Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Cancer, Insomnia
Improving Sleep Among Cancer Patients: Comparison Between Physical Activity and Self-administered Cognitive-behavioral Therapy (CBT)
It has been suggested that the practice of physical exercise can improve sleep, but few studies have investigated this issue in the context of cancer, despite the proven benefits of exercise in this population.
- Trial name
- NCT02774369
- Testing
- Physical exercise, Cognitive-behavioral therapy
- Volunteers
- 41 people
- Sponsor
- CHU de Quebec-Universite Laval
Mild Cognitive Impairment Due to Alzheimer's Disease
Evaluation of Safety of Contraloid Acetate in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease
Patients with mild cognitive impairment due to Alzheimer's disease (MCI due to AD) are at high risk to develop Alzheimer´s dementia.
- Trial name
- NCT04711486
- Testing
- Contraloid acetate
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Charite University, Berlin, Germany
Delirium
Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)
Many individuals experience an acute change in thinking and reasoning skills after surgery. This is called post-operative delirium (PD). PD symptoms typically start 1-3 days after surgery.
- Trial name
- NCT02230605
- Testing
- Mini-Mental State Examination, Self-Administered Gerocognitive Examination, Geriatric Depression Scale
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Neck Pain, Chronic Pain Syndrome
Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain
The purpose of this study is to test whether a physiotherapy intervention containing pain management, general training and specific neck exercises can improve function for patients with chronic neck pain.
- Trial name
- WADNECXT (NCT01431261)
- Testing
- Education and training, Pain management
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- University of Southern Denmark
Stroke
Evaluation of a Haptic Glove for Assessing Tactile Perception in Post-Stroke Patients
The aim of the SCORES Haptic Glove Study is to assess the technical features, safety, and reliability of a sensor-equipped glove designed to evaluate tactile perception.
- Trial name
- SCORES-glove (NCT06643273)
- Testing
- Robotic rehabilitation, Conventional rehabilitation
- Where
- 3 sites in Italy
- Volunteers
- 126 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Attention Disorder
Analysis of the Impact of a Temporo-spatial Reorientation Tool on the Speed of Improvement of Confusional Syndrome
Confusion syndrome is defined by attentional disorders and disorganization of cognitive functions that are acute and reversible. There are patient-specific predisposing factors and precipitating factors.
- Trial name
- Rob'Gazette (NCT06498297)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Aneurysmal Subarachnoid Hemorrhage, Neurobehavioral Manifestations
Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin
A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients with Significant Hemorrhage Burden.
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Neurobehavioral Manifestations, Vasospasm, Intracranial, Intracranial Aneurysm
- Trial name
- ASTROH (NCT02501434)
- Testing
- Continuous Low-Dose IV Unfractionated Heparin Infusion
- Where
- 9 sites in United States
- Volunteers
- 88 people
- Sponsor
- Robert F. James
Vascular Cognitive Impairment
A Clinical Trial to Evaluate the Efficacy and Safety of Choline Alfoscerate in Vascular Cognitive Impairment Patients
This is a multi-center, randomized, double-blind, placebo-controlled, Phase IV Trial to evaluate the efficacy and safety of Choline Alfoscerate compared to placebo in Mild Cognitive Impairment Patients with Cerebrovascular Disease
- Trial name
- NCT05050604
- Testing
- Choline Alfoscerate 400mg
- Where
- South Korea
- Volunteers
- 418 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Traumatic Brain Injury
Validation Study of Simplified Chinese Version of LOTCA Scale in the Assessment of Cognitive Impairment in Patients with Traumatic Brain Injury
In this study, 300 patients aged ≥18 years old with traumatic brain injury (case group) and hospitalized patients without central nervous system disease or their family members and accompanying staff (control group) were selected…
- Trial name
- NCT06850584
- Testing
- Observation
- Where
- 4 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nanjing Broad Biopharmaceutical Ltd.
Sleep Hygiene, Sarcopenia
Sleep Hygiene, Sarcopenia, and Cognitive Function in Respiratory Disease
We aim to clarify the relationship between sleep hygiene and the onset of sarcopenia or cognitive dysfunction using sleep time, arousal, and sleep quality as indicators in COPD or IPF patients, and clarify the effects of sleep…
- Conditions
- Sleep Hygiene, Sarcopenia, Cognitive Function, COPD
- Trial name
- NCT05193136
- Where
- Japan
- Volunteers
- 120 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
COVID 19, Oxydative Stress
Oxidative Stress and Cognitive Dysfunction After COVID-19
This observational cohort study will investigate the association between oxidative stress biomarkers and post-COVID-19 cognitive impairment.
- Conditions
- COVID 19, Oxydative Stress, Cognitive Impairments
- Trial name
- NCT07029048
- Testing
- Standard Post-COVID Rehabilitation Program
- Where
- Kazakhstan
- Volunteers
- 45 people
- Sponsor
- Karaganda Medical University
Mild Cognitive Impairment (MCI), Alzheimer Disease
Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation
The goal of this Phase 2 MCI study is to determine whether 1.0 mg/kg XPro1595 is superior to placebo at improving measures of cognition, functioning and brain quality in individuals with MCI and biomarkers associated with…
- Conditions
- Mild Cognitive Impairment (MCI), Alzheimer Disease, Dementia, Brain Diseases
- Trial name
- NCT05321498
- Testing
- XPro1595
- Sponsor
- Inmune Bio, Inc.
Brain Injury Traumatic Mild
Evaluation of the Impact of a Dietary and Nutritional Intervention on Persistent Post-concussive Symptoms
Concussions affect thousands of Canadians every year. Although the effects are usually temporary, 10-15% of adults experience persistent symptoms likely to last several weeks or even months.
- Trial name
- NCT05589064
- Testing
- Experimental: Dietetic counseling, Active Comparator: Omega-3, vitamin D3 and creatine monohydrate, Other : Physiotherapy treatment
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Universite de Moncton
Unrecognized Condition
The Influence of Rhythm, Cognitive Task and Physical Activity on the Cardiac ANS in Chronic Stroke Patients
Autonomic dysfunction is a common complication of stroke that may lead to poor rehabilitation outcomes and to increase in mortality.
- Trial name
- NCT03016416
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Mild Cognitive Impairment, Alzheimer Disease 1
Safety and Feasibility of Exablate Blood-Brain Barrier Disruption for Mild Cognitive Impairment or Mild Alzheimer's Disease Undergoing Standard of Care Monoclonal Antibody (mAb) Therapy
The purpose of this study is to assess the safety and feasibility of administering standard of care monoclonal antibody (mAb) infusion therapy in combination with opening the blood-brain barrier with the Exablate Model 4000 Type…
- Trial name
- NCT05469009
- Testing
- Aducanumab, Exablate Model 4000 Type 2, Lecanemab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ali Rezai
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer
This phase II trial studies the effect of a digital application (app), BNT001, on cognitive-behavioral stress management in patients with stage I-III breast or lung cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- BNT001 (NCT04705025)
- Testing
- Cognitive Behavior Therapy, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Mild Cognitive Impairment (MCI), Mild Dementia
Study to Evaluate the Efficacy and Safety of KDS2010 in Patients With Alzheimer's Disease With Mild Cognitive Impairment and Mild Dementia Due to Alzheimer's Disease
A randomized, double-blind, placebo-controlled, dose-finding Phase 2a clinical trial will be conducted to evaluate the efficacy and safety of KDS2010 in patients with Mild Cognitive Impairment (MCI) due to Alzheimer's disease…
- Conditions
- Mild Cognitive Impairment (MCI), Mild Dementia, Alzheimer's Disease
- Trial name
- NCT07027072
- Testing
- KDS2010
- Where
- 8 sites in South Korea
- Volunteers
- 114 people
- Sponsor
- NeuroBiogen Co., Ltd
Post-traumatic Stress Disorder
Evaluation of Desensitization Therapy and Re-treatment of Eye Movement Information [EMDR] in Patients With Post-traumatic Stress Disorder [PTSD]
This research aims to confirm that the therapeutic effect of EMDR is associated with changes in the interaction between cognitive function and emotional stimuli in PTSD patients compared to a controlled therapy in a randomized…
- Trial name
- ICE-EMDR (NCT04431765)
- Testing
- Eye Movement Desensitization Reprocessing therapy, Trauma-Centred Cognitive and Behavioural Therapy
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Dizziness, Vertigo
Assessment and Treatment of Patients With Long-term Dizziness in Primary Care
Brief Summary: The purpose of the present study is to examine the effects of a Group based intervention consisting of vestibular rehabilitation (VR) combined with cognitive behavioral therapy (CBT) in patients with long--lasting…
- Conditions
- Dizziness, Vertigo, Vestibular Neuritis
- Trial name
- LODIP (NCT02655575)
- Testing
- BI + VR + CBT, BI + phone calls
- Where
- Norway
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Bergen University College