Clinical trials: CoVid 19 Positive
COVID-19 Pneumonia, Diaphragm Disease
Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in the Positive COVID-19 Patient
Hypoxemic acute respiratory failure is one of the main COVID-19 patients complication that lead to in intensive care hospitalization. This complication determines a variable mortality from 25 to 30%.
- Trial name
- NCT05019313
- Testing
- Evaluation of diaphragmatic contractility by ultrasound
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
HER2-positive Breast Cancer
An Expanded Access Study to Provide at Home Subcutaneous Administration of Pertuzumab and Trastuzumab Fixed-Dose Combination (PH FDC SC) for Patients With HER2-Positive Breast Cancer During the COVID-19 Pandemic
This single arm, multicenter study provides the pertuzumab and trastuzumab fixed-dose combination formulation for subcutaneous injection (PH FDC SC) administered at home by a home health nursing provider for patients with human…
- Trial name
- NCT04395508
- Testing
- Pertuzumab and Trastuzumab Fixed-Dose Combination for Subcutaneous Administration (PH FDC SC)
- Where
- 12 sites in United States
- Sponsor
- Genentech, Inc.
Covid19, Rheumatic Fever
Impact of COVID-19 Pandemic and Social Distancing on Mental Health of Chronic Inflammatory Rheumatism Affected Patients
Recent studies have highlighted the consequences of COVID-19 pandemic and social distancing on mental health of individuals. The aim of this study is to evaluate those consequences within a sample of inflammatory chronic…
- Conditions
- Covid19, Rheumatic Fever, Mental Disorder
- Trial name
- EMOPTION (NCT04798053)
- Testing
- Questionnaire, blood sample and salivary sample
- Where
- 7 sites in France
- Volunteers
- 259 people
- Sponsor
- University Hospital, Bordeaux
Covid19
Early Use of Hyperimmune Plasma in COVID-19
The study assesses the efficacy of early administration of hyperimmune plasma in covid-19 patients who are on CPAP or intubated. Efficacy is measured as a 2 point decrease in the WHO scale
- Trial name
- COV-II-PLA (NCT04721236)
- Testing
- hyperimmune plasma
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- Catherine Klersy
Covid19, Inflammatory Rheumatism
Selection of Patients With Chronic Inflammatory Rheumatism Requiring Management During the COVID-19 Pandemia
The project proposes to evaluate a strategy for prioritizing teleconsultation for patients with chronic inflammatory rheumatic diseases during the COVID-19 pandemia.
- Conditions
- Covid19, Inflammatory Rheumatism, Rheumatoid Arthritis, Spondyloarthritis
- Trial name
- SePaRIC (NCT04806867)
- Testing
- SePaRIC-Covid19 cohort
- Where
- France
- Volunteers
- 918 people
- Sponsor
- University Hospital, Limoges
Covid19
Sensitivity and Specificity of the Roth Test in Patients With COVID-19 Positive
The presence of the described silent hypoxia in subjects diagnosed with COVID19 highlights the need for valid tools to assess respiratory capacity.
- Trial name
- NCT04832828
- Testing
- Roth´s Test
- Where
- Spain
- Volunteers
- 114 people
- Sponsor
- Universidad Autonoma de Madrid
COVID-19 Pneumonia, Cough
Kesuting Syrup in the Treatment of Corona Virus Disease 2019 (COVID-19)
This trial is an exploratory study, aiming to explore the preliminary efficacy and safety of Kesuting Syrup in the treatment of novel coronavirus pneumonia. It is planned to include a total of 200 cases.
- Trial name
- NCT05366231
- Testing
- Kesuting syrup, LianHuaQingWen Granules
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Guizhou Bailing Group Pharmaceutical Co Ltd
COVID-19, Vitamin D Deficiency
The Effects of a Sublingual Sprayable Microemulsion of Vitamin D on Inflammatory Markers in COVID-19 Patients
This placebo-controlled five-day study will be performed on 100 hospitalized COVID-19 patients with vitamin D insufficiency randomized into two groups.
- Trial name
- NCT05502068
- Testing
- Vitamin D 25 (OH) 12000 IU in the form of a sublingual sprayable microemulsion
- Where
- Latvia
- Volunteers
- 102 people
- Sponsor
- Pauls Stradins Clinical University Hospital
COVID-19
CAPTION AI to Minimize Risk of COVID Exposure
Participants scheduled for for an echocardiogram (echo) and being evaluated for, or is positive for COVID-19 will be asked if they would be willing to have their echo done using a new software program on one of the hand-held…
- Trial name
- CAPTION AI (NCT04336774)
- Testing
- Caption AI
- Where
- 2 sites in United States
- Sponsor
- Duke University
Coronavirus Infections
Clinical Performance of the VivaDiag ™ COVID-19 lgM / IgG Rapid Test in Early Detecting the Infection of COVID-19
This study aim to evaluate the immune response of negative patients during a COVID-19 outbreak. Patients are serially tested with a VivaDiag ™ COVID-19 lgM / IgG Rapid Test to evaluate the immune response in negative patients and…
- Trial name
- NCT04316728
- Testing
- VivaDiag™ COVID-19 lgM/IgG Rapid Test
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centro Studi Internazionali, Italy
SARS-CoV 2
IgG/IgM Antibody Test in Patients Who Have Tested Negative or Positive for COVID-19 With the Standard Method of COVID19 Testing.
