Clinical trials: Cognitive Dysfunction, open to volunteers
Subarachnoid Aneurysm Hemorrhage
Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Despite its lower incidence rate within the stroke population and tendency to affect younger individuals, SAH carries the highest risk of PSCI.
- Trial name
- NCT07588997
- Testing
- early motor-cognitive integrated training (e-MCIT), Early mobilization
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Cognitive Dysfunction
The Application of an AI-driven Multimodal Predictive Model for Cognitive Impairment in Patients With Type 2 Diabetes Mellitus
The objective of this observational study is to evaluate the accuracy and feasibility of an artificial intelligence-based multimodal cognitive screening system in early identification of diabetes-related mild cognitive impairment…
- Trial name
- NCT07128186
- Testing
- follow-up observation
- Where
- 21 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Infectious Disease, Cardiovascular Diseases
Metabolic and Infectious Diseases in La Réunion (the REUNION Population-based Study)
The aim of the present study is to determine the prevalence of cardiometabolic and infectious disease in La Reunion (french oversea department and region of France).
- Conditions
- Infectious Disease, Cardiovascular Diseases, General Population, Metabolic Disease
- Trial name
- NCT05400824
- Testing
- Blood, DNA, feces, urine, hair and skin microbiota collection
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Cognitive Disorder
Virtual Reality Training for Inhibitory Control in Neurocognitive Disorders
Executive function disorders, such as inhibitory control (IC) difficulties, are very common in older adults with neurocognitive disorders (NCD).
- Trial name
- VR4IC (NCT06597591)
- Testing
- VR headset, Tablet
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Alzheimer Dementia (AD), Mild Cognitive Impairment (MCI)
Making Antibody Treatments More Effective in Early Alzheimer's Disease Using 3Tesla Magnetica Resonance
Alzheimer's disease causes progressive memory and cognitive decline, driven in part by the buildup of a protein called β-amyloid in the brain.
- Trial name
- NCT07456462
- Testing
- MRI assessment and blood sample collection
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Rehabilitation, Multiple Sclerosis
Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation
The first aim of this project is to investigate the effects of different high-tech neurorehabilitation interventions (cognitive, motor, and combined cognitive-motor) on both cognitive and motor disability outcomes in people with…
- Conditions
- Rehabilitation, Multiple Sclerosis, Cognitive Deficit, Motor Deficits
- Trial name
- NCT06820125
- Testing
- Cognitive rehabilitation: CG group, Motor rehabilitation: MG group, Combined rehabilitation: CbG group
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Universita di Verona
Cerebrovascular Disorders
Daphnetin Capsule In the Treatment of VaScular COgnitive Impairment Without Dementia
The purpose of this clinical trial is to understand and evaluate the clinical efficacy and safety of Daphnetin Capsule in patients with vascular cognitive impairment.
- Trial name
- DISCO (NCT06507488)
- Testing
- Daphnetin Capsule
- Where
- China
- Volunteers
- 206 people
- Sponsor
- First People's Hospital of Shenyang
Subjective Cognitive Complaints, Ehlers-Danlos Syndrome
COG+OT Telerehabilitation for Adults With Subjective Cognitive Complaints
This pilot study will evaluate a comprehensive cognitive assessment approach and personalized neurocognitive telerehabilitation intervention for adults with subjective cognitive complaints (SCC).
- Conditions
- Subjective Cognitive Complaints, Ehlers-Danlos Syndrome, Cognitive Dysfunction
- Trial name
- CogSCC (NCT07743229)
- Testing
- COG+OT Telerehabilitation
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline), Pain
Effect of Acupuncture on Psychoneurological Symptom Cluster in Breast Cancer Survivors
This clinical trial aims to assess whether electroacupuncture (EA) can alleviate the psychoneurological symptom cluster (including pain, fatigue, insomnia, anxiety, depression and subjective cognitive decline) in breast cancer…
- Conditions
- Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline), Pain, Insomnia, Anxiety
- Trial name
- NCT07481903
- Testing
- electroacupuncture
- Where
- 6 sites in China
- Volunteers
- 228 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Mild-moderate Cognitive Impairment
Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments
The goal of this clinical trial is to test a twice a week, moderate intensity exercise and coaching program (an in-person group and a distance group) for adults with mild-moderate cognitive impairments living in South Carolina.
- Trial name
- NCT06799429
- Testing
- Supervised Exercise and Behavior Modification Support, Monitored Exercise and Behavioral Modification Support
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of South Carolina
Temporomandibular Disorder, Temporomandibular Joint Disorders
Cognitive Exercise Therapy Approach Biopsychosocial Questionnaire (BETY-BQ) in Patient with Temporomandibular Disorders
The aim of this study is to investigate the validity, reliability, and responsiveness of the Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (BETY-BQ) in individuals with temporomandibular disorder.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
- Trial name
- NCT06186830
- Testing
- Validity and reliability analyses
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hacettepe University
Hemodialysis
Virtual Reality for Cognitive Impairment in Hemodialysis
The goal of this randomized feasibility clinical trial is to identify participant recruitment and retention, acceptability, and adherence to virtual reality training in people undergoing hemodialysis.
- Trial name
- VIRTUAL (NCT06739187)
- Testing
- Virtual reality platform on head mounted display
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- University of Campania Luigi Vanvitelli
Alzheimer Disease, Subjective Cognitive Decline
dTMS for Subjective Cognitive Decline
Deep transcranial magnetic stimulation (dTMS) is a brain stimulation technique that involves generating a brief magnetic field in a coil that is placed on the scalp.
- Trial name
- NCT06095063
- Testing
- Active Brainsway H7-Coil Deep TMS System, Cognitive Training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Rotman Research Institute at Baycrest
Alzheimer Disease, Mild Cognitive Impairment
Blood Tests for Alzheimer's Disease: Can Plasma Biomarkers Diagnose and Predict Disease Progression
BLAD is a prospective, monocentric, observational epidemiological study with an additional procedure (annual blood draw) evaluating the diagnostic and prognostic performance of plasma biomarkers for Alzheimer's disease (AD) in a…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Subjective Cognitive Decline, Dementia
- Trial name
- BLAD (NCT07717567)
- Testing
- Annual blood draw for plasma biomarker measurement
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Prodromal Alzheimer's Disease, Mild Cognitive Impairment
The Digital Memory Notebook
Compensatory aids (e.g., alarms, calendars) play an important supporting role when completing everyday tasks (e.g., appointments, medication management), and there is a growing body of scientific work suggesting that compensatory…
- Conditions
- Prodromal Alzheimer's Disease, Mild Cognitive Impairment, Subjective Cognitive Complaints
- Trial name
- DMN (NCT04240665)
- Testing
- Digital Memory Notebook (DMN) Application
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Negative Symptoms in Schizophrenia, Cognition Function
tACS to Improve Negative Symptoms & Cognition in Long-term Hospitalized Schizophrenia Patients.
This study aims to evaluate the efficacy of transcranial alternating current stimulation (tACS) on negative symptoms and cognitive function in long-term hospitalized patients with schizophrenia.
- Trial name
- NCT07074704
- Testing
- Hi-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tongji University
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Mild Cognitive Impairment
GAMES Intervention in MCI (Mild Cognitive Impairment)
The objective of the present study is to evaluate whether online, remote gameplay can facilitate social engagement and reduce feelings of loneliness and isolation in adults with and without mild cognitive impairment (MCI).
- Trial name
- NCT07296133
- Testing
- Online Gameplay Intervention, Waitlist control
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Emory University
Delirium, Dementia
Delirium and Cognitive Impairment Development in Hospitalized Older Adults Under Isolation Conditions
The goal of this observational study is to examine if older patients who need to be under isolation precautions due to multidrug resistant bacteria or other reasons have an increased risk of suffering from delirium or cognitive…
- Conditions
- Delirium, Dementia, Cognitive Impairment
- Trial name
- DELiso (NCT07114458)
- Where
- Germany
- Volunteers
- 404 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Breast Cancer, Sarcoma
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
This is a phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels in cancer survivors (recently…
- Conditions
- Breast Cancer, Sarcoma, Gastric Cancer, Lung Cancer
- Trial name
- NCT06580002
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Irvine
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.