to evaluate the effect of granulocyte colony-stimulating factor on clinical pregnancy rate in patients with endometriosis undergoing in-vitro fertilization after recurrent implantation failure.
- Trial name
- NCT03549728
- Testing
- Granulocyte Colony-Stimulating Factor, Intrauterine infusion of normal saline
- Volunteers
- 88 people
- Sponsor
- Amira Magdi Guergues Selim
Hypotension, Cesarean Section
Different Noradrenaline Protocols in Post Spinal Hypotension in CS
The incidence of hypotension after spinal anesthesia is approximately 60% in parturients undergoing cesarean section. As a consequence of hypotension, nausea-vomiting, dyspnea and neurological deterioration in patients and low…
- Conditions
- Hypotension, Cesarean Section, Anesthesia, Spinal
- Trial name
- NCT04701190
- Testing
- Noradrenalin 10 microgram bolus, Noradrenaline 5 microgram bolus, Noradrenaline 0.1 microgram/kg/minute infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Ankara University
Clinical Pregnancy Rate
Does the Volume of the Embryo Culture Medium During Embryo Transfer Affects the IVF Outcomes?
The aim of this study was to evaluate if higher volume (40-45μl VS 20-25 μl) of media used for embryo transfer affects the clinical outcomes in fresh IVF cycles.Patients who fulfilled the inclusion criteria and agreed to…
- Trial name
- NCT03350646
- Testing
- Volume of medium during embryo transfer
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Aretaieion University Hospital
Polycystic Ovary Syndrome
The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome
We hypothesise that fish oils will have a beneficial effect on cardiometabolic parameters in women with PCOS. The purpose of this study therefore is to examine the effects of fish oils on blood pressure, heart rate variability…
- Trial name
- fops (NCT00620529)
- Testing
- Ocean Nutrition 2050, Olive oil capsules
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Keogh Institute for Medical Research
Embryo Development
Outcome of Embryo Culture at Two Oxygen Tensions
The purpose of this study is to assess whether reduced oxygen tension in embryo culture has any effect on clinical outcome.
- Trial name
- NCT00718822
- Testing
- oxygen concentration in the culture atmosphere
- Where
- Slovenia
- Volunteers
- 647 people
- Sponsor
- University Medical Centre Maribor
Clinical Pregnancy After Single Embryo Transfer
Embryo Selection by Time Lapse Monitoring for Single Embryo Transfer ("SET")
A multiple pregnancy is an undesired outcome of assisted reproduction. Current embryo selection technologies are inefficient in identifying the embryo with the highest implantation potential.
- Trial name
- NCT01694641
- Testing
- time-lapse morphokinetic evaluation
- Where
- 2 sites in Hungary
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Dunamenti REK Istenhegyi IVF Center
Advanced Age, Recurrent Pregnancy Loss(RPL)
Noninvasive Implantation Potential vs Morphology-Based Selection in IVF Single Blastocyst Transfer
Background: Morphology-based embryo selection cannot detect aneuploidy, which is common in advanced maternal age and recurrent pregnancy loss.
- Conditions
- Advanced Age, Recurrent Pregnancy Loss(RPL), Infertility (IVF Patients), Sequence Analysis
- Trial name
- NICSAI-SBT-RCT (NCT07461077)
- Testing
- NICS-AI, Morphology group
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
PGT-A, PCOS
PIMS vs PGT-A in Infertile PCOS Patients
This experiment has become a serious issue for two reasons: DNA methylation plays an important role during embryogenesis, global abnormal methylome reprogramming often occurs in human embryos, and DNA methylome pattern is…
- Conditions
- PGT-A, PCOS, PIMS
- Trial name
- NCT06887881
- Testing
- PIMS screening, PGT-A screening
- Where
- China
- Volunteers
- 766 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Pregnancy
Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles
Position of the tip of the inner catheter and air bubbles detection (at time,5min 10min)during embryo transfer influence the pregnancy rate in ICSI cycles .
- Trial name
- NCT02942472
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Female Infertility, Embryo Development
Day-4 Embryo Defragmentation: Blastocyst Rate and clInical Outcomes
Background: Embryo fragmentation is one of the main morphological parameters assessed during in vitro culture in assisted reproductive technology (ART).
- Conditions
- Female Infertility, Embryo Development, In Vitro Fertilization
- Trial name
- DEBRIS (NCT07500337)
- Testing
- Mechanical embryo defragmentation at Day 4 (morula stage), Standard embryo culture without intervention
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- Momo Fertilife
Ongoing Pregnancy Rate
High Versus Free Humidity Incubators; A Randomized Clinical Trial
To compare Top quality embryos either day3 or day 5, Pregnancy rate and most importantly ongoing pregnancy rate between high humidity incubators and humidity free incubators
- Trial name
- NCT01695096
- Testing
- The Embryos will be cultured on a humidity free incubator, The Embryos will be cultured on a >95% humidity incubator
- Where
- 2 sites in Egypt
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital