Clinical trials: Cochlear, open to volunteers
Otolaryngological Diseases Requiring Mastoidectomy, Middle Ear Surgery, Endolymphatic Sac Surgery, Cochlear Implant, Labyrinthectomy, Petrous Apex Lesions, Facial Nerve Surgery, and Lateral Skull Base Tumors
AI Recognition of Important Structures in Otolaryngological Surgery
Developing a system for artificial intelligence to recognize anatomical landmarks in otolaryngological surgery, enabling real-time tracking of critical temporal bone structures during surgery.
- Trial name
- NCT06726551
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Deafness, Bilateral
Study of the Role of Top-down Processes in Neuronal Reorganization and Recovery From Sensory Loss: an Exploratory Behavioral and Electroencephalographic Study in Cochlear-supported Deaf Patients
This study posits that central top-down processes (attention, inhibition), marked by alpha oscillations in EEG, play a key role.
- Trial name
- REASCENT (NCT07500909)
- Testing
- neurophysiological assessment, Cognitive, behavioral and quality of life assessment
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Bilateral Cochlear Implants, Hearing Loss, Bilateral
Spatial Cues, Task Demands, and Auditory Selective Attention
Understanding speech in restaurants and other noisy environments is the most common complaint from the more than 60 million Americans with hearing impairment.
- Conditions
- Bilateral Cochlear Implants, Hearing Loss, Bilateral, Healthy
- Trial name
- NCT07765186
- Testing
- Existing bilateral cochlear implants, Normal Hearing Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hearing Loss
Opto-electrical Cochlear Implants
Neural stimulation with photons has been proposed for a next generation of cochlear implants (CIs). The potential benefit of photonic over electrical stimulation is its spatially selective activation of small populations of…
- Trial name
- oCI (NCT05110183)
- Testing
- electrical stimulation, optical stimulation, combined optical and electrical stimulation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Cochlear Implants, Bilateral Sensorineural Hearing Loss
Assessing the Effect of Computer-based Auditory Training on Adult Cochlear Implant Speech and Quality-of-life Outcomes
The purpose of this study is to compare the effectiveness of a free computer-based auditory training program, Sound Success (Advanced Bionics, Valencia, CA), with the current standard of care of patient-directed auditory training…
- Trial name
- NCT06607146
- Testing
- Sound Success, Standard of Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Cochlear Implantation, Sensorineural Hearing Loss
Retrospectively Investigating Longitudinal Outcomes in MED-EL SONATA 2 Cochlear Implant Recipients.
MED-EL Cochlear Implants (CI) provide auditory sensations via electrical stimulation of the auditory pathways for severely to profoundly hearing-impaired individuals who obtain little or no benefit from acoustic amplification in…
- Trial name
- LORIS (NCT07697911)
- Testing
- Transfer of data of SONATA 2 cochlear implant recipients
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Hearing Loss, Binaural, Cochlear Implantation
Mi2000 TICI - Post-market Implantation Study
This Post-Market Clinical Follow-up (PMCF) investigation aims to further collect evidence on safety and performance of the Mi2000 TICI.
- Trial name
- TUPIS (NCT07897318)
- Testing
- Cochlear Implantation
- Volunteers
- 22 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Cochlear Synaptopathy
A Study Testing the Safety and Possible Benefits of an Ear Injection of a New Compound, Paliroden, in People With Type 2 Diabetes Who Have Difficulty Understanding Speech in Noisy Situations
Like retinopathy, neuropathy and nephropathy, sensorineural hearing loss is a common and underserved complication of uncontrolled diabetes.
- Trial name
- RESPLAND (NCT07472907)
- Testing
- CIL001 (Paliroden)
- Volunteers
- 135 people
- Sponsor
- Cilcare SAS
Severe to Profound Hearing Loss
Impact of Robotic Cochlear Implantation on Hearing Performance in Noise
The purpose of this study is to compare two methods of cochlear implantation : conventional manual insertion versus robot-assisted in order to verify whether robotic insertion provides better performance in the noisy environment.
- Trial name
- ROBOT-IC-BRUIT (NCT06248398)
- Testing
- Surgery with RobOtol®, Conventional manual surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Auditory Perception; Abnormal, Hearing Loss, Sensorineural
Listening Effort in Cochlear Implant Users
People with hearing loss experience extra effort when listening, which can lead to severe psychological barriers to communication and social participation.
- Conditions
- Auditory Perception; Abnormal, Hearing Loss, Sensorineural, Hearing Loss
- Trial name
- NCT06516575
- Testing
- sentence manipulations
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Performance Prediction
Cochlear-Implant-Performance-Prediction
Despite improved technology, many cochlear implant (CI) recipients still struggle to understand speech in noise (SIN). Because the bottom-up acoustic signal generated by the implant is distorted relative to normal-hearing…
- Trial name
- NCT07564388
- Testing
- cochlear implant user performance prediction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cochlear Implant Users
Investigating the Acceptance and Performance of Low Energy Audio Streaming in Nucleus 8 and Kanso 3 Sound Processors by Experienced Cochlear Implant Users
This study aims to investigate acceptance and performance of the Bluetooth Low Energy Audio-enabled (LE Audio) firmware in the Nucleus 8 Processing Unit, Kanso 3 Nexa Sound Processor, and the Kanso 3 Sound Processor.
- Trial name
- STREAM (NCT07262827)
- Testing
- Nucleus 8 Sound Processor streaming via MultiMic+, Nucleus 8 Sound Processor microphones, Nucleus 8 Sound Processor streaming via Roger 20
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Cochlear
Deafness
Investigating Auditory Processing in the Users of Auditory Brainstem and Cochlear Implants
This is a basic investigational research study conducted with hearing impaired adults and children who use cochlear implant or auditory brainstem implant (ABI) devices.
- Trial name
- NCT05810220
- Testing
- Electrode-Neural Interface
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Cochlear Implant Users
Early Cochlear Implant Use
This observational study will examine newly activated cochlear implant users and determine whether their abilities to discern simple sounds change and relate to improved speech perception.
- Trial name
- NCT07114744
- Testing
- Take home tests
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Hearing Loss, Adult-Onset, Speech Intelligibility
Cochlear Implant Speech in Noise Processing
The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.
- Conditions
- Hearing Loss, Adult-Onset, Speech Intelligibility, Hearing Loss, Extreme
- Trial name
- NCT06860152
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Craig D. Workman, PhD
Hearing Loss, Cochlear Implantation
Same-Day Cochlear Implant Activation (SDA-CI)
This randomized controlled study investigates whether activating a cochlear implant on the day of surgery (same-day activation) leads to faster stabilization of cochlear implant programming compared with the current standard…
- Trial name
- SDA-CI (NCT07681830)
- Testing
- Same-Day Cochlear Implant Activation, Standard Day-14 Cochlear Implant Activation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Vestibulopathy, Moderate to Severe Hearing Loss
A Study to Evaluate the Safety and Performance of a Vestibular Implant in Adults to Provide Balance Restoration
The main aim of this study is to understand if an experimental vestibular implant system can improve balance performance. The system consists of a vestibular implant combined with a cochlear implant sound processor and…
- Conditions
- Vestibulopathy, Moderate to Severe Hearing Loss, Normal Hearing, Balance Deficits
- Trial name
- BionicVEST2 (NCT06805175)
- Testing
- vestibular implant
- Where
- 3 sites in Belgium, Spain
- Volunteers
- 18 people
- Sponsor
- Cochlear
Hearing Loss
fNIRS in Pediatric Hearing Aids
Pilot phase. Monocentric, non-controlled, non-randomized, open-label study evaluating the capacity of the functional near-infrared functional neuroimaging (fNIRS) technique to translate temporal cortical activity in response to a…
- Trial name
- FNIRS (NCT04696835)
- Testing
- speech audiometry
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille
Deafness
Improving Cochlear Implant Outcomes Through Modeling and Programming Strategies Based on Human Inner Ear Pathology
Cochlear implants are devices placed in the inner ear through surgery to help people with severe to profound hearing loss. While these devices work well overall, results vary widely from person to person.
- Trial name
- NCT07683689
- Testing
- Everyday Clinical Listening Program (Control), ENI-Based Experimental Program 1, ENI-Based Experimental Program 2
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Cochlear Implant Users
Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints
This study examines how cochlear implant users understand and comprehend speech in realistic communication situations. Through six experiments measuring listening effort via pupillometry and discourse comprehension, we will…
- Trial name
- NCT07279441
- Testing
- Experiment 1: Syntactic and Semantic Context, Experiment 2: False Hearing and Context Overuse, Experiment 3: Two-Sentence Problem
- Where
- 2 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health