Clinical trials: Cognition Function
Schizophrenia
The Effects of Nicotine on Cognition in Schizophrenia
Patients with schizophrenia have a variety cognitive deficits and nicotine has been shown to normalize some of these deficits. The purpose of this study is to investigate the effects of nicotine on cognition in schizophrenia.We…
- Trial name
- NCT00383747
- Testing
- transdermal nicotine patch
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Insomnia, Cognitive Impairment
RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
The goal of the study is to investigate whether treating insomnia using app-based cognitive behavioral therapy for insomnia (CBT-I) can improve cognitive impairment in breast cancer survivors compared to an active control group…
- Conditions
- Insomnia, Cognitive Impairment, Breast Cancer
- Trial name
- RESET-BRAIN (NCT06553235)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep hygiene education
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Aarhus University Hospital
Lung Diseases, Interstitial
Assessment of Neuropsychiatric Function in Patients With Interstitial Lung Disease
Research on the impact of lung diseases on neuropsychological functioning has revealed impaired cognitive processing in patients with a variety of pulmonary disorders.
- Trial name
- NCT05719233
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease COPD
Pulmonary Rehabilitation: Effects on Cognitive Functioning, Mood, Anxiety, and Quality of Life in Patients With COPD
The purpose of this project is to investigate whether a 12-week, fulltime pulmonary rehabilitation program can enhance cognitive functioning, mood, anxiety, and quality of life in patients with Chronic Obstructive Pulmonary…
- Trial name
- NCT01682447
- Testing
- Extensive Pulmonary Rehabilitation Program
- Where
- Netherlands
- Volunteers
- 261 people
- Sponsor
- Tilburg University
Cognitive Function
The Effect of Transcutaneous Vagus Nerve Stimulation on Cognitive Function
Cognitive health is generally considered a key component of quality of life. Current evidence indicates that a large number of individuals are at a high risk for cognitive impairment from many causes as they age.
- Trial name
- NCT04070547
- Testing
- Transcutaneous vagal nerve stimulation
- Where
- Czechia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Post-traumatic Stress Disorder (PTSD)
Transcranial Infrared Laser Stimulation (TILS) of Prefrontal Cognition in Post-traumatic Stress Disorder (PTSD)
This study evaluates the effects of transcranial infrared laser stimulation (TILS) on prefrontal metabolism and hemodynamics in veterans with post-traumatic stress disorder (PTSD).
- Trial name
- NCT03209882
- Testing
- TILS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas at Arlington
Cognitive Impairment, Cardiovascular Risk Factor
The Active Mind Study
The purpose of this study is to explore whether physical exercise, mindfulness training, or both interventions together can improve cognitive function in individuals with multiple risk factors for the development of dementia in…
- Trial name
- NCT03289546
- Testing
- Mindfulness training, Aerobic training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- The Miriam Hospital
Child Development, Motor Skills
Motor-Focused Exercise and Brain Development in Preschool Children
This study will test whether a structured motor-focused exercise program can improve both brain function and gross motor skills in preschool children.
- Conditions
- Child Development, Motor Skills, Neurodevelopment, Brain Function
- Trial name
- MoBraD (NCT07307742)
- Testing
- Motor-Focused Physical Education, Ordinary Physical Education
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
Bipolar Disorder
Reproductive Function in Women With Bipolar Disorder
Many studies have shown that patients with bipolar disorder are prone to reproductive dysfunction, including polycystic ovary syndrome, hyperprolactinemia, and amenorrhea.
- Trial name
- NCT05307848
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Cognition Disorders
Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults
The aim of this project is to explore whether vision correction can effectively slow cognitive decline in older adults. The primary question it seeks to answer is: Can providing free near and/or distance vision correction glasses…
- Trial name
- CLEVER (NCT06836440)
- Testing
- Free Prescription Glasses
- Where
- China
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- Yuju Wu
Effect of Sleep Deprivation
Laparoscopic Skills and Cognitive Function Are Not Affected by Night Shifts in Surgeons
The aim of the study was to asses the effect of sleep deprivation during nightshift by monitoring 30 surgeons in unit of surgical gastroenterology in 4 consecutive days.
- Trial name
- NCT01623674
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Cognitive Function 1, Social
The Effect of Cognitive Function Training Program for Community Elderly
Background. Recently, cognitive function training program has been shown to improve cognitive function in elders. However, the effects of cognitive function training program on elderly living in the community have not been…
- Trial name
- NCT05353920
- Testing
- Cognitive training
- Where
- Taiwan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Huie-Ling Chiu
Parkinson Disease, Exercise Training
SMARTfit Training for Parkinson's Disease
This pilot study aims to investigate the effects of 8-week SMARTfit training versus conventional physical training on motor function, cognition and brain functional connectivity in individuals with PD.
- Conditions
- Parkinson Disease, Exercise Training, Cognitive Change
- Trial name
- NCT03921359
- Testing
- SMARTfit training, Conventional physical training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Southern California
Cognitive Impairment, Old Age; Debility
Dietary Supplementation and Cognitive Functions in the Elderly
In recent years, globally, there has been a growth in both the size and the proportion of older adults in the world population. The World Health Organization (WHO) has estimated that by 2030, 1 in 6 people will be 60 years of age…
- Trial name
- ESPINS (NCT06352099)
- Testing
- Dietary supplement with micronised diosmin, hesperidin and herbal extracts
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Existential Suffering, Meaning of Life
Reminiscence-Based Life Review on Copying With Existential Suffering Among Older Cancer Survivors
Target Issue: Cognitive impairment in older cancer survivors is highly prevalent and the co-existing neuro-psychiatric symptoms, particularly depression, would further complicate the psychosocial consequence of existential…
- Conditions
- Existential Suffering, Meaning of Life, Cognitive Function, Psychological Distress
- Trial name
- NCT05525299
- Testing
- Reminiscence-Based Life Review
- Where
- Hong Kong
- Volunteers
- 116 people
- Sponsor
- The University of Hong Kong
Cognitive Decline, Aging
Effects of Comprehensive Community Support Programs on Cognitive Function and Quality of Life in Older Adults
This prospective observational study aims to investigate the effects of a multidomain community-based support program on cognitive function and quality of life in older adults attending the Vefahane Life Center in Istanbul…
- Conditions
- Cognitive Decline, Aging, Quality of Life
- Trial name
- NCT07610109
- Testing
- Multidomain Community Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Psychiatric Problem
Environmental Mixtures, Cognitive Control and Reward Processes, and Risk for Psychiatric Problems in Adolescence
This study aims to examine the cognitive and neural pathways underlying the joint impact of chemical and social exposures on two aspects of cognitive function: cognitive control and reward processing.
- Trial name
- NCT05795452
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Ohio State University
Alzheimer's Disease, Frontotemporal Dementia, Behavioral Variant
Non-invasive Stimulation of Brain Networks and Cognition in Alzheimer's Disease and Frontotemporal Dementia
This pilot study aims to test clinical and connectivity changes following non-invasive stimulation of disease-specific networks in Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD).
- Trial name
- NetCogBs (NCT03422250)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
PTSD, Cognitive Function
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD
Deficits in emotional cognitive control are present in a number of clinical psychiatric populations including depression, anxiety, and PTSD.
- Trial name
- SPrC-PTSD (NCT04543513)
- Testing
- Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
- Where
- United States
- Sponsor
- Laureate Institute for Brain Research, Inc.