Clinical trials: Cognitive Function Assessment
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Stress, Cognitive Impairment
Mindfulness-Based Health Promotion Program for Educators (MBHP - Educa).
In the last few decades, the world has seen a significant increase in the occurrence of occupational diseases related to Burnout Syndrome (professional exhaustion) and stress in educators.
- Conditions
- Stress, Cognitive Impairment, Burnout Syndrome
- Trial name
- Mindfulness (NCT03839030)
- Testing
- MBHP-Educa
- Where
- Brazil
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Marcelo Demarzo, MD, PhD
Breast Cancer, Breast Neoplasms
Mental and Cognitive Health and Physical Activity in the Perioperative Breast Cancer Setting
This study evaluates the complex relationships between mental health, cognitive function, and physical activity before surgery in patients with stage I-III breast cancer.
- Conditions
- Breast Cancer, Breast Neoplasms, Cancer, Breast, Cancer of the Breast
- Trial name
- NCT06595901
- Testing
- Actigraph, Questionnaires, BrainBaseline application
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
No Disease or Condition is Being Studied, The Aim: to Determine the Impact of a 25-minute Nap on Cognitive Function
The Effect of a Nap Protocol on the Cognitive Abilities of Experienced Teachers
This protocol aims to investigate the effects of a 25-minute nap on various cognitive variables, such as, simple and selective reaction time, stress and the detection and management of disruptive behaviors during instructional…
- Trial name
- NCT07655167
- Testing
- the nap routine
- Where
- Tunisia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Higher Institute of Sport and Physical Education, Ksar-Said
Brain Tumor
Assessment of Cognitive Functions and Quality of Life in Patients Undergoing Surgery for Supratentorial Brain Tumor
Primary brain tumors are highly associated with neurocognitive deficit and poor quality of life. There are number of studies indicating that brain tumors and their treatment modalities are often related to cognitive dysfunction.
- Trial name
- NCT02428972
- Testing
- Propofol, Sevoflurane
- Volunteers
- 30 people
- Sponsor
- All India Institute of Medical Sciences
Dementia, Mild Cognitive Impairment
Case-Finding for Neurocognitive Disorders in Pavia
Dementia is a global public health challenge with a heavy caregiving burden, impacting families, communities, and healthcare systems. It is a priority in healthcare planning, with focus on early diagnosis and ongoing support.
- Trial name
- C-FiND Pavia (NCT06983119)
- Testing
- Case-finding for Neurocognitive Disorders
- Where
- Italy
- Volunteers
- 490 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Learning Disorders, Depression
Move and Feel Good : Effects of Intensive Physical Training on Brain Plasticity, Cognition and Psychological Well-being.
The investigators perform a prospective, randomized, clinical study involving students in education with mood disorders and randomized to an intensive exercise program or a control relaxation activity.
- Conditions
- Learning Disorders, Depression, Anxiety
- Trial name
- Move&FG (NCT02970825)
- Testing
- Exercise, Relaxation
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Alzheimer's Disease
Risk Evaluation and Education for Alzheimer's Disease
The purpose of this study is to determine the characteristics of those who obtain genetic susceptibility testing for Alzheimer's disease with APOE disclosure and to study the psychological and behavioral consequences of providing…
- Trial name
- REVEAL I (NCT00571025)
- Testing
- APOE Disclosure
- Where
- 3 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cognitive Disorders
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-D4010 in Healthy Subjects
The purpose of this study is to investigate the safety, tolerability and pharmacokinetics of SUVN-D4010 in healthy male subjects following single or multiple ascending doses.
- Trial name
- NCT02575482
- Testing
- SUVN-D4010
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Suven Life Sciences Limited
Cognitive Function
Efficacy and Safety of Catechin High Contain Greentea Extract on Improvement of Cognitive Function
This study was the efficacy and safety of Catechin high contain greentea extract on improvement of Cognitive Function
- Trial name
- NCT03826017
- Testing
- Catechin high contain greentea extract
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Schizophrenia
Effect on Cognitive Function of a Treatment With Aripiprazole
To evaluate the effectiveness of Aripiprazole after 12 weeks of therapy for Schizophrenic patients.
- Trial name
- NCT00329810
- Testing
- Aripiprazole
- Volunteers
- 500 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Cognition Disorders in Old Age, Cognitive and Behavioral Impairment
Evaluation of the Effect of L-Arginine on the Cognitive Function in Geriatric Patients
This study aims to evaluate the effect of L-arginine supplementation on cognitive function in geriatric patients. Eligible participants will receive either L-arginine (6 grams once daily) or placebo, and their cognitive…
- Trial name
- NCT07338682
- Testing
- L-Arginine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- German University in Cairo
Mild Cognitive Impairment
Management of Mild Cognitive Impairment Patients With Extra Virgin Olive Oil - MICOIL
There is accumulating evidence suggesting that olive oil may have a positive impact on conditions involving cognitive deficits, such as MCI and AD.
- Trial name
- MICOIL (NCT03362996)
- Testing
- Freshly-Pressed Extra Virgin Olive Oil, extra virgin olive oil, mediterranean diet
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Greek Alzheimer's Association and Related Disorders
Alzheimer Disease, Physical Activity
Inspiring Seniors Towards Exercise Promotion to Protect Cognition
The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints.
- Trial name
- iSTEP+ (NCT06496425)
- Testing
- Beat-accentuated, personalized music stimulation (BMS), Strength Training (ST), Aerobic exercise (AE)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emory University
Delirium, Depression
Incidence and Predictors of Delirium After Cardiac Surgery
The objective of the present research is to evaluate the incidence and independent predictors of delirium observed among patients after cardiac surgery.
- Conditions
- Delirium, Depression, Cognitive Impairment
- Trial name
- IPDACS (NCT00784576)
- Where
- Poland
- Volunteers
- 563 people
- Sponsor
- Medical University of Lodz
Academic Acheivement, Physical Activity
Effects of Physical Activity on Math - an RCT
Background Increased physical activity can improve cognition and academic skills. However due to economic concerns and increasing focus on standardized testing, PA in schools often receives little attention and physical education…
- Trial name
- NCT02488460
- Testing
- Physically active math lessons
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Healthy Volunteers (HV)
Examining the Effects of Reformer Pilates Exercises on Physical Fitness and Cognitive Functions in Healthy Individuals
Pilates is an exercise method that aims to increase body awareness and improve physical fitness through controlled movements based on mind-body integration.
- Trial name
- NCT07134517
- Testing
- Pilates exercise
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Inonu University
Iron-deficiency, Iron Deficiency Anemia
Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Colorectal Cancer, Fatigue
- Trial name
- NCT04749589
- Testing
- iron deficiency
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Aging
Effects of Two Types of Concurrent Training in Functional Performance and Cognitive Function of Older Adults
The goal of this randomized controlled clinical trial is to identify and compare the impacts of traditional concurrent training and concurrent training consisting of strength training combined with dance classes on functional…
- Trial name
- NCT05859243
- Testing
- Traditional concurrent training, Concurrent training consisting of strength training combined with dance classes
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eduardo Lusa Cadore
Cognitive Impairment, Predictive Model
Risk Prediction and Its Intelligent Assessment for Cognitive Impairment Among Community-dwelling Older Adults
Cognitive impairment is one of the core early signs of dementia, and it is also a key stage for community-based dementia prevention.
- Conditions
- Cognitive Impairment, Predictive Model, Aging, Cohort
- Trial name
- NCT05385874
- Where
- China
- Volunteers
- 13,228 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital