Clinical trials: Cochlear Trauma, open to volunteers
Sensorineural Hearing Loss
Hearing Preservation in Cochlear Implantation Surgery
In order to preserve the residual hearing in patients with sensorineural hearing loss (SNHL) receiving a cochlear implant (CI), the insertion trauma to the delicate and microscopic structures of the cochlea needs to be minimized.
- Trial name
- CIPRES (NCT07146841)
- Testing
- Round window insertion, Cochleostomy insertion, Lateral wall array
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- UMC Utrecht
Hearing Loss, Cochlear Trauma
SPI-1005 in Adults Receiving Cochlear Implant
The goal of this clinical trial is to learn about the effects of drug SPI-1005 in adults receiving a cochlear implant with a long electrode array (FLEX26 or greater) from MED-EL Cochlear Implant Systems into one ear.
- Trial name
- NCT06340633
- Testing
- Ebselen
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Ototoxic Hearing Loss, Ototoxicity, Drug-Induced
Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer
The goal of this observational study is to learn about the occurrence of and to identify suitable strategies for screening and monitoring of inner ear damage in patients receiving cisplatin chemoradiotherapy for head and neck…
- Conditions
- Ototoxic Hearing Loss, Ototoxicity, Drug-Induced, Cisplatin-induced Hearing Loss, Cisplatin Ototoxicity
- Trial name
- NCT06929468
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Simon Jäger
Sensorineural Hearing Loss, Tinnitus
Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing Loss
The HEAR-RESTORE study is an exploratory clinical research program designed to evaluate new diagnostic and regenerative approaches for individuals experiencing inner ear injury, tinnitus, and temporary or permanent hearing loss.
- Conditions
- Sensorineural Hearing Loss, Tinnitus, Acoustic Trauma, Inner Ear Injury
- Trial name
- HEAR-RESTORE (NCT07472023)
- Testing
- Audiologic Monitoring, Investigational Regenerative Pharmacologic Therapy, Stem Cell Regenerative Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Truway Health, Inc.
Cochlear Implants, Hearing Loss, Sensorineural
Clinical Trial to Compare Two Surgical Approaches to the Cochlea
This is a prospective multicenter multinational randomized control trial. The duration of the study for the individual patient will be approximately 1 year (pre-operative assessments, 1 week, 3 months and 12 months follow-up…
- Trial name
- BULLS-I (NCT06453343)
- Testing
- Surgical approach: cochleostomy or extended round window
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center