Clinical trials: Cognitive Disability
Depression, Anxiety
BEhavioral Health Stratified Treatment (BEST) Study for Youth With Intellectual and/or Developmental Disabilities (IDD)
Many youth with disabilities and their families receive "care coordination services" from a state Maternal and Child Health Bureau (MCHB) agency.
- Conditions
- Depression, Anxiety, Transition
- Trial name
- BEST (NCT05520983)
- Testing
- Adapted Teens Achieving Mastery over Stress (TEAMS) Treatment, Adapted Teens Achieving Mastery over Stress (TEAMS) Prevention, Adapted Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT)
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Intellectual Disabilities
Examine the Effects of 24-week Exercise Program on Functional Capacity, Cognitive Capacity, and Quality of Life in Individuals With Intellectual and Developmental Disabilities
Physical inactivity and a sedentary lifestyle are prevalent in the population with intellectual and developmental disabilities, and they do not comply with the World Health Organisation's physical activity guidelines.
- Trial name
- NCT06180304
- Testing
- Exercise training
- Where
- Portugal
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Leiria
Suicide, Suicide, Attempted
Brief Cognitive Behavioral Therapy for People With Physical Disabilities
The purpose of this study is to examine the effectiveness of a psychotherapy (non-medication) treatment, Brief Cognitive Behavioral Therapy for Suicide Prevention, in reducing suicide ideation and attempts for people with…
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Disability Physical
- Trial name
- NCT05695430
- Testing
- Brief Cognitive Behavioral Therapy for People with Physical Disabilities
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ohio State University
Hearing Disability, Depression
Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching
The purpose of this study is to see if a mobile-delivered mental health program called Toivoa-002, which combines digital cognitive behavioral therapy (CBT) with personal coaching, can effectively reduce depression in adults with…
- Conditions
- Hearing Disability, Depression, Mobility Disability
- Trial name
- NCT07195292
- Testing
- Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Toivoa Inc
Mild Intellectual Disability, Borderline Intellectual Functioning
Improving the Cognitive Accessibility of Self-reports for People With ID
In the proposed study, the investigators aim to investigate whether the existing ABAS-3 self-report questionnaire is suitable to be completed meaningfully by individuals who are perceived as having mild intellectual disability…
- Trial name
- NCT05857592
- Testing
- Adaptive functioning self-report questionnaire, Adaptive functioning self-report questionnaire - adapted
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Koraal
Velocardiofacial Syndrome, Williams Syndrome
The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome
The purpose of this study is to investigate the Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome (VCFS), Williams Syndrome (WS)and Fragile X Syndrome Characterization, Treatment and Examining the Connection to…
- Conditions
- Velocardiofacial Syndrome, Williams Syndrome, Fragile X Syndrome
- Trial name
- VCFS (NCT00768820)
- Testing
- methylphenidate, fluoxetin, risperidone
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- The Chaim Sheba Medical Center
Low Back Pain, Non Specific Chronic Low Back Pain
Comparative Effects of Cognitive Functional Therapy With Kinetic Control Training on Non-specific Low Back Pain
The goal of this clinical trial is to compare Cognitive Functional Therapy (CFT) with Kinetic Control Training (KCT) in participants with non-specific low back pain.
- Trial name
- LBP (NCT07282925)
- Testing
- Cognitive Functional Therapy, Kinetic Control Training
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Suicidal Ideation
Improving Caregivers' Ability to Manage Life Stress
The COVID-19 pandemic has led to increased caregiving demands for caregivers of Veterans with dementia. Dementia caregivers are particularly at-risk for depression and anxiety, known risk factors for increased suicidality.
- Trial name
- NCT05539352
- Testing
- Problem Solving Therapy (PST) plus EUC
- Where
- United States
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, Attention Impaired
The Effect of Body Percussion Training on Neuromotor Performance, Attention, and Functionality in Adolescents With Mild Intellectual Disability
The aim of this randomized controlled trial is to investigate the effects of group-based rhythm-based body percussion training on neuromotor performance, attention, and functionality in adolescents with mild intellectual…
- Conditions
- Mild Cognitive Impairment, Attention Impaired, Adolescent Development
- Trial name
- NCT07554144
- Testing
- Rhythm-based body percussion training group, Control group (passive listening) group
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Kutahya Health Sciences University
Mild Cognitive Impairment (MCI), Subjective Cognitive Complaints (SCCs)
EARLY-COGN^3 - Smart Digital Solutions for EARLY Treatment of COGnitive Disability: a Neuropsychological, Neurophysiological and Neurobiological Perspective in Chronic Neurological Diseases - PNRR-MCNT2-2023-12377069
The increase in life expectancy in recent decades has led to a large number of people living into old age and an increased risk of developing Chronic Neurological Diseases (CNDs) such as neurodegenerative diseases.
- Conditions
- Mild Cognitive Impairment (MCI), Subjective Cognitive Complaints (SCCs), Parkinson Disease
- Trial name
- EARLY-COGN^3 (NCT06657274)
- Testing
- RICORDO-DTx, Home-based unstructured cognitive stimulation
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Autism, Intellectual Disability
Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Trial name
- NCT02914951
- Testing
- Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Neurofibromatosis Type 1
Reading Disability in Children With NF1
A national, multicenter, randomized, transverse clinical trial, estimating the existence of phonological deficits in children with NF1 children compared with control children without NF1 with the same reading level.
- Trial name
- NCT02397967
- Testing
- Neuropsychological assessments
- Where
- 6 sites in France
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Down Syndrome (DS)
Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool
Epigallocatechin-3-gallate (EGCG), the major catechin in green tea, is postulated to modulate dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) and amyloid beta precursor protein (APP) gene overexpression in…
- Trial name
- NCT01699711
- Testing
- Epigallocatechin-3-gallate (EGCG)
- Where
- Spain
- Volunteers
- 87 people
- Sponsor
- Parc de Salut Mar
Intellectual Disability, Mild
Effects of a 12-Week Pickleball Training Program on Cognitive and Motor Skills in Adolescents With Mild Intellectual Disability
This study aims to investigate the effects of a 12-week pickleball training program on cognitive and motor outcomes in adolescents with mild intellectual disability.
- Trial name
- PBID-12 (NCT07586722)
- Testing
- Pickleball Training Intervention Group, Standard Special Education Curriculum
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Elif Top
Physical Disability, Cognitive Dysfunction
Evaluation of mediVR-KAGURA Guided Therapy
The objective is to evaluate mediVR-KAGURA guided therapy for the treatments of physical and cognitive dysfunctions regardless of baseline disease in a prospective interventional design.
- Trial name
- NCT04562662
- Testing
- mediVR KAGURA
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Japan Society of Clinical Research
Enhancing Early Language and Cognitive Development in Toddlers Through a Culturally Adapted Home-based Parent Intervention
Home-Based Language and Cognitive Intervention for Arab Toddlers in Israel
This study evaluates the effectiveness of a culturally adapted, home-based program designed to improve language and cognitive development in Arab toddlers in Israel.
- Trial name
- CAHBI-T (NCT07233525)
- Testing
- Culturally Adapted Parent-Implemented Intervention, Child Health Education Sessions
- Where
- Israel
- Volunteers
- 240 people
- Sponsor
- Hillel Yaffe Medical Center
Concussion, Mild, Post Concussion Symptoms
RTL Concussion Communication
This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL).
- Conditions
- Concussion, Mild, Post Concussion Symptoms, Cognitive Impairments, Cognitive Impairments, Mild
- Trial name
- NCT06212726
- Testing
- InjureFree
- Sponsor
- University of Florida
Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder
The Effects of Yoga on Sensory, Motor, Cognitive Skills, and Perceived Stress in Children With Developmental Coordination Disorder
This clinical study aims to investigate the effects of yoga on children with Developmental Coordination Disorder (DCD). DCD is a condition that can make it difficult for children to perform everyday activities, as it affects…
- Conditions
- Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder, Sensory Integration Disorder, Perceived Stres Level
- Trial name
- NCT07547514
- Testing
- Yoga intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
Down Syndrome, Cognitive Dysfunction
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17
The purpose of this study is to determine the efficacy and safety of donepezil hydrochloride (Aricept) in the treatment of the cognitive dysfunction shown by children with Down syndrome, aged 11 to 17.
- Trial name
- NCT00754052
- Testing
- Aricept (donepezil hydrochloride)
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Eisai Inc.
Williams Syndrome, Autism Disorder
Research on the Molecular Mechanism of Cognitive Differences Between Williams Syndrome and Autism Spectrum Disorder
Williams Syndrome (WS) is a rare neurodevelopmental disorder, usually caused by microdeletions of approximately 26 genes in the long arm (7q11.23) region of chromosome 7.
- Trial name
- WS and ASD (NCT07509879)
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University