Clinical trials: Closed Head Trauma
TBI (Traumatic Brain Injury), Brain Edema
Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI
The purpose of this study is to learn if using the World Wide Web to train teens and their families in problem-solving, communication skills, and stress management strategies can help them to cope better following traumatic brain…
- Conditions
- TBI (Traumatic Brain Injury), Brain Edema, Craniocerebral Trauma, Hematoma
- Trial name
- TOPS (NCT00409058)
- Testing
- Teen Online Problem Solving
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Injury, Concussion, Intermediate
Intervention to Change Affect Recognition and Empathy
Determine the feasibility, practicality, and early efficacy of a TeleRehab program (ICARE) to improve outcomes for persons with traumatic brain injury (TBI) in recognizing and responding to others' emotions alongside their care…
- Conditions
- Traumatic Brain Injury, Concussion, Intermediate, Concussion, Severe, Concussion With LOC 31 to 59 Minutes
- Trial name
- ICARE (NCT05636020)
- Testing
- ICARE Treatment
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Indiana University
Mild Traumatic Brain Injury, Gait
Objective Dual-task Turning Measures for Return-to-duty Assessments
The overall objective is to evaluate objective dual-task turning measures for use as rehabilitative outcomes and as tools for return-to-duty assessments in individuals with mild traumatic brain injury (mTBI).This project consists…
- Conditions
- Mild Traumatic Brain Injury, Gait, Balance, Veterans
- Trial name
- reTURN (NCT03892291)
- Where
- 6 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Mild Traumatic Brain Injury, Cognitive Impairment
The Effect of Cognitive Rehabilitation Therapy in Improving Cognitive Function of Attention Following Mild Traumatic Brain Injury
This research is a randomised controlled study. The study hypothesis is cognitive rehabilitation for attention deficits following mild traumatic brain injury will improve patient's cognitive outcome, measured by…
- Trial name
- NCT03237676
- Testing
- Structured cognitive rehabilitation therapy, Patient-centred cognitive therapy
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- University of Malaya
Head Trauma, Cognitive Change
Reducing Head Impact Exposure in Hawaii High School Football
This three-year study will determine the effectiveness of a helmetless tackling training intervention to decrease head impact exposure in Hawaiian high school football players.
- Conditions
- Head Trauma, Cognitive Change, Confidence, Self, Sports Injuries in Children
- Trial name
- HuTT808 (NCT04020874)
- Testing
- HuTT-2x, HuTT-4x
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Concussion, Mild, Post Concussion Symptoms
RTL Concussion Communication
This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL).
- Conditions
- Concussion, Mild, Post Concussion Symptoms, Cognitive Impairments, Cognitive Impairments, Mild
- Trial name
- NCT06212726
- Testing
- InjureFree
- Sponsor
- University of Florida
Mild Traumatic Brain Injury
Functional MRI Study of Attention in Normal Controls and Traumatic Brain Injured Patients
The purpose of this study will be to assess the attentional ability of patients with mild to moderate traumatic brain injury (TBI) using the functional Magnetic Resonance Imaging (fMRI) technique.
- Trial name
- NCT00580918
- Testing
- functional magnetic resonance imaging fMRI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Brain Concussion
Mild Traumatic Brain Injury Discrimination
Evaluation of the utility of a multi-modal assessment tool in distinguishing between individuals with and without a history of mild traumatic brain injury.
- Trial name
- MTBID (NCT02453958)
- Testing
- Multi-modal assessment system
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Empirical Technologies Corporation
Concussion, Mild
Reverse King-Devick Test and History of Multiple Concussions
The purpose of this study is to examine the effects of concussion history and reading direction on baseline King- Devick Test (KDT) performance, a common component of sideline concussion assessments.
- Trial name
- NCT04560400
- Testing
- Conventional King-Devick test, Reverse King-Devick test
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Indiana University
Concussion, Brain
Developing a Tool to Support Shared Decision Making Post-Concussion Between Adolescents, Parents and Clinicians
Investigators will conduct a pilot efficacy test of a decision aid about contact sport participation post-concussion.
- Trial name
- NCT04777864
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Traumatic Brain Injury
Internet-Based Treatment for Children With Traumatic Brain Injuries & Their Families: Counselor Assisted Problem Solving
This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among children who have had a traumatic brain…
- Trial name
- CAPS (NCT00409448)
- Testing
- Counselor-assisted problem solving (CAPS), Internet-resource comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 132 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Concussion, Mild Traumatic Brain Injury
Interhemispheric Anterior Delta Desynchronization in Children Who Present to the Emergency Department With Acute Concussion: A Proof of Concept Study
Approximately 150,000 children present each year to emergency departments (EDs) in the US with concussion and many more are treated by primary care physician, or outpatient specialists.
- Trial name
- NCT02916108
- Testing
- Reading EEG
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Insomnia, Traumatic Brain Injury
Cognitive-Behavioral Therapy for Veterans With TBI
Many Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn era Veterans have suffered a mild traumatic brain injury (mTBI), and now cope with multiple post-injury symptoms, including sleep disturbances (especially…
- Trial name
- NCT02658669
- Testing
- Cognitive-Behavioral Therapy for Insomnia, Sleep Education
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- VA Office of Research and Development
Head Injuries, Penetrating, Head Injuries, Closed
Concordance Between Ultra-low Dose (ULD) and Standard Dose CT Scans in the Search for Traumatic Brain Injury
The aim of this research is to evaluate the diagnostic concordance of ultra low-dose and standard dose reconstructed computed tomography acquisitions using the ADMIRE algorithm to search for intracranial lesions - both…
- Trial name
- ULD-CRANE (NCT04939688)
- Testing
- Conventional dose AND ultra low-dose CT scanning in the search for cranial lesions
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Concussion, Mild Traumatic Brain Injury
Implementation of an Evidence-Based Educational Resource for Children With Mild Traumatic Brain Injury
The goal of this prospective, observational study is to (1) collaborate with our stakeholders to identify essential mTBI-information from existing evidence-based materials to develop a Post-mTBI Educational Resource for children…
- Trial name
- POCKIT (NCT07414303)
- Testing
- Post-mTBI Educational Resource
- Where
- 3 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Brain Injuries, Concussion, Mild
Evaluation and Validation of a Multimodal Brain Function Biomarker With NPC
This study is designed to collect data which will be used to associate changes in EEG, neurocognitive performance, eNPC and clinical symptoms in concussion subtypes.
- Conditions
- Brain Injuries, Concussion, Mild, Concussion, Brain, Near Point Convergence
- Trial name
- BSC-CI-NPC (NCT04074486)
- Testing
- BrainScope Ahead 300iP-O, SCAT5, Near Point Convergence
- Where
- 6 sites in United States
- Volunteers
- 1,318 people, healthy volunteers welcome
- Sponsor
- BrainScope Company, Inc.
Concussion
Effects of Vestibular Rehabilitation in the Treatment of Dizziness and Balance Disturbances After Concussion
The goal of this clinical trial is to study the effects of including vestibular rehabilitation in the treatment of dizziness and balance disturbances in athletes after concussion.
- Trial name
- NCT06700252
- Testing
- Vestibular Rehabilitation, Traditional Protocol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Beth Marschner
Concussion, Mild
Post-concussion and Transcranial Direct Current Stimulation
Children and youth are at a greater risk of concussions than adults, and once injured, take longer to recover. The increased incidence of sports-related concussion in youth and the potentially serious long-term negative impact on…
- Trial name
- NCT03481153
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of British Columbia
Traumatic Brain Injury
Internet-based Interacting Together Everyday, Recovery After Childhood TBI (I-InTERACT)--RRTC
The purpose of this study is to test two on-line interventions for families of young children who have experienced moderate or severe traumatic brain injury (TBI).
- Trial name
- I-InTERACT (NCT01214694)
- Testing
- Internet-based Interacting Together Everyday: Recovery After Childhood TBI (I-InTERACT), Internet-based-Interacting Together Everyday, Recovery after Childhood TBI Express (I-InTERACT Express), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Concussion, Mild Traumatic Brain Injury
Clinical Trial of a Rehabilitation Game - SuperBetter
Today's hospitals need innovative solutions to help patients transition from our care to self-management at home. The vast majority of the patients seen in Dodd Rehabilitation Hospital and associated clinics leave our care with…
- Conditions
- Concussion, Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury
- Trial name
- SuperBetter (NCT01398566)
- Testing
- SuperBetter play
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University