The purpose of this study is to evaluate point of care SARS-Cov2 Virus IgG/IgM rapid test cassette Clungene test and correlate it with the standard method of testing in inpatients who have tested positive or negative for COVID19.
- Trial name
- NCT04402814
- Testing
- Clungene rapid test cassette
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- Fadi Haddad, M.D.
COVID-19
Photobiomodulation Laser Therapy for COVID-19 Positive Patients With Pulmonary Disease
The aim of this study is to evaluate the effectiveness of MLS laser therapy as a treatment for pulmonary complications due to COVID-19 infection.
- Trial name
- NCT04391712
- Testing
- MLS Laser, Regular Inpatient Medical Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lowell General Hospital
Covid19 Positive Patients
Role of Interleukin-6 and Procalcitonin as Novel Inflammatory Biomarkers in Evaluating COVID 19 Disease Severity - an Experience at CMH Quetta
Serum Interleukin-6 and Procalcitonin of 100 consenting COVID 19 positive patients from April 2020 - May 2021 were assessed at Pathology department CMH Quetta and the results were correlated with severity of lung involvement on…
- Trial name
- NCT04945811
- Testing
- Interlukein 6 and procalcitonin serum levels
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- FARAH AFZAL
Covid19
SLV213 Treatment in Ambulatory COVID-19 Patients
This Phase 2a trial recruits adult ambulatory patients who have been determined to be COVID-19 positive. The study drug SLV213 will be administered to examine its safety, tolerability and provide assessment of its effect on…
- Trial name
- NCT04843787
- Testing
- SLV213
- Volunteers
- 81 people
- Sponsor
- Kenneth Krantz, MD, PhD
Burnout, Stress, Emotional
Effect of Positive Attitudes on Behavior and Wellness
The COVID-19 pandemic has undoubtedly elevated levels of stress to people all over the globe, but none more than to the providers on the front-line.
- Trial name
- TEAM-ICU (NCT04441632)
- Testing
- Positive feedback
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Lopinavir/Ritonavir for the Treatment of COVID-19 Positive Patients With Cancer and Immune Suppression in the Last Year
This phase II trial studies how well lopinavir/ritonavir works in treating COVID-19 positive patients with cancer and a weakened immune system (immune-suppression) in the last year and have mild or moderate symptoms caused by…
- Conditions
- Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Symptomatic COVID-19 Infection Laboratory-Confirmed
- Trial name
- NCT04455958
- Testing
- Lopinavir/Ritonavir, Questionnaire Administration
- Sponsor
- OHSU Knight Cancer Institute
COVID-19 Pandemic
Indicators of Neuronal Insult in Newborns of COVID-19 Positive Mothers.
The coronavirus disease (COVID- 19) is now a global pandemic that was first reported in China (Wuhan) in December of 2019. Multiple placental abnormalities including fetal and maternal vascular malperfusion have been described in…
- Trial name
- NCT05175638
- Testing
- Gene Expression
- Volunteers
- 50 people
- Sponsor
- Assiut University
COVID-19, COVID
Early CPAP in COVID-19 Confirmed or Suspected Patients
There is surge in COVID infected patients in New York City with a shortage of hospital beds, ICU beds and ventilators. Strategies to reduce the need for all of the above are immediately needed.
- Conditions
- COVID-19, COVID, Coronavirus
- Trial name
- PAP-COVID (NCT04390191)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Covid19
Semen Analysis Changes in Covid-19 Positivepatients
The viral pandemic of the coronavirus disease 2019 (COVID-19), generated by a novel mutated severe acute respiratory syndrome coronavirus (SARS-CoV-2), has become a serious worldwide public health emergency, evolving…
- Trial name
- NCT04595240
- Testing
- semen analysis
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Covid19
Investigational Performance Evaluation of the Nanomix eLab® COVID-19 Rapid Antigen Panel With Samples From COVID-19 Positive and Negative Human Subjects
Prospective samples will be collected to evaluate the agreement between a EUA RT-PCR test as the comparator method against the Nanomix eLab® system.
- Trial name
- NCT04667442
- Testing
- Nanomix eLab® COVID-19 Rapid Antigen Panel (non-interventional)
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Nanomix