Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Cognitive Dysfunction, Physical Inactivity
Effects of Intradialytic Cognitive and Physical Exercise Training on Functional Status of Hemodialysis Patients
The aim of this study is to investigate the effect of cognitive training combined with physical exercise on cognitive function, physical performance and frailty indicators in the hemodialysis population.
- Conditions
- Cognitive Dysfunction, Physical Inactivity, Chronic Kidney Diseases
- Trial name
- DIAKOG (NCT05150444)
- Testing
- Cognitive and physical exercise training
- Where
- Slovenia
- Volunteers
- 44 people
- Sponsor
- University Medical Centre Ljubljana
Obesity, Cognitive Disorder
Emotional Regulation, Cognition, Impulsivity and Reward System in Obesity: A Prospective Study of Bariatric Surgery
This research investigates obesity and associated psychiatric symptoms and disorders in a wide range of perspectives, to demonstrate the effects of obesity on the brain.
- Trial name
- NCT03528044
- Testing
- Bariatric surgery
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Koç University
Panic Disorder, Agoraphobia
A Clinical Trial to Evaluate the Efficacy and Safety of Meltz, a Digital Therapeutic Device, for Improving Panic Symptoms in Patients With Panic Disorder
i. This randomized clinical trial will evaluate the efficacy and safety of Meltz, a digital therapeutic device that provides cognitive behavioral therapy (CBT) for adults with panic disorder. ii.
- Trial name
- Meltz (NCT07892885)
- Testing
- Meltz
- Volunteers
- 120 people
- Sponsor
- AIMNEXT
Alzheimer's Disease, Dementia
Safety and Efficacy Study of Ladostigil in Mild to Moderate Probable Alzheimer's Disease
For many, Alzheimer's disease is the number one medical issue facing our aging society. It is a late onset neurodegenerative disease, frequently under diagnosed, that impairs memory and cognitive performance.
- Conditions
- Alzheimer's Disease, Dementia, Memory Loss, Cognitive Impairment
- Trial name
- NCT01354691
- Testing
- ladostigil hemitartrate
- Where
- 19 sites in Austria, Croatia and 3 more
- Volunteers
- 200 people
- Sponsor
- Avraham Pharmaceuticals Ltd
Chronic Fatigue Syndrome
A Complex Intervention for Chronically Fatigued Lymphoma Survivors
The present study is a randomized controlled trial (RCT) with an overall objective to examine the effect of an interdisciplinary complex intervention on the level of fatigue in lymphoma survivors with chronic fatigue.
- Trial name
- NCT05130099
- Testing
- Interdisciplinary complex intervention
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
COVID-19, Symptoms and Signs
The Effect of Mobile Health Application Based on Omaha System on Symptoms and Quality of Life in COVID-19 Patients
Purpose: The aim of this study is to evaluate the effects of nursing interventions made with a mobile health application (COVOS) developed based on the Omaha System on the physical, psychosocial and cognitive symptoms and quality…
- Conditions
- COVID-19, Symptoms and Signs, Quality of Life
- Trial name
- NCT05258734
- Testing
- COVOS app, Standard Care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Alzheimer's Disease
A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)
The purpose of the study is to investigate the effect of bepranemab versus (vs) placebo on the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) up to Week 80 in study participants with prodromal or mild Alzheimer's Disease…
- Trial name
- NCT04867616
- Testing
- Bepranemab
- Where
- 103 sites in United States, Belgium and 8 more
- Volunteers
- 466 people
- Sponsor
- UCB Biopharma SRL
Diabetes Type 1
Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Older people with diabetes have a higher risk for cognitive impairment and for physical disability whether this may be effected by an improvement in glucose indices is unknown.
- Trial name
- 780G65+ (NCT06207838)
- Testing
- MiniMed 780G system
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
Metastatic Renal Cell Cancer, GIST
Evaluation of Cognitive Function of Patients With Sunitinib or Sorafenib
Patients with advanced kidney cancer or GIST (Gastro Intestinal Stromal Tumor: this is a tumor of the intestines) may be eligible for treatment with one of the following drugs: sunitinib (Sutent ®) or sorafenib (Nexavar ®).
- Trial name
- NCT01246843
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
Parkinson Disease
Effect of Physical Rehabilitation in Patients With Parkinson's Disease
This is a prospective study. The aim of this study is to investigate the effect of exercise retraining on cardiorespiratory parameters, postural balance, sociopsychological variables, and cognitive function in subjects with…
- Trial name
- NCT06021834
- Testing
- rehabilitation
- Volunteers
- 40 people
- Sponsor
- Faculty of Medicine, Sousse
Stroke
Evaluation of the Effectiveness and Safety of ABAStroke
The aim of the project is to confirm the effectiveness and safety of the ABAStroke technology, which uses the principles of Applied Behavior Analysis (ABA) in the rehabilitation of cognitive deficits in patients after strokes.
- Trial name
- NCT05979324
- Testing
- ABAStroke Digital Therapeutics
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- ABAStroke Sp. z o.o.
Post Intensive Care Syndrome (PICS)
Post Intensive Care Accelerometery to Study and Support Recovery Outcomes
The primary purpose of this study is to find out whether a wrist-worn activity monitor can help healthcare professionals understand how people recover after they leave the intensive care unit (ICU), where they were cared for when…
- Trial name
- PICASSO (NCT07466446)
- Where
- 3 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Panic Disorder, Agoraphobia
Physical Activity and Cognitive Behavioural Therapy in Panic Disorder and Agoraphobia
Physical activity (treadmill) prior to in-vivo exposure supports the effect of cognitive behavioural therapy in patients with panic disorder and agoraphobia.
- Trial name
- NCT01928810
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 78 people
- Sponsor
- Charite University, Berlin, Germany
Physical Disability
Norwegian Psychomotor Physiotherapy in Patients With Long-lasting Musculoskeletal Pain.
The aim is to examine the effect of Norwegian Psychomotor Physiotherapy (NPMP) in employees with long-lasting musculoskeletal pain compared to employees receiving Cognitive Patient Education in combination with active individual…
- Trial name
- NPMP (NCT02482792)
- Testing
- Norwegian Psychomotor Physiotherapy, Cognitive Patient Education and PT
- Where
- Norway
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tove Dragesund
Alzheimer's Disease
Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease
The purpose of this Phase 1/Phase 2 study is to evaluate how the body handles the drug and the drug's effect on the body of participants with mild cognitive impairment (MCI) due to Alzheimer's Disease (AD) or mild AD and who test…
- Trial name
- NCT01561430
- Testing
- LY2886721
- Where
- 34 sites in United States, Italy and 3 more
- Volunteers
- 70 people
- Sponsor
- Eli Lilly and Company
Schizophrenia, Balance; Distorted
Comparison of the Effects of Physical Activity and Virtual Reality Training in Patients With Schizophrenia
The current study aims to compare the effects of physical activity and Virtual Reality training on physical function, cognition and quality of life in patients with Schizophrenia.
- Conditions
- Schizophrenia, Balance; Distorted, Cognitive Impairment
- Trial name
- NCT07173465
- Testing
- Virtual Reality (VR), Physical Activity (PA group), occupational therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Yeditepe University
Ischemic Stroke, Post-Stroke Cognitive Impairment
MSC Secretome Therapy for Cognitive Recovery After Subacute Ischemic Stroke
Post-stroke cognitive impairment can limit rehabilitation, independence, and quality of life after ischemic stroke. This pilot randomized controlled trial evaluates whether mesenchymal stem cell-derived secretome, given in…
- Trial name
- NCT07731087
- Testing
- Umbilical Cord Mesenchymal Stem Cell-Derived Secretome, Standard Stroke Care and Rehabilitation
- Where
- Indonesia
- Volunteers
- 70 people
- Sponsor
- Jumraini Tammasse
Cognitive Impairment
The Study of Jian Pi Yi Shen Hua Tan Granules in Cognitive Impairment After Acute Cerebral Infarction
The purpose of this study is to determine whether the chinese medicine Jian Pi Yi Shen Hua Tan granules is effective in the treatment of cognitive impairment after acute cerebral infarction .
- Trial name
- NCT02641886
- Testing
- Jian Pi Yi Shen Hua Tan Granules
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
Patient With Bipolar Disorder, Euthymic Status
Cognitive Remediation on Patients With Bipolar Disorder and Memory Complaints
Bipolar disorder is a major health concern. Intercritical periods are marked with residual symptoms, both thymic and cognitive, which affects quality of life of patients, but also the quality of observance.
- Conditions
- Patient With Bipolar Disorder, Euthymic Status, Wirh Memory Complaints
- Trial name
- COGMED (NCT02988518)
- Testing
- COGMED program
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Montpellier
Mild Cognitive Impairment, Obstructive Sleep Apnea
Evaluation of Trazodone in OSA-MCI
Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disease. Before progressing to AD, individuals may experience mild cognitive impairment (MCI).
- Trial name
- NCT05209035
- Testing
- Trazodone
- Where
- Hong Kong
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong