Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Breast Cancer Female
Evaluating and Following Breast Cancer Patients in a Better Way
The current observational study aims at analysing current semiology on breast cancer patients aiming at noting indicators and signs with significant relationship with the disease outcomes.
- Trial name
- EFBCancer (NCT03831308)
- Testing
- clinical and physical assessment
- Volunteers
- 200 people
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Coronary Artery Disease, Smoking Cessation
Effects of Cognitive-behavioral Education and Exercise Interventions on Smoking Cessation
The purpose of the study is to adopt the Trans-theoretical Model to facilitate step-by-step changes in a patient's smoking behavior and explore the effect of "Cognitive-Behavioral Education Course" and "Exercise Program" on…
- Trial name
- NCT05079958
- Testing
- cognitive-behavioral education, 12-week brisk walking
- Where
- Taiwan
- Volunteers
- 172 people
- Sponsor
- Cathay General Hospital
Traumatic Brain Injury (TBI) Patients, Cognitive Impairment
Mindfulness-Integrated Neuropsychotherapy for Traumatic Brain Injury: A Mixed-Methods Evaluation of Cognitive and Psychosocial Recovery
The goal of this clinical trial is to test the effectiveness of Integrative Mindfulness Enhanced Neuropsychotherapy (IMENP) in improving neurocognitive functioning and wellbeing among adults aged 18 to 44 years with mild to…
- Conditions
- Traumatic Brain Injury (TBI) Patients, Cognitive Impairment, Depression Disorder, Fatigue Severity Scale
- Trial name
- IMENP (NCT07874685)
- Testing
- Integrative Mindfulness Enhanced Neuropsychotherapy (IMENP)
- Where
- India
- Volunteers
- 68 people
- Sponsor
- University of Madras
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Major Depression
Effectiveness of Repetitive Transcranial Magnetic Stimulation in Depressed Patients
The purpose of this study is to evaluate clinical efficacy (affective and cognitive) in patients with moderate depression between TMS over the left Dorsolateral Prefrontal Cortex (DLPFC) with simulated TMS, as well as clinical…
- Trial name
- NCT02213016
- Testing
- Transcranial Magnetic Stimulation
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Nacional Autonoma de Mexico
Dementia
Enhancing Mobility and Mental Health in Dementia Patients
This study aims to evaluate the effect of a multidisciplinary six-minute walking group and activities on patients with dementia\'s physical activity levels, mobility, anxiety, and cognitive function.
- Trial name
- NCT06611202
- Testing
- Exercise, Clonazepam
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Oxleas NHS Foundation Trust
Diabetes Mellitus, Type 2
Cognitive Behavioral Therapy for African Americans With Uncontrolled Type-2 Diabetes
The main purpose of the study is to assess the feasibility and acceptability of a Culturally-Tailored Cognitive Behavior intervention (CT-CB) for African American patients with uncontrolled Type 2 diabetes.
- Trial name
- NCT03562767
- Testing
- Group-based Cognitive Behavioral Intervention, Web-based Cognitive Behavioral Intervention, Usual Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Chronic Renal Insufficiency, Chronic Kidney Failure
Behaviour and Cognitive Evaluation for Dialysis Elderly Patients (BCDE)
The trial is a multicenter, prospective, randomized, open study. A total of 500 elderly patients aged over 75 years with renal insufficiency stage 5 will be included in the study after signed informed consent.
- Conditions
- Chronic Renal Insufficiency, Chronic Kidney Failure, Aged
- Trial name
- BCDE (NCT01225458)
- Testing
- shorter tests, initial complete geriatric tests, follow-up complete geriatric tests
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Breast Cancer
Evaluation of Cognitive Management for Chemobrain in Patients Treated for Breast Cancer.
This project will investigate the efficacy of a cognitive remediation programme in patients treated for breast cancer. patients will be randomized between "no intervention" and "intervention programme".
- Trial name
- e-ONCOGITE (NCT05690828)
- Testing
- Cognitive remediation
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Institut Bergonié
Fibromyalgia
A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.
The study is designed to assess if esreboxetine can improve the cognitive function of patients with fibromyalgia. Cognitive function is defined as the ability to concentrate, remember things and make decisions or problem solve.
- Trial name
- NCT00752505
- Testing
- Esreboxetine
- Where
- 7 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Pfizer
Patients Treated for Cancer
Cancer Related Cognitive Impairment
Various recent scientific data testify to the cognitive deficiencies of cancer patients, called Cancer-Related Cognitive Impairments (CRCI) (Noal, Daireaux \& Joly, 2010).
- Trial name
- APACO (NCT03949322)
- Testing
- Adapted Physical Activity Program
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Institut Cancerologie de l'Ouest
Type 2 Diabetes Mellitus, Obesity
Effects of Liraglutid, Dapagliflozin and Acarbose on the Cognitive Function, Olfactory Function, and Odor-induced Brain Activation in Overweight/Obese T2DM Patients Controlled Inadequately With Metformin Monotherapy.
This is a prospective, randomized, open label, parallel, 16-week study to explore and evaluate the therapeutic effects of liraglutid, dapagliflozin and acarbose on the cognitive function, olfactory function, and odor-induced…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Cognitive Impairment
- Trial name
- NCT03961659
- Testing
- Liraglutid, Dapagliflozin, Acarbose
- Where
- China
- Volunteers
- 87 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Non-Alcoholic Fatty Liver Disease, Cognitive Impairment
Cognitive Assessment and Brain Function Evaluation in Patients With Non-alcoholic Fatty Liver Disease
The purpose of this study is to explore the relationship between Non-alcoholic fatty liver disease and cognitive impairment and evaluate the effect of metabolic surgery or lifestyle intervention on cognition.
- Trial name
- NCT05563259
- Testing
- Cognitive assessment, functional magnetic resonance imaging
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yan Bi
Alzheimer Disease
Evaluation of the Effect of Wismemo on Alzheimer's Dementia Patients
The present studies demonstrated that pro-inflammation, systemic oxidative stress and dysfunction in the brain-gut microbiota axis were involved in Alzheimer's disease (AD) pathogenesis.
- Trial name
- NCT04094129
- Testing
- Wismemo
- Sponsor
- GenMont Biotech Incorporation
Lupus Erythematosus, Systemic
Interactive Digital Technology to Assess and Improve Cognitive Dysfunction in Patients With Systemic Lupus Erythematosus
The purpose of this study is to evaluate whether a short interactive video game device is associated with performance on standard measures of attention and problem solving in patients with systemic lupus erythematosus(SLE).
- Trial name
- NCT03746197
- Testing
- Project EVO Multi- Treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Jewish Health
Multiple Sclerosis, Performance Enhancement
Effects of DHA in Patients With Multiple Sclerosis
This clinical trial will investigate the effects of combining therapeutic exercise with DHA supplementation in 100 patients with multiple sclerosis using a randomized controlled design.
- Conditions
- Multiple Sclerosis, Performance Enhancement, Supplemental Nutrition Assistance Program Education, Strength Outcomes
- Trial name
- DHAME (NCT07346703)
- Testing
- Docosahexaenoic Acid (DHA) Dietary Supplement, Sunflower Oil
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Chronic Obstructive Pulmonary Disease (COPD), Chronic Obstructive Lung Disease
Mindfulness-based Cognitive Therapy for Chronic Obstructive Pulmonary Disease
The purpose of the study is to determine the efficacy of mindfulness-based cognitive therapy (MBCT) as an add-on to pulmonary rehabilitation (treatment as usual, TAU) in chronic obstructive pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Chronic Obstructive Lung Disease, Chronic Obstructive Airway Disease, Chronic Bronchitis
- Trial name
- NCT02042976
- Testing
- Mindfulness-based cognitive therapy, Pulmonary rehabilitation
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- University of Aarhus
Fatigue
Sleep and Training Aspects in Dialysis Fatigue - Exercise Intervention
The purpose of the current study is to investigate whether changes in patients' sleep quality and quantity will be followed by improvements in parameters related to physical and mental fatigue in patients receiving hemodialysis…
- Trial name
- StandFirm (NCT01721551)
- Testing
- Exercise, Usual Treatment
- Where
- 3 sites in Greece
- Volunteers
- 50 people
- Sponsor
- University of Thessaly
Mild Cognitive Impairment (MCI), Alzheimer Dementia (AD)
Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study
Recent studies have identified an association between Alzheimer's Disease (AD) and an expansion of DNA content in the brain (prefrontal cortex).
- Trial name
- SONATAS (NCT07210528)
- Testing
- Emtricitabine (FTC), Descovy® (TAF/FTC)
- Where
- Singapore
- Volunteers
- 48 people
- Sponsor
- National University Hospital, Singapore
Dementia, Mild, Cognitive Disorder Mild
The Pilot Study of Medical Device-Neuclare for Patients With Mild Cognitive Disorder and Early Dementia
This clinical trial aims to explore the effectiveness and safety of cognitive function improvement of Neuclare, a science medical device, for patients with mild cognitive impairment and early Alzheimer's disease.
- Trial name
- NCT05633095
- Testing
- Neuclare
- Where
- 2 sites in South Korea
- Volunteers
- 20 people
- Sponsor
- Deepsonbio