Clinical trials: Cognitive Disability
Schizophrenia / Schizoaffective Disorder
A Cognitive Mobile Intervention for Motivation in Psychotic Disorders
The goal of this study is to develop and test the impact of a smartphone-based working memory cognitive training digital therapeutic for individuals with schizophrenia or a related disorder.
- Trial name
- NCT07674914
- Testing
- Cognitive Training, Mobile cognitive training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Alabama at Birmingham
Obstructive Sleep Apnea
Effect of CPAP Treatment in Cognition in Adults With DS and OSA
Adults with Down syndrome (DS) have a high prevalence of obstructive sleep apnea (OSA), which may worsen cognitive performance. In general population, continuous positive airway pressure (CPAP), the gold Standard treatment for…
- Trial name
- NCT04198493
- Testing
- CPAP, CONSERVATIVE TREATMENT for OSA
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Intellectual Disability
Evaluation of the Effect of Digital-based Games on the Visual and Cognitive Performance of Young Children With Intellectual Disabilities
This randomized controlled trial aims to evaluate the effect of digital intelligence games on visual and cognitive performance in young individuals with intellectual disabilities.
- Trial name
- NCT07476092
- Testing
- MentalUP Digital Intelligence Game
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Koç University
Intellectual Disabilities
Picture-based Computerised Assessment and Training of Cognitive Behaviour Therapy Skills
The proposed research aims to investigate whether people with intellectual disabilities are able to understand and apply the theoretical principles of cognitive behaviour therapy (CBT) regarding the interaction between events…
- Trial name
- NCT01652963
- Testing
- Reed and Clements Training Task
- Where
- 3 sites in United Kingdom
- Volunteers
- 132 people
- Sponsor
- University of East Anglia
Functional Disability, Dynapenia
Multicomponent Training on Functional and Cognitive Performance of Hospitalized Older People
The goal of this clinical trial is to determine whether a multicomponent physical exercise program improves functional and cognitive capacity in hospitalized older adults compared to the usual hospital care.
- Conditions
- Functional Disability, Dynapenia, Cognitive Decline
- Trial name
- NCT06682598
- Testing
- Multicomponent physical exercise training
- Where
- Brazil
- Volunteers
- 47 people
- Sponsor
- Federal University of Rio Grande do Sul
Math Learning Disability
Understanding Cognitive-Academic Bidirectionality in Math Learning Disabilities
The goal of this clinical trial is to test the effects of an innovative intervention designed to improve math skills in first graders at risk for math disabilities.
- Trial name
- NCT07220746
- Testing
- Coordinated Treatment, Math Treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Vanderbilt University
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Multiple Sclerosis, Relapsing-Remitting
Cognitive Disability and Quality of Life of Patients Suffering From Multiple Sclerosis and Treatment With Immunosuppressant
Multiple Sclerosis is the first cause of neurological handicap in France. The importance of cognitive disabilities, their evaluation and their impact on patients' life have only been comprehended recently.
- Trial name
- CoQualSEP (NCT01392872)
- Testing
- Neuropsychological assessment
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Chronic, Dementia, Mild
Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia
The purpose of this study is to develop an exercise treatment program for knee osteoarthritis that works well for people with memory problems. This study will include two parts.
- Conditions
- Pain, Chronic, Dementia, Mild, Mobility Limitation, Physical Disability
- Trial name
- NCT06264362
- Testing
- Tailored Physical Activity Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Drexel University
Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication
Red Blood Cell Transfusion in ECMO - A Feasibility Trial
Extracorporeal Membrane Oxygenation (ECMO) is an invasive and resource intense treatment used to support critically ill patients who have suffered severe cardiac arrest, cardiac failure or respiratory failure (including severe…
- Conditions
- Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication, Disability Physical, Cognitive Ability, General
- Trial name
- ROSETTA (NCT05814094)
- Testing
- Red Blood Cell Transfusion
- Where
- 2 sites in Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Fatigue
Sleep and Training Aspects in Dialysis Fatigue - Exercise Intervention
The purpose of the current study is to investigate whether changes in patients' sleep quality and quantity will be followed by improvements in parameters related to physical and mental fatigue in patients receiving hemodialysis…
- Trial name
- StandFirm (NCT01721551)
- Testing
- Exercise, Usual Treatment
- Where
- 3 sites in Greece
- Volunteers
- 50 people
- Sponsor
- University of Thessaly
Fragile X Syndrome, FXS
A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome
This is a single-center, randomized, double-blind, 2-period crossover study to explore the effects of BPN14770 on cognitive function and behavior in subjects with Fragile X Syndrome.
- Conditions
- Fragile X Syndrome, FXS, Fra(X) Syndrome
- Trial name
- NCT03569631
- Testing
- BPN14770
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tetra Discovery Partners
Intellectual Disability
Therapy-Based Games' Effects on Motor and Cognitive Skills in Intellectual Disabilities
Individuals with intellectual disabilities face challenges in areas of attention, motor skills, and awareness. Among the problems they experience are difficulties in focusing, transitioning from one activity to another…
- Trial name
- NCT06097819
- Testing
- Mobile app-based game group, Supervised combined sensor-based game group, Individualized occupational therapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Medipol University Hospital
Chronic Nonspecific Low Back Pain
Dual-Task Core Stabilization Training in Chronic Nonspecific Low Back Pain
This study will investigate whether adding cognitive tasks to core stabilization exercises improves the ability to perform physical and mental tasks simultaneously in adults with chronic nonspecific low back pain.
- Trial name
- DT-CSE (NCT07894965)
- Testing
- Dual-Task Core Stabilization Exercise, Single-Task Core Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karabuk University
Dyslexia, Executive Dysfunction
The Effects of Play and Competition-Based Cognitive Therapy
Purpose: The aim of this study was to investigate the effects of play and competition-based cognitive therapy (PCB-CT) on executive function and occupational routines in children with dyslexia.
- Trial name
- NCT03906097
- Testing
- Play and Competition-Based Cognitive Therapy
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
Development Delay, Child Development
Psychological Correlates of Developmental Delays in Preschool Children
The goal of this observational study is to investigate perinatal, cognitive, linguistic and social-emotional correlates of developmental delays of preschool children.
- Conditions
- Development Delay, Child Development, Social Functioning, Speech Delay
- Trial name
- NCT07420829
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Fragile X Syndrome
"Using Epigallocatechin Gallate (EGCG) and Cognitive Training to Modulate Cognitive Performance in Patients With Fragile X Syndrome" (TESFX)
Fragile X syndrome (FXS) presents alterations in synaptic plasticity that produce intellectual disability. can produce improvement.
- Trial name
- NCT01855971
- Testing
- EGCG, Cognitive training
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Parc de Salut Mar
Depressive Symptoms
Group Therapy Program for Women With Physical Disabilities
More women with disabilities (30%) report "feelings such as sadness, unhappiness, or depression that prevent them from being active" compared to women without disabilities (8%).
- Trial name
- CBT-WPD (NCT00618566)
- Testing
- WPD and Depression Treatment Group
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Oregon Health and Science University
Fragile X Syndrome
Study of SPG601 in Adult Men With Fragile X Syndrome
This Phase 2 study described herein will evaluate the safety, efficacy, tolerability, pharmacokinetics and pharmacodynamics of SPG601 in adult men with Fragile X syndrome.
- Trial name
- NCT06413537
- Testing
- SPG601
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Spinogenix