Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Heart Failure, Rural Health
Forge AHEAD: Feasibility of Yoga to Improve Cognitive Function
The investigators will conduct a two-phase pilot study to test the feasibility and acceptability of a 12-week Chair Yoga intervention for 20 heart-failure patients.
- Conditions
- Heart Failure, Rural Health, Engagement, Patient
- Trial name
- Forge AHEAD (NCT07489105)
- Testing
- Yoga group
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Auburn University
Rheumatoid Arthritis
STudying Ageing in Rheumatic Diseases (STAR)
The primary objective of the STAR study is to investigate how measures of disease activity and measures for cognition, physical activity and performance behave in ageing population controls and patients with rheumatoid arthritis…
- Trial name
- NCT05463666
- Testing
- Rheumatoid arthritis
- Where
- Netherlands
- Volunteers
- 840 people
- Sponsor
- Maastricht University Medical Center
Physical Activity
Training Intervention in Heart Failure and Frail Elderly Population
There is enough scientific evidence of the benefits detection of frailty in patients with heart failure, which is an important prognostic factor.
- Trial name
- TIHFEP (NCT02365155)
- Testing
- Multicomponent training intervention., Nutrition intervention, Cognitive intervention
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital de la Ribera
Mild Cognitive Impairment (MCI)
Nutritional Intervention With the Dietary Supplement, Immunocal® in MCI Patients: Promotion of Brain Health
Alzheimer disease (AD) is a dementing illness characterized by progressive neuronal degeneration, gliosis, and the accumulation of intracellular inclusions and extracellular deposits of amyloid in discrete regions of the basal…
- Trial name
- NCT03448055
- Testing
- Immunocal
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Immunotec Inc.
Postcomatose Unawareness State, Minimally Conscious State
Eye Tracking Technology in the Diagnosis of Neurological Patients
Demonstrating that diagnostics of the state of consciousness and cognitive functions of patients with consciousness disorders performed using C-Eye X (based on eye-tracking technology) allows a more objective assessment of state…
- Conditions
- Postcomatose Unawareness State, Minimally Conscious State, Vegetative State, Disorder of Consciousness
- Trial name
- NCT05536921
- Where
- 5 sites in Poland
- Volunteers
- 90 people
- Sponsor
- AssisTech Sp. z o.o.
BDNF, Cognitive Functions
BDNF Levels in Cancer Patients Receiving Chemotherapy
Cognitive impairment following chemotherapy is defined as chemotherapy-induced cognitive impairment (CCIID). CCIID, which significantly reduces the quality of life of cancer patients receiving chemotherapy, develops as a result…
- Conditions
- BDNF, Cognitive Functions, Chemotherapy
- Trial name
- CARE (NCT07019324)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Cemre Aydeğer
Alzheimer's Disease, Parkinson's Disease
Evaluation of a Diet in Patients With Senile Dementia
The most common symptoms associated to senile dementia disease are confusion about schedules, hyperactivity... In this sense, these patients have frequently poor nutrition, resulting in malnutrition problems or malnutrition high…
- Conditions
- Alzheimer's Disease, Parkinson's Disease, Senile Dementia
- Trial name
- SUPRESSI (NCT01192529)
- Testing
- Supressi. T-Diet plus Range, High Protein. T-Diet plus Range
- Where
- 3 sites in Spain
- Volunteers
- 184 people
- Sponsor
- Vegenat, S.A.
Restless Legs Syndrome, Anxiety
Investigation of the Effects of Different Exercise Programs in Patients With Restless Legs Syndrome.
Restless leg syndrome (RLS) is a very common neurological condition characterized by an uncontrollable desire to move the legs. Due to the traumatic effect of RLS on morbidity, the patient is negatively affected in many different…
- Conditions
- Restless Legs Syndrome, Anxiety, Sleep
- Trial name
- NCT04711993
- Testing
- Aerobic exercise, Stretchin exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Gulhane School of Medicine
Mild Cognitive Impairment, Idiopathic Membranous Nephropathy
the Effects of Different Treatment Schemes on Cognitive Function of Patients With Idiopathic Membranous Nephropathy
This study intends to apply prospective, open, single-center, randomized controlled study to evaluate the cognitive status of patients with Idiopathic membranous nephropathy and the influence of different treatment schemes on the…
- Trial name
- NCT06245707
- Testing
- prednisone,methylprednisone and cyclophosphamide, Rituximab
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Beijing Friendship Hospital
Cognitive Impairment, Mild, Cognitive Dysfunction
MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients
Accumulating evidence indicates that inflammation is prominent both in the blood and central nervous system (CNS) of Alzheimer's disease (AD) patients.
