Clinical trials: Cochlear
Hearing Loss, Conductive
Comparative Study of Two Surgical Techniques for Soft Tissue Healing and Implant Stability of Cochlear BI300 Implants.
The study compares two different operative techniques for placement of the Cochlear Bi300 implant to be used for bone anchored hearing aid.
- Trial name
- NCT01699620
- Testing
- BAHA implant insertion
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- Aarhus University Hospital
Hearing Loss
Evaluation of a Revised Indication for Determining Adult Cochlear Implant Candidacy
The Sponsor values the progression of hearing healthcare practice and acknowledges a need for re-evaluation of indications for determining adult cochlear implant candidacy.
- Trial name
- NCT01337076
- Testing
- cochlear implant
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cochlear
Sensorineural Hearing Loss, Bilateral
Speech Perception of a Tonotopy-based Fitting for Cochlear Implant Recipients for 6 Months With Conventional Setting
Main objective: Compare speech recognition in noise with tonotopic fitting (FS4T) and with conventional non-tonotopic fitting (FS4noT) in adult patients implanted for 6 months with a MED-EL cochlear implant with FS4noT strategy.
- Trial name
- NCT06723262
- Testing
- Tonotopic cochlear implant fitting FS4T
- Where
- France
- Volunteers
- 25 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Cochlear Implants, Evoked Potentials, Auditory
Optimization of Cochlear Implant MAP-parameters in Children
This project will complete a long-term follow up for children that have received cochlear implants (CI) early in life and had their CI's programmed based on objective measurements.
- Conditions
- Cochlear Implants, Evoked Potentials, Auditory, Child, Disabilities Hearing
- Trial name
- NCT03694340
- Testing
- Re-programming of cochlear implant
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Deafness
Investigating Auditory Processing in the Users of Auditory Brainstem and Cochlear Implants
This is a basic investigational research study conducted with hearing impaired adults and children who use cochlear implant or auditory brainstem implant (ABI) devices.
- Trial name
- NCT05810220
- Testing
- Electrode-Neural Interface
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Cochlear Implants, Hearing Loss, Sensorineural
Clinical Trial to Compare Two Surgical Approaches to the Cochlea
This is a prospective multicenter multinational randomized control trial. The duration of the study for the individual patient will be approximately 1 year (pre-operative assessments, 1 week, 3 months and 12 months follow-up…
- Trial name
- BULLS-I (NCT06453343)
- Testing
- Surgical approach: cochleostomy or extended round window
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
Deafness
Assessment of Bimodal Contribution in Adult Cochlear Implant Users
To evaluate the combination of electric hearing through Cochlear Implant and acoustic hearing through hearing aid in bimodal users with moderate-to-severe hearing loss in the non-implanted ear.
- Trial name
- NCT02331017
- Testing
- Speech perception tests and self-rating questionnaire
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Bnai Zion Medical Center
Unilateral Acoustic Neuroma, Meniere's Disease
Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical Approach
The goal of this project is to determine whether subjects who have undergone labyrinthectomy or a translabyrinthine surgical approach as the treatment for vestibular schwannoma or Meniere's disease benefit from cochlear…
- Trial name
- NCT02309099
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Hearing Loss, Cochlear
Effects of Pulses on Loudness
The aim of this study is to investigate the effect of varying additional factors on loudness summation in Neuro Zti Cochlear Implant users.
- Trial name
- EfPuL (NCT04010721)
- Testing
- Experiment 1, Experiment 2:, Experiment 3
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Oticon Medical
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
A Monocentric Study Evaluating Pupillometry as an Objective Measurement for CI Fittings
This trial is a monocentric, prospective and controlled study of the pupil response to detect hearing threshold and comfortable loudness of normal-hearing (NH) and CI-subjects.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Bilateral, Cochlear Hearing Loss, Hearing Loss, Cochlear
- Trial name
- PupillOM (NCT05586555)
- Testing
- Pupillometry (Eve-tracking measurements)
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oticon Medical
Profound Deafness
Optimization of Cochlear Implant Fitting in Patients With Functional Contralateral Hearing Using an Evolutionary Algorithm.
