Clinical trials: Cognitive Change
Antipsychotics, Cognition
Change in Brain Metabolism and Cognitive Function by Aripiprazole
Dopamine receptor occupancy and brain metabolism were measured using positron emission tomography after the administration of aripiprazole. Working memory performance was also measured using N-back task.
- Conditions
- Antipsychotics, Cognition, Brain Metabolism, Dopamine Receptor Occupancy
- Trial name
- NCT01562808
- Testing
- Aripiprazole
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Nutrition, Cognitive Change
Effect of Morning Snack on Cognitive Performance in Adults
To characterize the effects of three chocolate snacks on cognitive performance, subjective appetite, food intake control, and glycemic response in normal weight adults.
- Conditions
- Nutrition, Cognitive Change, Food Intake Control, Satiety
- Trial name
- NCT03637829
- Testing
- Control, White chocolate, Dark chocolate 1
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Cognitive Change, Musculoskeletal Pain
Osteopathic Manipulation Makes a Neuropsychological Difference
Patients with pain commonly experience cognitive impairment. While symptoms of pain are effectively treated with osteopathic manipulative treatment (OMT), the cognitive piece is vastly ignored.
- Trial name
- BOD (NCT04058431)
- Testing
- Osteopathic Manipulative Treatment, Control- No Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Midwestern University
Cognitive Change
Mindfulness Training for Senior Leaders
The overarching goal of the project is to investigate if a mindfulness-based attention training (MBAT) program contextualized for Military Senior Leaders (SLs) might benefit SLs in three key domains: (1) cognitive abilities, (2)…
- Trial name
- NCT04576832
- Testing
- Mindfulness-Based Attention Training (MBAT) web-course
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dehydration, Weight Loss
Effect of Dehydration on Sleep Quality, Cognitive Skills, and Electromyographic Responses in Combat Athletes
This study examines the effects of rapid dehydration-induced weight loss on combat athletes' sleep quality, cognitive skills, and isokinetic strength performance.
- Conditions
- Dehydration, Weight Loss, Weight Cycling, Sleep
- Trial name
- NCT07118904
- Testing
- Rapid weight loss through dehydration
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Dementia, Cognitive Change
MIND Diet to Improve Cognitive Function in Mild Stroke Patients
A 6-month pilot randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet + usual medical care versus usual medical care on the rate of cognitive change…
- Conditions
- Dementia, Cognitive Change, Stroke, Cerebral Infarction
- Trial name
- MINDICOMS (NCT05921084)
- Testing
- MIND diet intervention, General dietary advice
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhejiang University
Meningioma
Evaluation of Brain Functional Changes With 18F-FDG PET and Cognitive Processes After Brain Radiotherapy for Cavernous Sinus Meningiomas and Non-secreting ACTH Adenomas
The use of radiotherapy for irradiation of all or part of the brain, in the treatment of extracerebral intracranial neoplasms, is growing rapidly, both due to the increase in diagnoses of primary tumors thanks to new imaging…
- Trial name
- NCT06180226
- Testing
- PET CT with 18 FDG .
- Volunteers
- 20 people
- Sponsor
- IRCCS San Raffaele
Chronic Kidney Diseases, Obesity
Cognitive-Behavioral Therapy for Managing Obesity in People With Chronic Kidney Disease
In the study Cognitive-Behavioral Therapy (CBT) for Managing Obesity in People with Chronic Kidney Disease (CKD) the investigators will test whether CBT programme is effective for weight loss and weight maintenance after the…
- Conditions
- Chronic Kidney Diseases, Obesity, Overweight
- Trial name
- NCT05927337
- Testing
- Cognitive Behavioral Therapy (CBT) for managing Obesity
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Schizophrenia
Roflumilast Plus Antipsychotics Proof of Mechanism Study in Schizophrenia
The purpose of this study is to determine whether cognitive impairment associated with schizophrenia is attenuated by add-on roflumilast administration to second generation antipsychotics (SGA) in participants with stable…
- Trial name
- NCT02079844
- Testing
- Roflumilast, Second generation antipsychotic
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Takeda
Clinical High Risk for Psychosis (CHR)
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
The goal of this clinical trial is to learn how tests undertaken by people at high risk of developing psychosis (aged 17 to 30 years old) change when those people are given the study drug MT1988 daily for 8 weeks.
- Trial name
- NCT07226895
- Testing
- MT1988 Low Dose, MT1988 High Dose
- Where
- 15 sites in United States
- Volunteers
- 150 people
- Sponsor
- Monument Therapeutics Limited
Healthy Volunteers
Longitudinal Development of Behavior and Its Underlying Neural Correlates in Human Infants
The unique importance of human brain development during the first years of life is unquestionable. During an infant's first year, the brain undergoes its most dramatic structural and functional changes, with factors such as early…
- Trial name
- MultiLongDev (NCT05167565)
- Testing
- MRI/DTI, EEG, Eye Tracking
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Alzheimer, Cognitive Unimpaired
Brain Heath Service for Prevention of AD
The aim of the program to serve as a prototype for future preventive program for AD in the region. The program will recruit elderly participants.
- Conditions
- Alzheimer, Cognitive Unimpaired, Mild Cognitive Impairment
- Trial name
- BEAT AD (NCT07834528)
- Testing
- medical referral and/or educational programs
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Physical Inactivity, Aging
Motivating Activity Through Text Communications - Helping Adults Increase Movement
The goal of this clinical trial is to compare the effect of different types of text messages on physical activity levels of middle-aged and older adults and to determine whether these messages are effective in adults age 40 and…
- Conditions
- Physical Inactivity, Aging, Cognitive Ability, Behavior Change
- Trial name
- MATCH AIM (NCT07593677)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Multiple Sclerosis, Cognitive Dysfunction
HOBSCOTCH-MS-Efficacy Trial
The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-MS to improve the quality of life and cognitive function in Service Members, Veterans and civilians who have multiple sclerosis with…
- Conditions
- Multiple Sclerosis, Cognitive Dysfunction, Memory Disorders, Memory Impairment
- Trial name
- NCT06951919
- Testing
- Home Based Self- management and Cognitive Training Changes lives in Multiple Sclerosis (HOBSCOTCH-MS)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Depression
Brief Culturally Adapted Cognitive Behaviour Therapy for Depression
Cognitive behaviour therapy (CBT) has an effective evidence base in the west and is recommended by the national bodies in many countries in the West.
- Trial name
- NCT01799551
- Testing
- Ca CBT
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Depression, Anxiety
Improving Psychological Wellness After Acquired Brain Injury
The purpose of the study is to investigate the potential benefits of a psychological therapy, called cognitive behaviour therapy (CBT), for improving emotional well being after acquired brain injury and to demonstrate its…
- Conditions
- Depression, Anxiety, Brain Injury
- Trial name
- NCT00866632
- Testing
- Cognitive Behavioural Therapy
- Where
- 2 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Toronto Rehabilitation Institute
Hypochondriasis, Somatoform Disorders
Comparing Cognitive Therapy and Exposure Therapy in Individuals With Hypochondriasis
This study will compare the efficacy of cognitive therapy and exposure therapy for treating hypochondriasis.
- Trial name
- NCT01119469
- Testing
- Psychotherapy (CT or ET)
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- Goethe University
Cognitive Change
Effect of Arshvidya After School Program on Cognitive Processes in Elementary School Children
The impact of Arsha Vidya program on cognitive performance was examined in elementary school children. The study compares the effects of arsha vidya after school routine with usual after school routine in healthy 8-11 year-old…
- Trial name
- NCT03813888
- Testing
- Arsha Vidya chldren's Group, Usual Activity group
- Where
- India
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Obesity, Cognitive Change
Effects of Weight Loss Management on Cognitive Function in Elderly Women With Obesity
According to studies, the risk of cerebrovascular disease and cognitive decline are associated with age-related changes. In addition, there is data suggesting a relationship between the progression of this pathology and the…
- Trial name
- NCT05841173
- Testing
- "PanTrek", Physical Trainings, Diet
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Federal State Budgetary Scientific Institution
Sedentary Behavior, Cardiovascular Risk Factor
Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System
Prolonged sitting may pose a public health risk through its effects on the cardiovascular system, and may lead to impaired whole-body cardiovascular health, which includes both vascular and cerebrovascular function.
- Conditions
- Sedentary Behavior, Cardiovascular Risk Factor, Mental Stress, Cognitive Change
- Trial name
- NCT04207333
- Testing
- Mental Arithmetic Test
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill