Clinical trials: Clomiphene Citrate
Infertility
Extended Letrozole Regimen Versus Clomiphene Citrate for Superovulation in Patients With Unexplained Infertility Undergoing Intrauterine Insemination
The aim of this randomized controlled trial is to compare the efficacy of extended letrozole regimen (2.5mg/day from cycle day 1 to 9) with clomiphene citrate (100 mg/day from cycle day 3 to 7) in women with unexplained…
- Trial name
- NCT01232075
- Testing
- Extended letrozole regimen, Clomiphene citrate regimen
- Where
- 2 sites in Egypt
- Volunteers
- 214 people
- Sponsor
- Cairo University
Endometriosis
Efficacy of Letrozole and CC Alone in an IUI Program in Cases With Surgically Treated Minimal to Mild Endometriosis
To evaluate pregnancy rates with letrozole and CC alone in an IUI program for women with recently surgically treated minimal to mild endometriosis.
- Trial name
- NCT01334762
- Testing
- Letrozole/IUI, CC/IUI
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Mansoura University
Infertility
Comparison of Clomiphene Citrate and Gonadotropins in Ovulation Induction Cycles
The purpose of the present study is to analyse prospectively if highly purified hMG compared with increased dose of clomiphene citrate has different outcomes in folliculogenesis in ovulation induction cycles.
- Trial name
- cc versus FSH (NCT00835744)
- Testing
- clomiphene citrate, gonadotropins
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Polycystic Ovarian Syndrome
Letrozole Versus Clomifene Citrate for Ovulation Induction
The primary aim of the study is to assess the efficacy of letrozole as an ovulation induction agent and to test the hypothesis that letrozole will generate better pregnancy rates with fewer multiple pregnancies and higher live…
- Trial name
- NCT00478504
- Testing
- Letrozole, Clomifene citrate
- Where
- United Kingdom
- Volunteers
- 159 people
- Sponsor
- University of Nottingham
Hypogonadotropic Hypogonadism, Type 2 Diabetes
Hypogonadism in Young Men With Type 2 Diabetes
Low testosterone production, known clinically as hypogonadism, appears to be common complication of type 2 diabetes, affecting one in three diabetic men.
- Trial name
- NCT01155518
- Testing
- testosterone, clomiphene
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- State University of New York at Buffalo
Polycystic Ovarian Syndrome
The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)
As both medications i.e. CC and letrozole have been shown to be effective in inducing ovulation in PCOS patients, this study was performed in order to evaluate which regime (whether CC or letrozole) is the best to be used as the…
- Trial name
- NCT01577017
- Testing
- Letrozole
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nik Hazlina
Ovarian Response
The Effect of Oxytocin (OT) and Oxytocin Plus Human Chorionic Gonadotropin (hCG), in Cycles Induced by Letrozole or Clomiphene Citrate
The specific aims of this study were to assess whether letrozole as an aromatase inhibitor plus hCG or OT alone, or in combination compared with CC, improves ovarian response.Ethical design of this study is based on the ethical…
- Trial name
- NCT00844350
- Testing
- letrozole , oxytocin,hCG,clomiphene citrate
- Volunteers
- 177 people
- Sponsor
- Tabriz University
Polycystic Ovary Syndrome, Insulin Resistance
Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin
The results of studies conducted until now does not determine what the best way to treat infertility in the first line with patients with Polycystic ovary syndrome (PCOS).
- Trial name
- NCT01638988
- Testing
- Metformin, Clomiphene citrate
- Where
- Canada
- Sponsor
- Clinique Ovo
Unexplained Infertility
Cost-effective Treatment of Unexplained Infertility
The issue of unexplained infertility that Southam brought up in 1960 is still a problem today. Despite improvements in infertility assessment, many couples still don't know why they are infertile.
- Trial name
- NCT06178523
- Testing
- Clomiphene Citrate., Sildenafil Citrate, Intrauterine Insemination
- Where
- Saudi Arabia
- Volunteers
- 900 people
- Sponsor
- Batterjee Medical College
Infertility, Polycystic Ovary Syndrome
Treatment of Anovulatory Infertility in PCOS Patients
Clomiphene citrate (CC) and metformin are two effective drugs used to induce ovulation in patients with polycystic ovary syndrome (PCOS), even if it is still unclear which compound between them should be initially administered.
- Conditions
- Infertility, Polycystic Ovary Syndrome, Anovulation
- Trial name
- NCT00471523
- Testing
- Clomiphene citrate, Metformin
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University Magna Graecia
Secondary Hypogonadism
An Extension Study of Enclomiphene Citrate in the Treatment of Men With Secondary Hypogonadism
To determine the safety profile of Androxal in men with secondary hypogonadism.
