Clinical trials: Cognitive
Dementia, Aerobic Exercise
Investigation of the Effects of Aerobic Exercise, Balance Exercise and Combined Exercise Practices on Frailty, Balance, Fall Risk, Reaction Time, Cognitive Functions and Quality of Life in Dementia Patients
Dementia is a clinical disorder characterized by progressive and permanent loss of multiple cognitive functions, especially memory, at a level that affects activities of daily living.
- Conditions
- Dementia, Aerobic Exercise, Balance Exercise, Cognitive Function
- Trial name
- NCT05839743
- Testing
- Aerobic Exercise, Balance Exercise, Combined Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Yuksek Ihtisas University
Alzheimer Disease, Mild Cognitive Impairment
Gamma Induction for Alzheimer's Disease
Alzheimer's Disease (AD) is characterized by amyloid-β (Aβ) plaque buildup and phosphorylated tau (p-tau) in the brain, as well as widespread neurodegeneration.
- Trial name
- NCT03880240
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Hepatitis C, Cognitive Impairment
P300 in Early Cognitive Impairment in Hepatitis C Virus
Approximately 50% of patients with hepatitis C have complaints of fatigue and cognitive deficits even before the development of significant hepatic impairment.
- Trial name
- NCT04389268
- Testing
- Visual Event-Related Potentials
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Delirium, Cognitive Dysfunction
Biomarkers in Cerebrospinal Fluid in Critical Care Patients With Delirium
Critical care patients are at a high risk of developing delirium and impaired cognitive function 3 and 12 months after their ICU stay.
- Trial name
- BIO-ICU (NCT02948374)
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Sahlgrenska University Hospital
Rheumatoid Arthritis, Cardiovascular Diseases
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk…
- Conditions
- Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
- Trial name
- CARE RA (NCT04488497)
- Testing
- Cardiovascular Risk Assessment for Patients with Rheumatoid Arthritis, Standard of care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cognitive Benefits
Citicoline, Creatine, and Omega-3 Effects in Middle Age Women
The purpose of this study is to determine the functional effects of a citicoline, creatine, and omega-3 fatty acids combination when administered for a duration of four weeks (28 days) to non-psychiatric adult female participants.
- Trial name
- NCT01502813
- Testing
- Citicoline, Omega-3 Fatty Acids and Creatine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Deborah Yurgelun-Todd
Adolescent Idiopathic Scoliosis
The Effect of Conservative Treatment on Perceptual and Cognitive Asymmetry in Scoliosis
Adolescent idiopathic scoliosis (AIS) patients have been found to exhibit cortical asymmetry. This study aimed to examine the impact of conservative treatments on perceptual and cognitive asymmetry in the auditory system assessed…
- Trial name
- NCT06141759
- Testing
- Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Exercise, Aerobic Exercise
Acute Effects of Trampoline Exercises
The aim of the study is to investigate the acute effects of trampoline exercises on balance, proprioception, vertical jump and cognitive functions.
- Trial name
- NCT05345535
- Testing
- Trampoline exercise, Walking
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Schizophrenia; Psychosis, Nurse's Role
Effect of Applying Cognitive Defusion Techniques on Mindful Awareness, Cognitive Fusion and Believability of Delusions Among Clients With Schizophrenia
Schizophrenia causes hallucinations, delusions, and disorganized thinking, resulting in decreased functioning and lifelong therapy.Delusion believability is the degree of belief in the truth of one's subjective experiences as…
- Conditions
- Schizophrenia; Psychosis, Nurse's Role, Delusions
- Trial name
- NCT05759091
- Testing
- cognitive defusion techniques
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Alexandria University
Frontal Lobe Dementia, Frontotemporal Lobe Dementia
Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal Dementia
The primary objective of the study is to determine whether memantine is effective in slowing the rate of behavioral decline in frontotemporal dementia.
- Conditions
- Frontal Lobe Dementia, Frontotemporal Lobe Dementia, Semantic Dementia
- Trial name
- NCT00545974
- Testing
- memantine
- Where
- 9 sites in United States
- Volunteers
- 81 people
- Sponsor
- University of California, San Francisco
Schizophrenia, Neuroimaging
The Difference of Grey Matter Volume Among the Patients of Schizophrenia
Schizophrenia is a heritable complex phenotype whose symptoms can be clustered into three domains: positive symptoms, negative symptoms and cognitive impairments.
- Conditions
- Schizophrenia, Neuroimaging, Cognitive Dysfunction
- Trial name
- NCT05262790
- Testing
- This is not an intervention study
- Volunteers
- 253 people
- Sponsor
- Shanghai Mental Health Center
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Pain
HELP Pain Training Program
The aim of this project is to develop and test the Helping Educators Learn Pediatric Pain Assessment \& Intervention Needs (HELP Pain) program.
- Trial name
- NCT05698290
- Testing
- HELP Pain Training Program
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Michigan State University
Fronto-temporal Dementia, Fronto-temporal Lobar Dementia
Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
The goal of this clinical trial is to learn if vortioxetine improves mood symptoms and cognition in patients with early-stage behavioral variant Frontotemporal Dementia (bvFTD).
- Conditions
- Fronto-temporal Dementia, Fronto-temporal Lobar Dementia, Frontotemporal Degeneration, Frontotemporal Dementia (FTD)
- Trial name
- NCT06604520
- Testing
- Vortioxetine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Maternal Exposure, Health Behavior
Brain Probiotic and LC-PUFA Intervention for Optimum Early Life
Probiotics is suggested to play several roles in promoting health, including alleviating disease symptoms, protection against atopic disease, and modulating the immune system by improving the beneficial gut microbiota…
- Conditions
- Maternal Exposure, Health Behavior, Infant Development, Child Development
- Trial name
- BRAVE (NCT03851120)
- Testing
- Probiotics and LC-PUFA (480 mg DHA), Psychosocial stimulation and healthy eating education
- Where
- Indonesia
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Chronic Pain, Opiate Dependence
Cognitive-Behavioral Therapy for Pain and Opioid Dependence in Methadone Maintenance Treatment
This study involves the comparison of two treatment approaches for patients with chronic pain who are entering methadone maintenance treatment (MMT) for opioid addiction: (a) an integrated counseling that addresses both chronic…
- Trial name
- NCT01334580
- Testing
- Cognitive-Behavioral Therapy for Pain and Opioid Dependence, Methadone Drug Counseling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Mild Cognitive Impairment, Alzheimer Disease
White Matter Hyperintensities in Amnestic Mild Cognitive Impairment or Alzheimer's Disease
This study focuses on assessing and measuring white matter hyperintensities in individuals with amnestic mild cognitive impairment (aMCI) or Alzheimer's disease.
- Trial name
- NCT06179680
- Testing
- Magnetic Resonance Imaging
- Where
- Italy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Traumatic Brain Injury, Post-Concussive Symptoms
Long-Term Outcomes Following HBOT
This study is designed to better understand the long-term effects of hyperbaric oxygen therapy (HBOT). Our goal is to determine whether improvements after treatment are maintained over time and whether additional benefits appear…
- Conditions
- Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
- Trial name
- NCT07732374
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Summit Hyperbarics and Wellness
Depression
Trial of Telephone-based Psychotherapy for Depression With and Without Adjunctive Supportive Mail
This study aims to compare the effectiveness of two telephone-based psychotherapy (Tel-PT) interventions for patients with mild to moderate depression.
- Trial name
- Tel-PT (NCT01770990)
- Testing
- Tel-PT including mail, Tel-PT without mail
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Sensory Impairments, Cognitive Impairment
Development of an Ensemble Learning-based, Multi-dimensional Sensory Impairment Score to Predict Cognitive Impairment in an Elderly Cohort of Southern Italy
There is now strong scientific literature showing a relationship between sensory loss and cognitive performance and between sensory loss and incident dementia.
- Conditions
- Sensory Impairments, Cognitive Impairment, Artificial Intelligence
- Trial name
- DEMETRA (NCT06783010)
- Volunteers
- 30 people
- Sponsor
- Azienda Sanitaria Locale Bari