Clinical trials: Coeliac Disease
Celiac Disease
Gluten-free Diet Monitoring in Urine
The purpose of this study is to develope a novel method to determine gluten intake and to check gluten-free diet adherence in celiac patients by detection of gluten immunogenic peptides in urine.
- Trial name
- NCT02344758
- Testing
- Non-invasive lateral flow test for monitoring gluten intake, gluten-free diet (GFD), gluten-containing diet
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- University of Seville
Celiac Disease
A First-in-Patient Study to Evaluate the Safety and Tolerability of HB-2121 as a Diagnostic for Celiac Disease
The goal of this clinical trial is to learn about the safety of a single dose of HB-2121 in adults with suspected celiac disease. It will also look at how the drug affects the small intestine.
- Trial name
- NCT07377565
- Testing
- HB-2121
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nielsen Fernandez-Becker
Celiac Plexus Block
Endoscopic Ultrasound Guided Versus Percutaneous Celiac Plexus Block in Patients With Intractable Upper Abdominal Pain
Upper abdominal pain is a common and often debilitating symptom in patients with pancreatic cancer and chronic pancreatitis, and is frequently under-treated by standard opioid therapy despite dose escalation and associated side…
- Trial name
- NCT07865286
- Testing
- Endoscopic Ultrasound-Guided Celiac Plexus Block, Percutaneous Celiac Plexus Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Celiac Disease Patients Following Recommendations of ESPGHAN, HLA-DQ2 Typing Include HLA-DR7-DQ2 Haplotypes
Clinical Relevance of Typing HLA-DR7-DQ2
Celiac disease patients with HLA-DR7-DQ2 haplotype have the same histological, analytical and clinical behaviour as patients with HLA-DR3-DQ2 haplotype.
- Trial name
- HLA (NCT01813383)
- Testing
- There is not any intervention
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Corporacion Parc Tauli
Advanced Cancer, Pancreatic Cancer
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain
This is a prospective, single-arm, pilot feasibility clinical trial designed to evaluate the feasibility and safety of a simulation-free adaptive radiotherapy workflow to enable single-session celiac plexus SBRT planning and…
- Trial name
- Celiac SRS (NCT07636382)
- Testing
- Treatment plan
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
Patients With Coeliac Disease and Chronic Diarrhoea (>3 Loose/ Liquid Motions a Day for More Than 4 Weeks), Patients With Pancreatic Exocrine Insufficiency
Creon Use in Coeliac Patients With Low Faecal Pancreatic Elastase
Faecal elastase is an enzyme test used to identify the presence of pancreatic exocrine insufficiency. This condition manifests with symptoms of diarrhea, weight loss, causing potential impairment on an individual's quality of…
- Trial name
- NCT01865695
- Testing
- Creon
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Celiac Disease, Gluten Sensitivity
Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac Disease
This study aims to investigate how knowledge of gluten immunogenic peptide (GIP) levels in stool and urine affects subsequent adherence to a gluten-free diet.
- Conditions
- Celiac Disease, Gluten Sensitivity, Gluten Enteropathy, Gastrointestinal Disease
- Trial name
- NCT03462979
- Testing
- Immunochromatographic lateral flow test
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Pancreatic Cancer Non-resectable, Tumor Pancreas
Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic Cancer
Patients with unresectable pancreatic cancer are often demoralized by intractable, persistent and incapacitating pain. It must be managed aggressively and strong opioids are recommended as the mainstay of treatment.
- Conditions
- Pancreatic Cancer Non-resectable, Tumor Pancreas, Pain Cancer
- Trial name
- NCT06160323
- Testing
- EUS-guided coeliac ganglion neurolysis / celiac plexus neurolysis
- Where
- Hong Kong
- Volunteers
- 94 people
- Sponsor
- Chinese University of Hong Kong
Celiac Disease
Assessment of Gluten-Free Availability in Elaborated Food Stores in Three Neighbourhoods of Buenos Aires City
Celiac disease (CD) is a chronic autoimmune disorder in genetically susceptible individuals characterized by inflammation of the small intestine due to gluten intolerance.
- Trial name
- NCT02312349
- Where
- Argentina
- Volunteers
- 112 people
- Sponsor
- Hospital Italiano de Buenos Aires
Celiac Disease in Children, Nutritional Deficiency
Celiac Disease and Quality of Life in Children and Adolescents (CeliaQLife)
Celiac disease is a disorder commonly diagnosed during childhood. The treatment is a lifelong gluten-free diet. Both the condition and the diet can influence the children's physical and emotional well-being.
- Conditions
- Celiac Disease in Children, Nutritional Deficiency, Quality of Life
- Trial name
- CeliaQLife (NCT06568263)
- Where
- 2 sites in Norway
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Enteropathy, Celiac Disease
Budesonide in Patients With Immune Mediated Enteropathies
Researchers are trying to determine if withdrawal of budesonide therapy in patients with immune-mediated enteropathies doing well on therapy will result in worsening symptoms, histology, quality of life, and…
- Conditions
- Enteropathy, Celiac Disease, CVID Enteropathy, Collagenous Sprue
- Trial name
- NCT03866538
- Testing
- Withdrawal of Oral Budesonide
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Celiac Disease
Coeliac Disease in Spain: Determination of Disease Prevalence and Risk Factors
Previous studies have showed that Coeliac Disease (CD) prevalence is significantly higher in children compared with adults. The largest epidemiologic study carried out in Spain to date (n=4230) reported a higher CD prevalence in…
- Trial name
- NCT05094232
- Where
- Spain
- Volunteers
- 4,826 people, healthy volunteers welcome
- Sponsor
- Hospital Mutua de Terrassa
Celiac Disease
Effects of Gluten Digestion With ALV003
This is a Phase 0, Double-blind study that will assess the effect of in vitro treatment of gluten with ALV003 or with placebo when ingested by CD Subjects.
- Trial name
- 0801 (NCT00859391)
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Alvine Pharmaceuticals Inc.
Chronic Pancreatitis, Pancreatic Cancer
Prospective Study of Celiac Block Injection: 1 vs. 2
The purpose of this prospective randomized study is to compare the clinical effectiveness of EUS-guided CB performed with a single injection versus two injections of medication into the celiac ganglion region.
- Trial name
- NCT00583479
- Testing
- one injection into the celiac ganglion, two injections into the celiac ganglion
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Crohn's Disease, Short Bowel Syndrome
Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn's Disease Patients
Citrulline is an amino acid produced in the intestine and in the liver, but the liver does not contribute significantly to circulating citrulline concentrations.
- Conditions
- Crohn's Disease, Short Bowel Syndrome, Malabsorption Syndromes, Celiac Disease
- Trial name
- NCT00138879
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- St Mark's Hospital Foundation
Behcet Disease, Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis
Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases
Longitudinal prospective multicenter Armenian registry of systemic autoimmune, autoinflammatory diseases with constitution of bio-banking.
- Conditions
- Behcet Disease, Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis, Takayasu Arteritis, Giant Cell Arteritis
- Trial name
- NAREG (NCT05904301)
- Testing
- Usual medical management of patients, additional blood and stool samples for biobanking
- Where
- 6 sites in Armenia
- Volunteers
- 800 people
- Sponsor
- Santé Arménie French-Armenian Research Center
Celiac Disease
Tissue Destruction and Healing in Celiac Disease
The purpose of this clinical study is to learn more about celiac disease pathogenesis and clinical symptoms. In particular, this study will examine the interactions between biological factors such as, intestinal epithelial cells…
- Trial name
- NCT05680012
- Testing
- Gluten containing snack bar
- Where
- 3 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Type 1 Diabetes, Celiac Disease
Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)
The purpose of this study is to identify people with T1D or celiac disease (CD) early in the course of their disease and to improve the methods of screening for these diseases.
- Trial name
- ACCESS-T1D (NCT06908057)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Celiac Disease
Randomized, Double-Blind, Placebo-Controlled Study of Larazotide Acetate in Subjects With Active Celiac Disease
This study was conducted to assess the safety and efficacy of larazotide acetate versus placebo in inducing remission in subjects with active celiac disease.
- Trial name
- NCT00620451
- Testing
- larazotide acetate
- Where
- 33 sites in United States, Canada and 1 more
- Volunteers
- 105 people
- Sponsor
- 9 Meters Biopharma, Inc.
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong