Clinical trials: Clinicopathological
Leukemia
S9333A Study of Blood and Bone Marrow Samples From Patients With Previously Untreated Primary Acute Myeloid Leukemia
RATIONALE: Studying samples of blood and bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00899743
- Testing
- polyacrylamide gel electrophoresis, western blotting, immunologic technique
- Volunteers
- 132 people
- Sponsor
- SWOG Cancer Research Network
Gastric Cancer
The Functional and Clinicopathological Roles and Therapeutic Implication of Connective Tissue Growth Factor in Peritoneal Metastasis of Gastric Cancer
For the past 50 years, gastric cancer has been one of the ten most frequent cancers and the second leading cause of cancer-related death in the world.
- Trial name
- CTGF (NCT01627119)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer
Serum Endocan Levels in Colorectal Cancer
This case-control study aims to measure serum endocan levels in patients with colorectal cancer and healthy controls using ELISA and to compare the levels between the two groups.
- Trial name
- NCT07842692
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Myeloid Leukemia
Extramedullary Acute Myeloid Leukemia (eAML): Retrospective Single Center Cohort Study, Clinicopathological, Molecular Analysis and Survival Outcomes
Patients with extramedullary leukemia were identified over 10 years (January 2003 to September 2019). Clinicopathological,genetic-molecular features were identified and survival outcomes were studied and analyzed.
- Trial name
- NCT05057299
- Testing
- retrospective data analysis
- Where
- Jordan
- Volunteers
- 32 people
- Sponsor
- King Hussein Cancer Center
Lymphoma, Gene Abnormality
Correlation Between Driver Gene Abnormalities and Clinicopathological Characteristics and Disease Prognosis in Lymphoma
Correlation Between Driver Gene Abnormalities and Clinicopathological Characteristics and Disease Prognosis in Lymphoma
- Trial name
- NCT04263935
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Henan Cancer Hospital
Papillary Thyroid Carcinoma, Recurrence Free Survival
Clinicopathological Predictors of Recurrence in Papillary Thyroid Carcinoma
The goal of this observational study is to identify demographic and clinicopathological factors associated with disease recurrence in adults with histologically confirmed papillary thyroid carcinoma (PTC) who achieved an initial…
- Trial name
- NCT07695974
- Where
- Italy
- Volunteers
- 1,113 people
- Sponsor
- University of Roma La Sapienza
Colo-rectal Cancer, Molecular Pathway Deregulation
Clinicopathological Characteristics of Colon Cancer in Young Age
A Study on the Characteristics of Colorectal Cancer by Age and sex.
- Trial name
- NCT05365412
- Where
- South Korea
- Volunteers
- 1,400 people
- Sponsor
- Seoul National University Bundang Hospital
Early Hormone Receptor-positive Breast Cancer
Clinical High and Genomic Low Hormone Receptor-positive Early Breast Cancer Patients With or Without Adjuvant Chemotherapy
A prospective, randomized, comparative study to evaluate efficacy of anticancer chemotherapy in predicting prognosis and determining chemotherapy method in early Hormone Receptor-positive breast cancer patients with…
- Trial name
- NCT04278469
- Testing
- Chemotherapy Drugs, Cancer
- Where
- South Korea
- Volunteers
- 194 people
- Sponsor
- Gencurix, Inc.
Non-small Cell Lung Cancer (NSCLC)
A Study to Learn About the Tests Looking for a Gene Mutation in Adults With Lung Cancer in China (ELEGANT)
The main aim of this study is to examine the percentage of people with lung cancer who carry a certain gene mutation (epidermal growth factor receptor exon 20 insertions - EGFR ex20ins) and their frequency in Chinese participants…
- Trial name
- ELEGANT (NCT05737849)
- Testing
- No Intervention
- Where
- China
- Sponsor
- Takeda
PTEN Gene Deletion
Partial PTEN Deletion in Breast Cancer
Detection of chromosome 10q23 deletion including PTEN locus in breast cancer patients. Correlation between PTEN deletion and clinicopathological characteristics in breast cancer patients.
- Trial name
- NCT05111080
- Volunteers
- 40 people
- Sponsor
- Assiut University
HER2 Low Breast Cancers
Clinicopathological Parameters of HER2 Low Breast Cancers
This was a retrospective cohort study which included all histologically proven cases of breast cancer in the 2 years from January 2022- December 2023 at a tertiary care centre.
- Trial name
- NCT06433804
- Testing
- HER2 IHC
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Vardhman Mahavir Medical College And Safdarjung Hospital
HNSCC, AI
10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma
Introduction: The incidence of occult cervical lymph node metastases (OCLNM) is reported to be 20%-30% in early-stage oral cancer and oropharyngeal cancer.
- Conditions
- HNSCC, AI, Radiomic, MRI
- Trial name
- NCT06366906
- Testing
- The Resnet50 deep learning (DL) model
- Where
- 2 sites in China
- Volunteers
- 319 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pancreatic Adenocarcinoma
HER-2 Expression in Pancreatic Duct Adenocarcinoma
Pancreatic duct adenocarcinoma is a highly aggressive carcinoma that is associated with a poor prognosis. Detection of novel biological markers that are specifically over expressed in pancreatic duct adenocarcinoma and their…
- Trial name
- NCT06055647
- Testing
- immunohistochemical approach
- Volunteers
- 37 people
- Sponsor
- Sohag University
Hepatocellular Carcinoma
The Clinicopathological and Prognostic Factors of Hepatocellular Carcinoma; 10 Years' Tertiary Center Experience in Egypt
This study aimed at study the clinical and pathological criteria of Hepatocellular carcinoma to keep with new challenging in diagnosis and morpho-molecular classifications
- Trial name
- NCT05047146
- Testing
- Morphological classifications of HCC
- Where
- Egypt
- Volunteers
- 530 people
- Sponsor
- Sadat City University
Gestational Trophoblastic Neoplasias (GTN)
Clinicopathological Features , Outcomes and Prognostic Factors of High Risk Patients of Gestational Trophoblastic Neoplasia
Aim of the Study This study aims to investigate the clinical and pathological features, treatment outcomes, and prognostic factors in high-risk patients with Gestational Trophoblastic Neoplasia (GTN).
- Trial name
- NCT06900699
- Volunteers
- 42 people
- Sponsor
- Assiut University
Prostate Adenocarcinoma
ERG Protein Expression in Prostatic Adenocarcinoma and Its Clinicopathological Features
Evaluation the ERG expression in prostatic acinar adenocarcinoma and its association with clinicopathological features.
- Trial name
- NCT04825691
- Testing
- Immunohistochemistry of prostate biopsy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Periampullary Cancers With Obstructive Jaundice, Pancreas Head Cancer
Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers
Preoperative biliary drainage methods include percutaneous transhepatic biliary drainage (PTBD), endoscopic nasobiliary drainage (ENBD), and endoscopic retrograde biliary drainage (ERBD).
- Conditions
- Periampullary Cancers With Obstructive Jaundice, Pancreas Head Cancer, Bile Duct Cancer, Ampulla of Vater Cancer
- Trial name
- NCT01134276
- Testing
- biliary drainage
- Where
- South Korea
- Volunteers
- 211 people
- Sponsor
- Seoul National University Hospital
Colitis, Ulcerative
The Associations of Microribonucleic Acid Gene Polymorphisms With the Risk of Ulcerative Colitis
From January 2020 to December 2024, diagnosed ulcerative colitis(UC) patients and gender- and age-matched normal controls were enrolled from the Department of Gastroenterology, the Second Affiliated Hospital of Wenzhou Medical…
- Trial name
- NCT06873711
- Testing
- vedolizumab
- Where
- China
- Volunteers
- 926 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Esophagus Cancer, Gastric Cancer
HER2 Status in Esophagogastric Adenocarcinoma and Its Associations With Patient's Clinicopathological Outcomes
Targeted therapies offer promise to improve oncologic outcomes in esophagogastric adenocarcinoma (EGA). The landmark 'Trastuzumab for gastric cancer (ToGA)' trial established the therapeutic value of Human Epidermal Growth Factor…
- Conditions
- Esophagus Cancer, Gastric Cancer, HER2-positive Cancer, HER2-low Cancer
- Trial name
- HERA (NCT06550063)
- Where
- Ireland
- Volunteers
- 2,188 people
- Sponsor
- St. James's Hospital, Ireland
Invasive Breast Cancer
EpCAM and p53 Expressions in Infiltrating Duct Carcinoma of the Breast
Breast cancer represents the most frequently diagnosed cancer in women. It represents the 5th leading cause of cancer mortality all over the world.
- Trial name
- NCT05703815
- Volunteers
- 40 people
- Sponsor
- Sohag University