Clinical trials: Cochlear
Hearing Loss, Partial Deafness
Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults With Partial Deafness
The purpose of this feasibility study is to evaluate whether low-frequency acoustic hearing sensitivity can be preserved in newly implanted adults with partial deafness (considerable low frequency acoustic hearing profiles with…
- Conditions
- Hearing Loss, Partial Deafness, Hearing Disorders, Ear Diseases
- Trial name
- NCT02189798
- Testing
- HiRes 90K™ Advantage implant with HiFocus™ Mid-Scala electrode, EAS sound processor
- Where
- 11 sites in United States
- Volunteers
- 67 people
- Sponsor
- Advanced Bionics
Deafness, Hearing Loss
Speech Perception Performance With Gap-interleaved Stimulation Paradigms
Cochlear implants (CI) are used to help patients with severe to profound hearing loss regain auditory perception by electrical stimulation of the auditory nerve.
- Trial name
- NCT03937388
- Testing
- Cochlear stimulation strategy including time-fixed gaps
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Angelica Perez Fornos
Cochlear Hearing Loss, Cochlear Trauma
Using Electrocochleography During Cochlear Implantation of the Neuro Zti.
The main objective of this study is to evaluate the correspondence between eCochG and residual hearing by adding two modifications.
- Trial name
- PIC-22_eCoN (NCT04651660)
- Testing
- Neuro Cochlear Implant System
- Sponsor
- Oticon Medical
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population
This study aims to evaluate the safety and efficacy of cochlear implantation for adults with bilateral sensorineural hearing loss who currently do not meet the FDA-approved indications for cochlear implantation.
- Trial name
- ACE (NCT06293482)
- Testing
- Cochlear™ Nucleus® System
- Where
- 9 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cochlear
DFNB9, Cochlear Implantation
Safety, Tolerability, Efficacy of EA0010 in OTOF Patients With CI
This study will evaluate the safety, tolerability, and efficacy of EA0010 injection in patients with OTOF-related hearing loss who have already undergone cochlear implantation.
- Trial name
- NCT07752888
- Testing
- EA0010 Injection
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Shanghai EmayGene Technology Co., Ltd
Hearing Loss
Clinical Investigation of the Nucleus® CI532 Cochlear Implant
The aim of this study is to investigate the clinical benefit for patients implanted with the Nucleus® CI532 cochlear implant and to demonstrate the atraumatic nature of the electrode design.
- Trial name
- NCT02392403
- Testing
- Nucleus CI532 cochlear implant
- Where
- 8 sites in Australia, France and 2 more
- Volunteers
- 45 people
- Sponsor
- Cochlear
Cochlear Implants
Remote Care: The Future of Cochlear Implants
The purpose of this study is to see if remote programming visits for cochlear implants are possible.
- Trial name
- NCT04721327
- Testing
- remote CI programming
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Deafness
Prospective Study of Round Window Versus Cochleostomy Approach to CI Surgery
To the investigators' knowledge, no clinical study has prospectively investigated the relationship between surgical insertion technique, intracochlear electrode location, and postoperative hearing outcomes.
- Trial name
- NCT02466763
- Testing
- Cochlear implant surgery
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Deafness
Cerebral Activation and Bilateral Stimulation by Cochlear Implantation in Bilateral Deaf Adults
The primary objective to this study is to describe bilateral auditory information processing in profoundly deaf patients with bilateral cochlear implants compared with normal hearing patients.
- Trial name
- NCT02904187
- Testing
- Positron Emission Tomography (PET), Electroencephalogram (EEG)
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Bilateral Cochlear Aplasia, Bilateral Cochlear Nerve Deficiency
Feasibility Study of Auditory Brainstem Implant in Young Children
Current treatment options for bilateral profoundly deaf children, diagnosed with inner ear anatomical abnormalities are limited, and in the case of absent cochleas, non-existent.
- Conditions
- Bilateral Cochlear Aplasia, Bilateral Cochlear Nerve Deficiency, Bilateral Cochlear Ossification Secondary to Meningitis
- Trial name
- NCT01850225
- Testing
- Auditory brainstem implant
- Where
- United States
- Sponsor
- House Research Institute
Diabetes Mellitus Type 2 in Obese
Cochlear-Vestibular Ganglion (CVG) in Newly Diagnosed Type 2 Diabetes Patients
The proposed study is an integrative scientific undertaking, reflecting the input of experts in the behavioral sciences, mHealth technology, computational biology, endocrinology, biochemistry, and nutrition.
- Trial name
- NCT02668328
- Testing
- Social Cognitive Theory Tailored Behavioral Intervention
- Sponsor
- NYU Langone Health
Severe Unilateral Sensorineural Hearing Loss
Cochlear Implantation Among Adults and Older Children With Unilateral or Asymmetric Hearing Loss
Do adults and children over 7 years of age with unilateral or assymetric hearing loss benefit from cochlear implantation on the worst hearing side.
- Trial name
- CI and SSD (NCT02105441)
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Deafness
Intraoperative Electrically-evoked ABRs in Patients Undergoing Vestibular Schwannoma Surgery
This is a study of the feasibility of activating the auditory system by an electrode in direct contact with the cochlear nerve.
- Trial name
- NCT05248113
- Testing
- Electrical stimulation of cochlear nerve
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Irvine
Cochlear Implant Users
This Clinical Investigation Assesses the Safety and Performance of a New Beamformer for MED-EL Cochlear Implant Recipients.
Cochlear implants help individuals with hearing loss by delivering electrical signals directly to the auditory nerve, bypassing damaged parts of the ear.
- Trial name
- M11S3 (NCT07213505)
- Testing
- Testing new front-end features
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Hard of Hearing
Cochlear Implants : Influence of Microphone Aging and Dirtying
Cochlear implant microphones are subject to aging and dirtying. The evolution may affect their efficiency. Several signal coding strategies are used in cochlear implants and their behaviour may be more or less affected by the…
- Trial name
- NCT02369718
- Testing
- Listening to 12 Fournier's lists of words, Listening to 48 Fournier's lists of words
- Where
- France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Deafness Unilateral, Deafness, Bilateral
Cochlear Implant Electrostimulation and the Influence on the Vestibular Organ
There is evidence that the sensor function of the utricle in patients with bilateral labyrinthine dysfunction (bilateral vestibulopathy) may improve balance under the influence of high frequency basal stimulation of the cochlea.
- Conditions
- Deafness Unilateral, Deafness, Bilateral, Deafness Congenital, Deafness, Acquired
- Trial name
- NCT05073796
- Testing
- Cochlea Implant
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- RWTH Aachen University
Developmental Cochlear Nerve Deficiency, Acquired Cochlear Nerve Deficiency
Auditory Brainstem Implantation in Young Children
To purpose of this feasibility study is to demonstrate the safety and efficacy of the Nucleus 24 Multichannel Auditory Brainstem Implant (ABI, Cochlear Corp, Sydney, AUS) in children without the diagnosis of neurofibromatosis…
- Conditions
- Developmental Cochlear Nerve Deficiency, Acquired Cochlear Nerve Deficiency, Cochlear Aplasia, Post-meningitis Cochlear Ossification
- Trial name
- NCT01904448
- Testing
- Auditory Brainstem Implantation in Children
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Intracranial Pressure, Traumatic Brain Injury
NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit
In clinical practice, intracranial pressure (ICP) represents a key parameter for diagnosing and treating several conditions. Physicians having to manage cases of head trauma, stroke and hydrocephalus need to assess the time…
- Conditions
- Intracranial Pressure, Traumatic Brain Injury, Stroke, Intracranial Hemorrhages
- Trial name
- MINIPIC REA (NCT01685476)
- Testing
- Echodia® hand-held equipment
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Long Term Neurobehavioral Effects
The Neurobehavioral Effects of Anesthetics on Infants With Hearing Impairment
The long-term effect of general anesthesia on developing brain is the focus of clinicians when infants exposed to general anesthesia for a long time during operation.
- Trial name
- NCT04255485
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Hearing Loss
CROS Application in CI
Bilateral profound sensorineural hearing loss (PSNHL) is often treated with Cochlear Implants. The majority of bilaterally deafened patients, however, often only receive a unilateral cochlear implant (CI), with resultant…
- Trial name
- CROS (NCT03243097)
- Testing
- Phase I - Standard Microphone Cros Input, Phase II - Automatic directional microphone Cros Input, Phase III - No Cros Input
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami