Clinical trials: Cognitive Changes
Diabetes Mellitus, Type 2, Insomnia
A Study Looking to Improve Sleep and Reduce Sedentary Behaviour in Those Living With Type 2 Diabetes Mellitus
The goal of this clinical feasibility trial is to learn whether the investigators can improve sleep and reduce sedentary behaviour in people living with Type 2 diabetes mellitus with sleep problems.
- Conditions
- Diabetes Mellitus, Type 2, Insomnia, Sedentary Behavior
- Trial name
- NCT06471634
- Testing
- CBTi, Control - usual care, Sedentary behaviour reduction
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- University of Leicester
Cognitive Change
Cerebral Excitability and Cognitive Performance
This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.
- Trial name
- NCT03807934
- Testing
- Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tufts University
Obesity, Morbid
Pre- and Postoperative Cognitive Behavior Therapy for Patients Accepted for Bariatric Surgery
The purpose of this study is to investigate the relationship between the potential predictive psychological variables and success after bariatric surgery.
- Trial name
- NCT00635011
- Testing
- psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Helse Fonna
Obesity
Adapted Cognitive Behavioral Approach to Addressing Overweight and Obesity Among Qatari Youth
Levels of overweight and obesity have reached alarming proportions in Qatar and other Gulf nations. In Qatar, the need to establish national strategies for the prevention and treatment of obesity has been recognized in the new…
- Trial name
- NCT02972164
- Testing
- Weight loss program for school children
- Where
- Qatar
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- Qatar University
Chronic Psychosis
Behavioral and Cognitive Therapies for Auditory Hallucination Management
The present study wants to evaluate the efficacy of a short psychoeducational type group intervention and Cognitive behavioral therapy (CBT) 3rd wave on the severity of hallucinatory Acoustico-Verbal (HAV) symptomatology in…
- Trial name
- AcceptVoice (NCT03348787)
- Testing
- Behavioral and Cognitive Therapies
- Where
- 5 sites in France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Toulouse
Psychological Stress, Anxiety
Mindfulness Training in U.S. Army Cohorts
This project aims to contextualize delivery of mindfulness training to U.S. Army personnel, evaluate its effectiveness on measures of executive functions and psychological well-being, and determine best practices for its delivery.
- Conditions
- Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT03310112
- Testing
- 4-week MBAT, 2-week MBAT
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Parkinson's Disease, Mild Cognitive Impairment
Effect of Transcranial Magnetic Stimulation on Cognition and Neural Changes in Parkinson's Disease
Parkinson's disease (PD) affects more than 100,000 Canadians and results in symptoms affecting both motor and cognitive (thinking and memory) functions.
- Trial name
- PD-MCI-TMS (NCT03243214)
- Testing
- TMS
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of Calgary
Postoperative Cognitive Dysfunction
Correlations of Epigenetic Changes With POCD in Surgical Patients
Postoperative cognitive dysfunction (POCD) is a subtle cognitive dysfunction, especially postoperative memory impairment lasting for weeks or months. The underlying pathophysiological mechanism of POCD remain unclear.
- Trial name
- NCT02965235
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Central South University
Insomnia Disorder, Cognitive Functioning
Assessing Modified CBTi in Adults With Insomnia Disorder
Cognitive Behavioral Therapy for Insomnia (CBTi) is the gold-standard, first line recommended treatment for insomnia, and has considerably better long-term outcomes than medications.
- Trial name
- NCT06600516
- Testing
- CBTi: Stimulus Control Core, CBTi: Sleep Restriction Core, CBTi: Sleep Compression Core
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Idaho State University
Mood, Cognitive Change
OxPALM: Oxford Study on Probiotics and Low Mood
Probiotics are live bacteria which have been suggested to have beneficial effects not only on gut function but also on psychological and cognitive functioning.
- Trial name
- NCT03801655
- Testing
- Bio-Kult
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Schizophrenia
The Effects of Prebiotics on Cognitive Functioning and Weight Gain in Psychosis
The investigators propose a maltodextrin-controlled cross over experimental medicine study that aims to examine the role of the immune system in cognitive processes and weight gain in 40 adult patients with psychosis, stable on…
- Trial name
- Prepsy (NCT03153046)
- Testing
- prebiotics, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- University of Oxford
Cognitive Impairment
Changes in Cognition During a 24-h Simulated Military Operation
Sustained military operations (SUSOPs) result in psychological stress and cognitive dysfunction, which may be related to the recruitment of classical monocytes into the brain.
- Trial name
- NCT04250480
- Testing
- beta-alanine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Neurologic Disorder, Brain Injuries
Effect of Transcranial Direct Current Stimulation in Altered States of Consciousness
Transcranial Direct Current Stimulation (tDCS) is a non-invasive, painless brain stimulation treatment that uses low-intensity direct electrical currents to stimulate specific parts of the brain.
- Trial name
- tDCS-GCA (NCT06236503)
- Testing
- Real Stimulation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Amnestic Mild Cognitive Disorder, Amnestic Mild Cognitive Impairment
Modified Ketogenic Diet in Amnestic Mild Cognitive Impairments
This clinical study aims to examine the effectiveness of a 12-week modified ketogenic diet (MKD) intervention, especially on cognitive functions, in individuals diagnosed with amnestic-mild cognitive impairment (aMCI) and to…
- Trial name
- NCT06444568
- Testing
- Dietary Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Chemotherapy-related Cognitive Impairment
Evaluating Cognitive Changes on Patients in Chemotherapy (ECCPC)
This randomized clinical trial aims to evaluate the impact of a structured low-intensity exercise program on cognitive function in adult cancer patients undergoing chemotherapy.
- Trial name
- (ECCPC) (NCT06950190)
- Testing
- Low-Intensity Walking Intervention, Control Group Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ellis Medicine
Cognitive Change, Mood
Effect of PeakATP on Mood, Reaction Time and Cognition
Oral ATP disodium (adenosine 5'- triphosphate disodium) is a commercially available product available alone and as a constituent in a number of sports supplements that is purported to maintain ATP levels and improve performance…
- Trial name
- NCT05100589
- Testing
- PeakATP
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Cognitive Change
Effect of a Fermented Dairy Food With Probiotics on Mental Performance
Single-center, randomized, double-blind, placebo-controlled clinical study with two study groups. One group will consume a product with functional ingredients and the other group will consume a placebo product.
- Trial name
- ShotRM (NCT05323825)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Spinal Cord Injuries, Neuropathic Pain
Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury
Many adults with spinal cord injury (SCI) suffer from long-term debilitating neuropathic pain. Available treatments, including opioids, are ineffective at eliminating this pain.
- Trial name
- NCT04706208
- Testing
- Cognitive Multisensory Therapy, Usual Care, Clinical Assessment
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression, Unipolar, Depressive Disorder
Gaze Contingent Feedback in Major Depressive Disorder (MDD)
The purpose of this study is to determine whether giving gaze-contingent feedback is an effective attention modification procedure, helping in the treatment of Major Depressive Disorder (MDD)
- Conditions
- Depression, Unipolar, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02945735
- Testing
- Attention Modification
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University