360 million people worldwide suffer from disabling hearing loss. The prevalence of hearing impairment, all stages combined, in the French population is 7% (4 million people), of which 9% have severe impairment and 3% have…
- Trial name
- Algo Fréq (NCT04888143)
- Testing
- questionnaires, Evolutionary algorithm
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Sensorineural Hearing Loss (Disorder)
Single-sided Deafness and Cochlear Implants
As the left and right hemisphere are specialized for different auditory tasks, the proposed study aims at demonstrating different consequences of right or left-sided deafness for the affected individual.
- Trial name
- NCT01749592
- Testing
- cochlear implant
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Hearing Loss, Hearing Disorders
Validation of a Smartphone-Based Hearing-in-Noise Test (HearMe)
The purpose of this project is to validate a quick, easy-to-use and administer smartphone hearing-in-noise test. The Hearing-in-Noise Test (HINT) measures an individual's ability to hear speech in quiet and in noise.
- Conditions
- Hearing Loss, Hearing Disorders, Hearing Abnormality, Hearing Disability
- Trial name
- HearMe (NCT03429777)
- Testing
- HearMe Smartphone Application
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron is conducting a study of an investigational new drug called DB-OTO. DB-OTO is a gene therapy that is being developed to treat pediatric and adult participants who have severe-to profound and profound hearing loss due to…
- Trial name
- CHORD (NCT05788536)
- Testing
- DB-OTO
- Where
- 17 sites in United States, Germany and 3 more
- Volunteers
- 36 people
- Sponsor
- Regeneron Pharmaceuticals
Hearing Loss, High-Frequency
Hybrid Cochlear Implants in Severe to Profound Adults, Children, and Adolescents
The purpose of this study is to determine if adults and children with residual low-pitch hearing in the severe hearing loss range can develop improved speech perception by combining their residual acoustic hearing with electrical…
- Trial name
- NCT01975571
- Testing
- Cochlear® Nucleus™ Hybrid L24, Cochlear® Nucleus™ Hybrid S12
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bruce J Gantz
Hearing Loss, Genetic Disease
Auditory Restoration and Outcomes After Gene Therapy and Cochlear Implantation: a PRospective Cohort Analysis (AURORA)
This cohort study aims to explore the trends and differences in multidimensional perceptual levels of patients after cochlear implants or gene therapy, as well as to comprehensively assess the efficacy of gene therapy for…
- Conditions
- Hearing Loss, Genetic Disease, Speech Perception
- Trial name
- NCT06237790
- Where
- 6 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Vestibular Schwannoma, Acoustic Neuroma
Auditory Nerve Test System During Vestibular Schwannoma Resection
The Auditory Nerve Test System (ANTS) is a novel device that stimulates the auditory nerve much like a cochlear implant. The purpose of this study is to demonstrate feasibility of the ANTS during translabyrinthine surgery for…
- Conditions
- Vestibular Schwannoma, Acoustic Neuroma, Sensorineural Hearing Loss, Asymmetric Sensorineural Hearing Loss
- Trial name
- ANTS (NCT04241679)
- Testing
- Auditory Nerve Test System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Hearing Loss
Neuroplastic Changes Seen in Cochlear Implants With Preserved Hearing
Investigators hope to study patients with 1 cochlear implant and who have had hearing preservation surgery and compare the changes in the brain of these patients with normal hearing patients by doing a scan of the brain when…
- Trial name
- NCT02407587
- Testing
- cochlear implants
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Infection, Implant Infection
A New Predictor Marker for Cochlear Implants Infection
Introduction: Surgical site infections associated with the cochlear implant can have serious consequences. Although advances in surgical techniques reduce these complications, it may be necessary to remove a device that works as…
- Conditions
- Infection, Implant Infection, Cochlear Hearing Loss
- Trial name
- NCT04120181
- Testing
- There is no intervention.
- Volunteers
- 13 people
- Sponsor
- Selcuk University
Deafness
Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces
Despite the success of cochlear implants, devices surgically placed in the inner ears of patients with severe hearing loss, there remains substantial variability in the overall speech perception outcomes for the children and…
- Trial name
- NCT05867173
- Testing
- Experimental Speech Processing Strategy
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary