Clinical trials: Coagulopathy, Consumption
Sepsis, Blood Coagulation Disorders
Analysis of the Coagulopathy Developed by COVID-19 Infected Patients
Increased D-dimers at admission of COVID-19 infected patients entering hospital due to a severe disease is a risk factor for death.
- Conditions
- Sepsis, Blood Coagulation Disorders, Thrombin, Disseminated Intravascular Coagulation
- Trial name
- COVID-TGT (NCT04356950)
- Testing
- Thrombin generation test assay, Fibrin generation markers assays
- Where
- 4 sites in France
- Volunteers
- 175 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hemophilia A
A Study to Learn More About Treatment With Damoctocog Alfa Pegol, How it is Used in Every Day Practice ("Real-World"), and How Satisfied People Who Receive Damoctocog Alfa Pegol Are in United States (US) Hemophilia Treatment Centers
People with hemophilia A do not have enough of a protein found naturally in the blood called "clotting factor 8", also known as FVIII. This protein helps the blood to clump together to prevent and stop bleeding.
- Trial name
- REAL (NCT05395858)
- Testing
- No intervention
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Bayer
Sepsis, Disseminated Intravascular Coagulation
Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation
The primary objective of this study is to estimate the efficacy of unfractionated heparin(UFH) on ICU mortality in severe sepsis with suspected DIC.The Second objective is to estimate the effect of UFH on 28-day mortality,and the…
- Trial name
- NCT02654561
- Testing
- Heparin Sodium, Saline
- Where
- 17 sites in China
- Volunteers
- 600 people
- Sponsor
- China Medical University, China
Disseminated Intravascular Coagulation (DIC)
An Open-label Study of KW-3357
The purpose of this study is to evaluate the efficacy and safety of KW-3357 compared to plasma-derived antithrombin using multi-center, open-label, parallel-group, comparative method in patients with Disseminated Intravascular…
- Trial name
- 3357-004 (NCT01384903)
- Testing
- KW-3357, Plasma-derived antithrombin
- Where
- Japan
- Volunteers
- 221 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Shock, Septic
Significance of Disseminated Intravascular Coagulation Score in Mortality for Children With Shock
Evaluates whether the DIC score, as defined according to the International Society of Thrombosis and Hemostasis guidelines is associated with mortality in Children with shock and DIC
- Trial name
- NCT06581172
- Testing
- D_dimer
- Volunteers
- 80 people
- Sponsor
- Assiut University
Hematologic Neoplasms, Solid Tumor Metastatic Cancer Advanced Cancer
Role of Fibrinolytic Activity in Neoplastic Pathologies Complicated by Coagulopathy
The aim of this research is to measure fibrinolytic activity in neoplastic pathologies in order to provide preliminary data on which to base a future, larger-scale study to determine predictive markers of complication in order to…
- Conditions
- Hematologic Neoplasms, Solid Tumor Metastatic Cancer Advanced Cancer, Disseminated Intravascular Coagulation
- Trial name
- NEO-COAG (NCT07234630)
- Testing
- An additional volume of blood will be drawn as part of routine follow-up care
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France