Clinical trials: Cluster Headache
Cluster Headache
Cluster Headache Treatment Survey
The objective of this study is to survey patients with cluster headache about treatment effectiveness and their views on treatments. Participants will complete one brief questionnaire online.
- Trial name
- NCT06011811
- Where
- United States
- Volunteers
- 2,487 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cluster Headache
Cluster Headache Treatment With Rimegepant
The purpose of this research is to explore the efficacy of rimegepant as a preventative therapy for cluster headache.
- Trial name
- NCT05264714
- Testing
- Rimegepant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Cluster Headache
Atrioventricular Block and Cluster Headache (SEVA)
Verapamil is a calcium channel blocker widely used to treat cardiovascular diseases however it is also the first line treatment in the prevention of cluster headaches.
- Trial name
- SEVA (NCT04406259)
- Testing
- Verapamil
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cluster Headache
Repeated GON Injections in CCH
Background: The effect of repeated GON-injections has never been studied in a double-blind randomized trial as a prophylactic therapy in a well-documented group of chronic patients.
- Trial name
- REGON (NCT05324748)
- Testing
- Methylprednisolone, Saline solution
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Primary Headache, Migraine in Adolescence
nVNS for the Prevention and Treatment of Primary Headache
This study is a single-center, single-arm study. All subjects will receive the same treatment. Children and adolescents (7-20 years old) with migraine who met the inclusion criteria will be enrolled as subjects in the…
- Conditions
- Primary Headache, Migraine in Adolescence, Migraine in Children, Cluster Headache
- Trial name
- NCT06277063
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Headache Disorders, Primary, Headache Disorders, Secondary
China Headache and Vertigo Registry Study
In the Chinese Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular…
- Conditions
- Headache Disorders, Primary, Headache Disorders, Secondary, Migraine, Tension-Type Headache
- Trial name
- CHRS (NCT04939922)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Cluster Headache
LSD to Improve Cluster Headache Impact Trial
This study aims to investigate the efficacy and safety of LSD 25μg every 3 days for 3 weeks versus placebo in the treatment of chronic cluster headache (cCH).
- Trial name
- LICIT (NCT05477459)
- Testing
- LSD tartrate
- Where
- 2 sites in Netherlands
- Volunteers
- 65 people
- Sponsor
- Radboud University Medical Center
Refractory Chronic Cluster Headache
Refractory Chronic Cluster Headache: Exploring the Potential of Repetitive Transcranial Magnetic Stimulation
The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC.
- Trial name
- NCT06917144
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Hospital Universitario La Paz
Cluster Headache, Pain Management
Pulsed Radiofrequency Combined With Platelet-Rich Plasma Applied to the Sphenopalatine Ganglion in Treating Episodic Cluster Headache
Cluster headache (CH) is one of the most severe pain accompanied by ipsilateral autonomic symptoms such as lacrimation and conjunctival injection.
- Conditions
- Cluster Headache, Pain Management, Episodic Cluster Headache
- Trial name
- NCT06882278
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Beijing Tiantan Hospital
Cluster Headache
Efficacy of Light Therapy in Treatment of Chronic Cluster Headache
Cluster headache is a primary headache. The chronic form of the disease is often difficult to treat. It is now considered a chronobiological disease.
- Trial name
- LUMIAVFc (NCT06540651)
- Testing
- use of Luminettes ® with active light emission, use of Luminettes ® with a light emission presumed to have no therapeutic effect
- Where
- 2 sites in France
- Volunteers
- 48 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cluster Headache
A Research Study to Examine Cutaneous Allodynia and Cluster Headache
This is a research study examining cutaneous allodynia and cluster headaches. Cutaneous allodynia means the feeling of pain or unpleasant sensation when normally non-painful stimuli (e.g. light touch) are applied to the skin.
- Trial name
- NCT00329836
- Testing
- There are no interventions in the observational study. The symptom of allodynia was measured.
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Thomas Jefferson University
Primary Headaches (Includes Migraines, Tension, Cluster Headaches), Hydration
Hydration in Children and Adolescents With Primary Headaches
The aim of this study is to investigate the role of hydration and fluid intake in children and adolescents with primary headaches.
- Conditions
- Primary Headaches (Includes Migraines, Tension, Cluster Headaches), Hydration, Adolescent, Children
- Trial name
- H20KIDS (NCT06816849)
- Testing
- Recommended water intake
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Cluster Headache
Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache
Background: After no official research in humans in the last 40 years, research and therapeutic uses of the serotonergic psychedelic lysergic acid diethylamide (LSD) are now re-recognized and include its use in brain research…
- Trial name
- LCH (NCT03781128)
- Testing
- Lysergic Acid Diethylamide
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Cluster Headache
High Dose Vitamin D Plus Multivitamin in the Prevention of Cluster Headache
This study intends to investigate the use of high-dose Vitamin D3 plus a multivitamin in the prevention of cluster headache attacks.
- Trial name
- NCT04570475
- Testing
- Vitamin D, multivitamin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- The University of Texas Health Science Center, Houston
Headache, Cluster
SPG Pulsed Radiofrequency for Chronic Cluster Headache
Cluster headache (CH) is a devastating disorder characterized by ipsilateral headache and associated trigeminal autonomic symptoms, with a yearly prevalence of 0.1%.
- Trial name
- NCT06787677
- Testing
- PRF, NB
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Cluster Headache, Primary Headache Disorder
Treatment of Chronic Cluster Headache with TENS and ONS
The study is an investigator-initiated, prospective, randomized, placebo-controlled, double blind clinical trial that aims to investigate the effect of transcutaneous electrical nerve stimulation (TENS) and occipital nerve…
- Conditions
- Chronic Cluster Headache, Primary Headache Disorder, Headache, Cluster Headache
- Trial name
- HortONS (NCT05023460)
- Testing
- Paresthesia-free (burst) ONS
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- University of Aarhus
Cluster Headache
Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Cluster Headache
Cluster headache is a primary headache condition characterized by clusters of one-sided, high-intensity pain attacks. The headache may be episodic or chronic. Treatment options are limited and their effects unsatisfactory.
- Trial name
- BASIC (NCT03944876)
- Testing
- Botulinum toxin type A
- Where
- 5 sites in Germany, Italy and 3 more
- Volunteers
- 112 people
- Sponsor
- Norwegian University of Science and Technology
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Cluster Headache, Episodic
Eptinezumab in Participants With Episodic Cluster Headache
The purpose of this study is to evaluate the efficacy of eptinezumab in participants with episodic Cluster Headache (eCH)
- Trial name
- ALLEVIATE (NCT04688775)
- Testing
- Eptinezumab
- Where
- 120 sites in United States, Belgium and 17 more
- Volunteers
- 231 people
- Sponsor
- H. Lundbeck A/S
Chronic Cluster Headache
A 1-year Trial to Inform About Long-term Exposure to Eptinezumab in Participants With Chronic Cluster Headache (cCH)
The main goal of this trial is to inform about long-term safety and tolerability of eptinezumab in participants with chronic cluster headache.
- Trial name
- CHRONICLE (NCT05064397)
- Testing
- Eptinezumab
- Where
- 31 sites in United States, Denmark and 7 more
- Volunteers
- 131 people
- Sponsor
- H. Lundbeck A/S