- Trial name
- NCT01739582
- Testing
- Androxal
- Volunteers
- 300 people
- Sponsor
- Repros Therapeutics Inc.
Effect of Treatment on Bone Mineral Density
Assessment of the Effects of Enclomiphene Citrate on Bone Mineral Density in Men With Secondary Hypogonadism
To determine the effects of 12 months of treatment with Androxal on bone mineral density in men with secondary hypogonadism.
- Trial name
- NCT01619683
- Testing
- enclomiphene citrate
- Where
- 17 sites in United States
- Volunteers
- 300 people
- Sponsor
- Repros Therapeutics Inc.
Polycystic Ovary Syndrome
Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to compare and determine the efficacy of combined metformin and Clomiphene citrate administration to that of laparoscopic ovarian diathermy (LOD) in infertile women with Polycystic ovary syndrome…
- Trial name
- NCT00969631
- Testing
- metformin HCl (Cidophage®; CID,Cairo, Egypt), CC (Clomid®; Global Napi Pharmaceuticals,Cairo, Egypt),Cairo, Egypt), Laparoscopic ovarian diathermy (LOD)
- Where
- Egypt
- Volunteers
- 282 people
- Sponsor
- Mansoura University
Infertility
Thermosensitive Gels for the Vaginal Delivery of Sildenafil Citrate
The aim of this study was to develop and characterize in situ thermosensitive gels for the vaginal administration of sildenafil as a potential treatment of the endometrial thinning that occurs as a result of the use of clomiphene…
- Trial name
- ss (NCT02766725)
- Testing
- preparation F12 sildenafil in situ gel, preparation F2 sildenafil in situ gel
- Volunteers
- 90 people
- Sponsor
- Assiut University
Infertility
Comparison Between Letrozole and Laparoscopic Ovarian Drilling in Women With Clomiphene Resistant Polycystic Ovarian Syndrome (PCOS)
140 women with clomiphene resistant PCOS will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Letrozole, group 2 will have laparoscopic ovarian drilling (LOD).
- Trial name
- NCT02305693
- Testing
- Letrozole, Laparoscopic ovarian drilling
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Poor Responders Undergoing IVF
The Comparison of Effect of Four Different Treatment Protocols on IVF Outcomes in Poor Responders Undergoing in Vitro Fertilization.
The comparison of effect of four different treatment protocols: Antagonist/letrozole protocol, microdose flare-up protocol, Antagonist/clomiphene protocol, Antagonist on IVF outcomes in poor responders undergoing in vitro…
- Trial name
- NCT01948804
- Testing
- GnrH Antagonist/letrozole protocol (Cetrotide; serono + Femara; Novartis Pharma AG), microdose flare-up protocol (Lucrin; Abbott + Gonal F, Serono), Antagonist/clomiphene protocol (Cetrotide; serono + Klomen, Kocak pharma)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pınar Özcan Cenksoy
Ovulation Disorder
Human Chorionic Gonadotrophin & Trigger
In women being treated with medicines to help eggs to grow (called ovulation induction), The investigators wish to know whether adding medicines (called ovulation triggers) that help to release the egg (ovulation) would lead to…
- Trial name
- NCT02264847
- Testing
- Human chorionic gonadotrophin, clomiphene citrate alone
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypogonadotropic Hypogonadism, Prolactinoma
Clomiphene in Males With Prolactinomas and Persistent Hypogonadism
Prolactinomas are usually associated with hypogonadotropic hypogonadism in both sexes. Clomiphene citrate is a well known selective estrogen receptor modulator that increases gonadotropin secretion via hypothalamic-pituitary…
- Trial name
- NCT00697814
- Testing
- Clomiphene citrate
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Federal University of São Paulo
Infertility
Comparison Between Laparoscopic Ovarian Diathermy and Urinary Purified FSH in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome.
210 women with clomiphene resistant PCOS will be randomly divided into 3 equal groups using computer generated random numbers. Group 1 will receive combined metformin and FSH, group 2 will have LOD and group 3 will act as the…
- Trial name
- FSH (NCT02304536)
- Testing
- FSH, Laparoscopic ovarian drilling
- Where
- 2 sites in Egypt
- Volunteers
- 210 people
- Sponsor
- Cairo University
Polycystic Ovary
Clomiphene Citrate Stair-Step Protocol
A RCT will be conducted to compare the traditional clomiphene citrate regimens for ovulation induction with the stair-step protocol.
- Trial name
- NCT03178500
- Testing
- Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital