Clinical trials: Cochlear
Telerehabilitation
Effect Of Music Integrated Phonological Awareness Program On Preschool Cochlear Implant Users
The aim was to observe the effect of the music integrated phonological awareness program on preschool cochlear implant users and to compare the phonological awareness skills of the study group with the control group before and…
- Trial name
- NCT05543031
- Testing
- Music-Integrated Phonological Awareness training program, Spectral-Temporally Modulated Ripple Test (SMRT), The Phonological Awareness Scale of Early Childhood Period (PASECP)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Tractography, Cochlear Implant
Predictive Study on Hearing Rehabilitation After Cochlear Implant
The aim of this study is to display the predictive factors of hearing rehabilitation after cochlear implant surgery in severely to profoundly deaf adults.
- Conditions
- Tractography, Cochlear Implant, Magnetic Resonance Imaging, Hearing Rehabilitation
- Trial name
- NCT06086041
- Testing
- cochlear implant
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Grenoble
Sensorineural Hearing Loss
Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
This is a randomized, double-blind study of PIPE-505, or placebo, in subjects with hearing loss associated with speech-in-noise impairment.
- Trial name
- NCT04462198
- Testing
- PIPE-505
- Where
- 8 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Contineum Therapeutics
Severe to Profound Hearing Loss
Impact of Robotic Cochlear Implantation on Hearing Performance in Noise
The purpose of this study is to compare two methods of cochlear implantation : conventional manual insertion versus robot-assisted in order to verify whether robotic insertion provides better performance in the noisy environment.
- Trial name
- ROBOT-IC-BRUIT (NCT06248398)
- Testing
- Surgery with RobOtol®, Conventional manual surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cochlear Implant Users, Cochlear Hearing Loss
Effects of Binaural Hearing on Listening Effort and Cognitive Development in Mandarin-speaking Children With Cochlear Implants
The goal of this observational study is to learn how listening effort affects brain development and daily life in school-aged children (ages 6-18) who use cochlear implants (CIs), which are electronic devices surgically placed in…
- Trial name
- NCT07509788
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Xiong hao
Cochlear Implant, Severe-Profound Hearing Loss
Bimodal, CROS and Severe Profound Hearing Loss Study
The study will involve the comparison of three groups with severe-profound hearing loss. Patients with a Cochlear Implant only, patients with a cochlear implant and Hearing Aid, and finally patients with two hearing aids.
- Conditions
- Cochlear Implant, Severe-Profound Hearing Loss, Hearing Loss, Bilateral, Hearing Loss, Cochlear
- Trial name
- NCT04222296
- Testing
- Fitting strategy of cohlear implant of hearing aid
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
OTOF Gene Mutation, DFNB9
A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations
This study intends to assess safety, tolerability, and efficacy of SENS-501 in children between the ages of 6-31 months with pre-lingual hearing loss due to a mutation in the Otoferlin gene.
- Conditions
- OTOF Gene Mutation, DFNB9, Congenital Deafness, Hearing Disorders
- Trial name
- AUDIOGENE (NCT06370351)
- Testing
- SENS-501 administration
- Where
- 2 sites in Australia, France
- Volunteers
- 12 people
- Sponsor
- Sensorion
Sensorineural Hearing Loss
Clinical Evaluation of a Cochlear Implant System
The primary objective of this study is to assess the usability of a Cochlear implant system.
- Trial name
- NCT03467399
- Testing
- Nucleus 7 Cochlear Implant System
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cochlear
Cochlear Nerve Disease
Longitudinal Study Of The Evoked Compound Action Potential Measured In Children Cochlear Implant Users
Introduction: In Cochlear Implant (CI) users, the recording of the electrically evoked compound action potential (ECAP) of the auditory nerve represents an option to assess changes in auditory nerve responses and the interaction…
- Trial name
- ECAP (NCT00725998)
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hearing Loss, Hearing Loss, Sensorineural
Single-sided Deafness and Cochlear Implantation
This observational study evaluates the effects of cochlear implantation in patients with deafness in one ear.
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Unilateral, Hearing Loss, Sudden
- Trial name
- NCT05052944
- Testing
- Cochlear implantation
- Where
- 5 sites in United States
- Volunteers
- 78 people
- Sponsor
- Johns Hopkins University
Cochlear Hearing Loss, Hearing Loss
Remote Evaluation of the Naída CI M90 (Marvel) Sound Processor
Within-subject comparison. Remotely Evaluating latest Advanced Bionics Marvel Sound Processor for cochlear implants, from two adult groups.
- Trial name
- NCT05007886
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hearing Loss
CHANGE Feasibility Study
The purpose of the feasibility study is to examine audiological outcomes (audiometry and speech perception) and safety (adverse events and adverse device effects) with the Nucleus CI532 cochlear implant in group of adult subjects…
- Trial name
- CLTD5626 (NCT02671032)
- Testing
- Nucleus CI532 cochlear implant
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Cochlear
Hearing Loss, Cochlear Implantation
Same-Day Cochlear Implant Activation (SDA-CI)
This randomized controlled study investigates whether activating a cochlear implant on the day of surgery (same-day activation) leads to faster stabilization of cochlear implant programming compared with the current standard…
- Trial name
- SDA-CI (NCT07681830)
- Testing
- Same-Day Cochlear Implant Activation, Standard Day-14 Cochlear Implant Activation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Tinnitus
Effects of CI on Tinnitus and Its Symptoms
Abnormal activity in the central auditory system is the cause of subjective experience of tinnitus. Electrical stimulation can inhibit the abnormal activity of auditory related neurons in patients with tinnitus.
- Trial name
- NCT05453019
- Testing
- Cochlear Implant
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Unilateral Cochlear Implants, Bilateral Cochlear Implants
Impact of Binaural Audition on Postural Performance and Orientation
This is a prospective research study talking place at University hospital of Dijon and requiring the inclusion of 20 healthy subjects, 10 patients with unilateral cochlear implants and 10 patients with bilateral cochlear implants…
- Trial name
- AUDIPIC (NCT03201328)
- Testing
- Audio-vestibular examination, Videonystagmoscopic study, Posturographies study
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Cochlear Implants, Bilateral Sensorineural Hearing Loss
Assessing the Effect of Computer-based Auditory Training on Adult Cochlear Implant Speech and Quality-of-life Outcomes
The purpose of this study is to compare the effectiveness of a free computer-based auditory training program, Sound Success (Advanced Bionics, Valencia, CA), with the current standard of care of patient-directed auditory training…
- Trial name
- NCT06607146
- Testing
- Sound Success, Standard of Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Sensorineural Hearing Loss, Tinnitus
Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing Loss
The HEAR-RESTORE study is an exploratory clinical research program designed to evaluate new diagnostic and regenerative approaches for individuals experiencing inner ear injury, tinnitus, and temporary or permanent hearing loss.
- Conditions
- Sensorineural Hearing Loss, Tinnitus, Acoustic Trauma, Inner Ear Injury
- Trial name
- HEAR-RESTORE (NCT07472023)
- Testing
- Audiologic Monitoring, Investigational Regenerative Pharmacologic Therapy, Stem Cell Regenerative Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Truway Health, Inc.
Hearing Loss
Scalar Localization Cochlear Electrode Array Using 64 Slice CT
Insertion of electrode array in scala vestibuli, rather than the preferred location within scala tympani, leads to loss of native hearing in those patients with isolated high-frequency hearing loss undergoing cochlear…
- Trial name
- NCT00587262
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Language Development
Language Environment in Children With Cochlear Implants
The Language Environment Analysis (LENA) system is a specific tool for the language environment analysis. Children aged from 18 months to 6 years old, with cochlear implants (CIs), wear an electronic device during a day and their…
- Trial name
- ISLODA (NCT02853786)
- Testing
- LENA and advice, LENA without advice
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Hearing Loss, Sensorineural, Deafness
Long Latency Auditory Evoked Potentials (P300) Outcomes in Patients With Unilateral Cochlear Implants
Bilateral severe to profound hearing loss is a socially disabling handicap. Cochlear implants can be used to improve hearing in cases where conventional hearing aids are not effective.
- Trial name
- NCT03352154
- Testing
- P300 - Auditory long latency potential
- Volunteers
- 21 people
- Sponsor
- University of Sao Paulo