Clinical trials: Cognitive/Functional Effects
Cognitive Impairment, Cardiovascular Risk Factor
The Active Mind Study
The purpose of this study is to explore whether physical exercise, mindfulness training, or both interventions together can improve cognitive function in individuals with multiple risk factors for the development of dementia in…
- Trial name
- NCT03289546
- Testing
- Mindfulness training, Aerobic training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- The Miriam Hospital
Effect of Sleep Deprivation
Laparoscopic Skills and Cognitive Function Are Not Affected by Night Shifts in Surgeons
The aim of the study was to asses the effect of sleep deprivation during nightshift by monitoring 30 surgeons in unit of surgical gastroenterology in 4 consecutive days.
- Trial name
- NCT01623674
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Cognitive Function 1, Social
The Effect of Cognitive Function Training Program for Community Elderly
Background. Recently, cognitive function training program has been shown to improve cognitive function in elders. However, the effects of cognitive function training program on elderly living in the community have not been…
- Trial name
- NCT05353920
- Testing
- Cognitive training
- Where
- Taiwan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Huie-Ling Chiu
Parkinson Disease, Exercise Training
SMARTfit Training for Parkinson's Disease
This pilot study aims to investigate the effects of 8-week SMARTfit training versus conventional physical training on motor function, cognition and brain functional connectivity in individuals with PD.
- Conditions
- Parkinson Disease, Exercise Training, Cognitive Change
- Trial name
- NCT03921359
- Testing
- SMARTfit training, Conventional physical training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Southern California
Schizophrenia
Effects of Cognitive Remediation Therapy on Schizophrenia Patients Through Functional Magnetic Resonance Imaging
Cognitive Remediation Therapy (CRT) can enhance cognitive performance in patients with schizophrenia improving clinical outcome. However, the neurobiological mechanism underlying cognitive improvement is not well understood.
- Trial name
- NCT01318850
- Testing
- Cognitive Remediation Therapy, Psychoeducation, Healthy controls
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Existential Suffering, Meaning of Life
Reminiscence-Based Life Review on Copying With Existential Suffering Among Older Cancer Survivors
Target Issue: Cognitive impairment in older cancer survivors is highly prevalent and the co-existing neuro-psychiatric symptoms, particularly depression, would further complicate the psychosocial consequence of existential…
- Conditions
- Existential Suffering, Meaning of Life, Cognitive Function, Psychological Distress
- Trial name
- NCT05525299
- Testing
- Reminiscence-Based Life Review
- Where
- Hong Kong
- Volunteers
- 116 people
- Sponsor
- The University of Hong Kong
Cognitive Decline, Aging
Effects of Comprehensive Community Support Programs on Cognitive Function and Quality of Life in Older Adults
This prospective observational study aims to investigate the effects of a multidomain community-based support program on cognitive function and quality of life in older adults attending the Vefahane Life Center in Istanbul…
- Conditions
- Cognitive Decline, Aging, Quality of Life
- Trial name
- NCT07610109
- Testing
- Multidomain Community Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Cognitive Symptom, Healthy
The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults
Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults. Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive…
- Trial name
- NCT04873804
- Testing
- Transcranial Direct Current Stimulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medipol University
Prediabetes, Brain Insulin Sensitivity
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals
Primary aim of the study is to assess the effect of 12-week daily avocado consumption on cerebral blood flow and markers of cardio- and vascular health in both, the periphery and the brain, in pre-diabetic individuals with…
- Conditions
- Prediabetes, Brain Insulin Sensitivity, Cerebral Blood Flow, Satiety and Food Intake
- Trial name
- NCT07752225
- Testing
- Avocados
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht University Medical Center
Chronic Pain, Opioid Use
Cognitive Function and Addiction Under Opioid Tapering
This study evaluates the effects of opioid dose reduction in the treatment of chronic pain in adults. Participants were divided in two groups: 1) patients that reduced opioid dose and 2) patients that kept the same opioid dose…
- Trial name
- NCT03365817
- Testing
- Opioids taper off, Opioid stable treatment
- Volunteers
- 75 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Schizophrenia, Cognitive and Executive Dysfunction
A Pilot Study of Adjunctive Structured Supportive Psychotherapy in Schizophrenia
This pilot randomized controlled trial examined whether adding structured supportive psychotherapy to risperidone treatment is more effective than risperidone alone in improving cognitive function and reducing peripheral…
- Conditions
- Schizophrenia, Cognitive and Executive Dysfunction, Neuroinflammation
- Trial name
- PILOT-SSP-SCZ (NCT07671040)
- Testing
- Structured supportive psychotherapy, Risperidone, Unstructured Supportive Conversation
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Hasanuddin University
Alzheimer's Disease
Effects of Triglycerides on Age-Related Cognitive Function Decline in Older Subjects
This is a single centre, 2 part study in older subjects. Part 1 (Pharmacokinetic [PK] Assessment) is a double blind, randomized, placebo-controlled 4-period crossover study investigating the PK profile of four different doses of…
- Trial name
- NCT01702480
- Testing
- GSK2981710
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- GlaxoSmithKline
Health and Wellbeing
A Single Group Study to Evaluate the Effects of a Multivitamin on a Range of Health and Wellbeing Outcomes.
This is a hybrid single-group clinical trial that will last 12 weeks. Participants will take 2 capsules daily with the first meal of the day in the morning. Participants will undertake blood tests at Baseline and Week 12.
- Trial name
- NCT06568146
- Testing
- Multivitamin Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Mild Cognitive Impairment, NAD
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
The purpose of this study is to determine the effects of Niagen (nicotinamide riboside, vitamin B3), on NAD levels, brain function including cognition and blood flow in people diagnosed with mild cognitive impairment (MCI).
- Trial name
- NAD (NCT02942888)
- Testing
- Nicotinamide riboside, Sugar Pill
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Effect of Superstarch on Soccer Performance
Superstarch and Physical/Cognitive Performance Following a Simulated Soccer Game
To assess the efficacy of a hydrothermally modified starch supplement (Superstarch made byGeneration UCAN) vs isoenergetic placebo (glucose) on exercise performance, execution of specific soccer skills, and on cognitive function…
- Trial name
- NCT02667340
- Testing
- Superstarch
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Stroke
Effect of Pilates Training on Cognitive Functions in Patients With Stroke
The purpose of the present study is to investigate the effect of pilates training on cognitive functions in patient with stroke
- Trial name
- NCT04157582
- Testing
- Pilates training, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Pulmonary Hypertension
Acute Exposure of High Altitude on Cognitive Function
Randomized crossover Trial in patients with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary Hypertension (CTEPH) to assess the acute response to High Altitude (2500m above sea level) on cognitive…
- Trial name
- NCT03637192
- Testing
- Low altitude: 470m above sea level, Säntis; 2500m above sea Level
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Behavior Problems, Attention Problems
Effect of Sports Based Structured Cognitive Therapy Program on Attention, Memory and Behavior for School Going Children
This randomized controlled trial will evaluate the effect of a sports-based structured cognitive therapy program on attention, memory, and behavior in school-going children aged 8-12 years with mild to moderate attention or…
- Conditions
- Behavior Problems, Attention Problems, Cognitive Functions
- Trial name
- NCT07786532
- Testing
- Sports-Based Structured Cognitive Therapy Program, Conventional Physical Activity
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Age-Related Memory Disorders
A Study to Evaluate The Effects Of a Multivitamin/Mineral With Ginko In Subjects With Age Associated Memory Impairment
A Study to evaluate the cognitive effects and tolerance of a Multi-Vitamin/Mineral Preperation containing Gingko in elderly subjects with age associated memory impairment.
- Trial name
- NCT01160692
- Testing
- Multivitamin/Multimineral/Ginkgo (BAY 81-2775)
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Bayer
Sedentary Behaviors, Physical Inactivity
Effects of Virtual Reality and Traditional Exercise on Cognitive and Physical Performance in Sedentary Adults
This study aimed to compare the effects of virtual reality (VR)-based exercise and traditional exercise methods on selected physiological and cognitive parameters in sedentary individuals.
- Trial name
- VR-TRAD-EX (NCT07567144)
- Testing
- Virtual Reality Exercise Training, Traditional Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University