- Conditions
- Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque, Neurodegeneration
- Trial name
- MCLENA-1 (NCT04032626)
- Testing
- Lenalidomide 10 mg
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Covid19
Early Cognitive Assessment and Evolutionary Monitoring of Patients With Severe ARDS on COVID-19 Pneumonia Requiring Mechanical Ventilation
The new coronavirus pandemic responsible for the severe acute respiratory syndrome SARS-CoV2 requires, in its severe forms, the use of invasive ventilation in intensive care.
- Trial name
- CognitiVID (NCT04468035)
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Stroke, Hemiparesis
Telerehabilitation Through Serious Games in Virtual Reality in a Stroke Population (AutoRReVi)
After a stroke, individuals present with motor and/or cognitive impairments. These impairments limit activity, restrict participation and affect quality of life.
- Conditions
- Stroke, Hemiparesis, Cognitive Impairment, Healthy Subjects
- Trial name
- AutoRReVi (NCT04694833)
- Testing
- Motor and cognitive virtual reality-based assessments, Motor and cognitive virtual reality-based serious games
- Where
- Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Breast Cancer
Impact of Cognitive Impairment on Chronic Pain in Breast Cancer
Breast cancer treatments are associated with frequent and sometimes severe adverse effects that may significantly impair quality of life and lead to functional disability.
- Trial name
- Cactus (NCT07877376)
- Testing
- Evaluation of cognitive functions in patients with beast cancer
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Nadine ATTAL
Silent Stroke, Cognitive Decline
Detection and Neurological Impact of Cerebrovascular Events in Cardiac Surgery Patients
The investigators conducted a prospective observational pilot study to explore the incidence of peri-operative covert strokes (detected by brain MRI) and the potential impact on delirium and cognitive decline in post-operative…
- Trial name
- NCT04241289
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Population Health Research Institute
Depressive Symptoms, Diabetes Mellitus
Evaluation of a Diabetes-specific Cognitive Behavioural Treatment for Subthreshold Depression
This work is supported by the "Kompetenznetz Diabetes mellitus (Competence Network for Diabetes mellitus)" funded by the Federal Ministry of Education and Research (FKZ 01GI0809).
- Trial name
- NCT01009138
- Testing
- Diabetes-Specific CBT (DS-CBT), Standard Diabetes Education
- Where
- Germany
- Volunteers
- 214 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Mucopolysaccharidosis (MPS), Hunter Syndrome
Observational Study to Evaluate Neurodevelopmental Status in Pediatric Patients With Hunter Syndrome (MPS II)
Hunter syndrome (Mucopolysaccharidosis II, [MPS II]) is a rare, genetically linked lysosomal storage disease (LSD) caused by deficiency of the enzyme, iduronate-2-sulfatase (I2S).
- Trial name
- NCT01822184
- Where
- 7 sites in United States, Argentina and 3 more
- Volunteers
- 100 people
- Sponsor
- Shire
Schizophrenia
Evaluation of Dorsal Visual Stream in Patients With Schizophrenia
Schizophrenia patients in comparing to normal controls show decreased ability to identify objects with decreased level of fragmentation, a task that is associated with magnocellular pathway function.
- Trial name
- NCT01378403
- Where
- Israel
- Volunteers
- 22 people
- Sponsor
- Sheba Medical Center
Cognitive Impairment, Memory Complaint
Performance of AclarusDx® a Blood-Based Transcriptomic Test for AD, in French Patients Newly Referred to a Memory Center
The purpose of this study is to assess the performance of AclarusDx™, an investigational blood test detecting gene expression information, and intended to help physicians in making an Alzheimer's Disease diagnosis in patients…
- Conditions
- Cognitive Impairment, Memory Complaint, Clinical Investigation in Memory Centers
- Trial name
- DIALOG (NCT02221661)
- Volunteers
- 606 people
- Sponsor
- Diaxonhit
Hip Fractures, Cognitive Impairment
Hip Fracture Exercise and Rehabilitation Post Hip Fracture Study
This pilot study will look at whether it is possible to give better physical therapy to people with cognitive limitations who have had a hip fracture.
- Trial name
- HipERS (NCT03247205)
- Testing
- HipERS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Circadian Rhythm Disorders, Cancer
A Feasibility Trial for Circadian Rest-activity Rhythm Disorders in Cancer (RALI)
Circadian rest-activity rhythm disorders are common in patients with cancer, particularly in advanced disease. A recent international e-Delphi study has outlined recommendations for the assessment and reporting of the disorder…
- Trial name
- NCT06329479
- Testing
- Cognitive behavioural therapy for Insomnia (CBT-I), Bright Light Therapy, Individualised activity plan
- Where
- 2 sites in Ireland
- Volunteers
- 30 people
- Sponsor
- University of Dublin, Trinity College