Clinical trials: Closed-loop Brain Stimulation
Aging, Noninvasive Brain Stimulation
Memory Enhancement in Aging With Closed-Loop tACS
This project optimizes high-resolution tACS to improve memory in healthy older adults, advancing drug-free approaches for ADRD. We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen…
- Conditions
- Aging, Noninvasive Brain Stimulation, Memory
- Trial name
- NCT07722598
- Testing
- Peak Frequency, Phase Lag, Peak Frequency + Phase Lag
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Visuomotor Skills, Brain Lesion (General)
Closed-loop rTMS-EEG During Visuomotor Integration.
This pilot study aims at establishing personalized state-based rTMS for precision neurorehabilitation, we designed a within-subject cross-over study to test closed-loop repetitive transcranial magnetic stimulation and…
- Trial name
- SYNC (NCT07249801)
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
PARKINSON DISEASE (Disorder)
Optimizing Adaptive DBS for Parkinson's Disease
Parkinson's disease (PD) affects more than 10 million people worldwide and causes progressive motor symptoms such as slowness, stiffness and tremor.
- Trial name
- OPT-aDBS (NCT07798271)
- Testing
- aDBS-Extended (Medtronic Percept™), aDBS-Standard (Medtronic Percept™), Continuous DBS (cDBS) - Active Control (Medtronic Percept™)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, Davis
Essential Tremor, Parkinson's Disease (PD)
Closed-loop TMS for Tremor
This study investigates the potential of phase-locked transcranial magnetic stimulation (TMS) as a non-invasive intervention for tremor in patients with Essential Tremor (ET) and Parkinson's Disease (PD).
- Trial name
- NCT07574164
- Testing
- TMS
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Major Depressive Disorder
Brain Oscillation-synchronized Stimulation of the Frontal Cortex in Major Depressive Disorder
Major depressive disorder (MDD) is a common severe psychiatric disease with enormous socioeconomic costs for the patient and society alike.
- Trial name
- BOSSFRONT2 (NCT06345651)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Tuebingen
Quadriplegia
Sensory Motor Transformations in Human Cortex
This research study is being conducted to develop a brain controlled medical device, called a brain-machine interface. The device will provide people with a spinal cord injury some ability to control an external device such as a…
- Trial name
- NCT01964261
- Testing
- Neural Prosthetic System 2 (NPS2)
- Where
- 4 sites in United States
- Volunteers
- 5 people
- Sponsor
- Richard A. Andersen, PhD