Clinical trials: Clinical Study - RCT
Depression
Neurophysiological RCT of Qigong in Elderly With Depression
Summary of Project: Elderly depression is a common mood disorder and the individuals will have persistent low mood and self-absorption that adversely affect their quality of life.
- Trial name
- NCT05000788
- Testing
- Qigong, Exercise
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Refractory Anastomotic Esophageal Strictures
WallFlex Esophageal Fully Covered (FC) Benign Anastomotic Stricture
The purpose of this of this study is to compare the safety and effectiveness of temporary indwell of the WallFlex Esophageal FC Metal Stent to Bougie Dilation for the treatment of refractory anastomotic esophageal strictures
- Trial name
- E7025 (NCT01699542)
- Testing
- WallFlex Esophageal RX Fully Covered Stent, Esophageal Bougie Dilator Per Investigator preference
- Where
- 4 sites in Brazil, Netherlands and 1 more
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Gastric Cancer, RCT
Perioperative Ivonescimab Plus S-1 and Oxaliplatin (SOX) for Locally Advanced Gastric or GEJ Adenocarcinoma
The purpose of this clinical trial is to evaluate whether perioperative ivonescimab in combination with S-1 and oxaliplatin (SOX) is effective in treating locally advanced gastric or gastroesophageal junction (GEJ)…
- Trial name
- Huaxi (NCT07374250)
- Testing
- Ivonescimab (20mg/kg Q3W), Oxaliplatin, S-1
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Sichuan University
Systemic Lupus Erythematosus (SLE)
A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State
Systemic Lupus Erythematosus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems. This study will evaluate how well elsubrutinib and upadacitinib given alone or as the ABBV-599 combination…
- Trial name
- NCT04451772
- Testing
- Elsubrutinib, Upadacitinib
- Where
- 87 sites in United States, Argentina and 16 more
- Volunteers
- 185 people
- Sponsor
- AbbVie
Widespread Chronic Pain
The Maintaining Musculoskeletal Health Study
It is known from many studies that when patients have developed chronic widespread pain (CWP) or fibromyalgia that managing such symptoms is extremely challenging for both doctors and patients.
- Trial name
- MAmMOTH (NCT02668003)
- Testing
- Cognitive Behavioural Therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Uterine Myomas
Randomized Controlled Trial (RCT)Comparing GYNAECARE MORCELLEX Versus ROTOCUT GI Tissue Morcellators
To date, laparoscopic approach may apply to several gynecologic diseases. Among the recent advances in laparoscopy an important role was assumed by the methods of tissue extraction.
- Trial name
- NCT00743080
- Testing
- Laparoscopic myomectomy and supracervical hysterectomy with GYNECARE MORCELLEX, Laparoscopic myomectomy and supracervical hysterectomy with ROTOCUT G1
- Where
- Italy
- Sponsor
- University Magna Graecia
Young Adults, Sensory Processing Sensitivity
Art-based Beauty Appreciation Intervention
This study is a randomized controlled trial with an active control condition evaluating the impact of an art-based beauty appreciation (ABBA) intervention on trait appreciation of beauty as a primary outcome and well-being and…
- Trial name
- ABBA-vention (NCT06788496)
- Testing
- Art-based Beauty Appreciation Intervention Program (Learning to See Beauty), Observation Program (Learning to Observe Life)
- Where
- Netherlands
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cardiorespiratory Failure
Motivational Program on Physical Activity in Cardio-respiratory Patients: an RCT Study
According to actual scientific evidence, the interventions on the general population aiming at regular physical activity are one of the most efficient strategies for health improvement.
- Trial name
- NCT05318482
- Testing
- Motivational group, Control group
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Portal Hypertension, Bleeding Gastric Varices
TIPS in Fundal Variceal Bleeding (the TFB Study)
In the last years, important advances have been done in the treatment and prevention of fundal variceal bleeding in patients with cirrhosis.
- Trial name
- TFB (NCT02364297)
- Testing
- Early TIPS
- Where
- 5 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
High Blood Pressure
Lowering Blood Pressure by Changing Lifestyle
Introduction: High blood pressure is an independent risk factor of cardiovascular disease (CVD) and is a major cause of disability and death.
- Trial name
- LBP (NCT04505150)
- Testing
- Lifestyle changes, e.g., take part in regular exercise, quitting smoking, and reduce salt consumption
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Organisation for Rural Community Development, Bangladesh
Quality of Life
Food as Medicine: An RCT to Study the Effect of Home Delivered, Medically Tailored Meals on Patients With Metastatic Cancer
The purpose of this study is to determine whether medically tailored meals (HDTM) can improve quality of life for patients with metastatic cancer.
- Trial name
- NCT02887235
- Testing
- Home Delivered, Medically Tailored Meals (HDTM)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Alzheimer's Disease
A Prospective Multicenter RCT Study of Deep Jugular Lymphovenous Anastomosis in the Treatment of Alzheimer's Disease
This research aims to observe the efficacy and safety of surgery compared with traditional medical treatment for moderate to severe dementia in Alzheimer's disease.
- Trial name
- NCT07060391
- Testing
- Deep cervical lymphatic-venous anastomosis, Donepezil drug treatment
- Volunteers
- 186 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Degenerative Cervical Myelopathy
Rehab in Mild Stable DCM: Feasibility RCT Comparing Structured Rehabilitation to Clinical Surveillance
The goal of this feasibility RCT is to establish the feasibility of undertaking a RCT investigating the effectiveness of a multi component structured rehabilitation intervention aiming at reducing physical disability in people…
- Trial name
- RehabmildDCM (NCT06781658)
- Testing
- Structured rehabilitation intervention, Clinical Surveillance
- Where
- Ireland
- Volunteers
- 24 people
- Sponsor
- Royal College of Surgeons, Ireland
Mild Cognitive Impairment
Calligraphy Writing for Cognitive and Emotional Enhancement Among Older MCI People
This study is aimed to investigate the efficacy of an 12-week Chinese calligraphy training program for enhancing cognitive and emotional functions of older adults with mild cognitive impairment.
- Trial name
- CALLI-MCI (NCT02755792)
- Testing
- Calligraphy Training, iPad Training
- Where
- Hong Kong
- Volunteers
- 99 people
- Sponsor
- The Hong Kong Polytechnic University
Psychological Well-being
Impact of Forest Baths on Emotional Well-being in People With Sub-clinical Symptomatology of Anxiety and Depression
The investigators intend to evaluate patients aged 18 to 99 years with symptoms of anxiety and/or mild depression. A randomized controlled clinical trial will be carried out to evaluate the impact of the guided practice of forest…
- Trial name
- NAT-UAB (NCT05827692)
- Testing
- Intervention group A
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Laura Comendador-Vazquez
Sustainable Nutrition, Sustainable Healthy Diet
Behavior Development Training for Sustainable Nutrition
The European Federation of Dietetic Associations (EFAD) recommends sustainable nutrition to create healthy societies. Sustainable nutrition models include the Mediterranean diet, vegetarian and vegan diets, the double pyramid…
- Conditions
- Sustainable Nutrition, Sustainable Healthy Diet, Sustainable Food Consumption, Sustainable Lifestyles
- Trial name
- RCT (NCT07090993)
- Testing
- sustainable nutrition education
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Betul Uner
Menopause
Electro-acupuncture for Menopausal Transition Symptoms
This trial aimed at exploring the efficacy as well as safety of electro-acupuncture for MT symptoms.
- Trial name
- NCT02471755
- Testing
- Eelectro-acupuncture
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Health Promotion
Possible Effects of the Dietary Supplement Magnesium Compared to Placebo
The goal of this clinical trial was to investigate possible outcomes of the nutritional supplement magnesium compared to placebo in healthy, working adults.
- Trial name
- NCT06332248
- Testing
- Magnesium
- Volunteers
- 1,013 people, healthy volunteers welcome
- Sponsor
- Dan Hasson
Hepatocellular Carcinoma Recurrent
A Study of Laparoscopic Hepatectomy Versus RFA in the Treatment of Recurrent HCC
To observe and compare the short-term and long-term oncological outcome of laparoscopic hepatectomy and radiofrequency ablation in the treatment of recurrent hepatocellular carcinoma .
- Trial name
- NCT03313648
- Testing
- Laparoscopic Hepatectomy, Radiofrequency Ablation
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Southwest Hospital, China
Breast Neoplasms, Ovarian Neoplasms
Cognitive-Existential Group Therapy to Reduce Fear of Cancer Recurrence: A RCT Study
Studies show that cancer survivors have unmet needs, the most frequently cited being fear of recurrence (FCR). Moderate to high levels of FCR have been reported by as much as 49% of cancer patients and are more prevalent among…
- Conditions
- Breast Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Uterine Cervical Neoplasms
- Trial name
- NCT03270995
- Testing
- Cognitive Existential Therapy Group 1, Supportive Therapy Group 2
- Where
- 3 sites in Canada
- Volunteers
- 144 people
- Sponsor
- McGill University