Clinical trials: Cognitive Function and Mental Health
Mild Cognitive Impairment (MCI)
Feasibility Study of 'SuperBrain BOOM' for Mild Cognitive Impairment Patients
The goal of this clinical trial is to learn whether a mobile-based personalized physical activity program called SuperBrain BOOM is safe and works to improve cognitive function, physical performance, mood, and quality of life in…
- Trial name
- SuperBrainBOOM (NCT07101380)
- Testing
- Tablet-based Physical SuperBrain BOOM, Smartphone-based SuperBrain BOOM
- Where
- 4 sites in South Korea
- Volunteers
- 45 people
- Sponsor
- Ajou University School of Medicine
Knowledge Translation, Cognitive Impairment
Preventing and Managing Cognitive Impairment
This randomized controlled trial (RCT) is used to address the knowledge translation of primary care practitioners (PCPs) for the early identification of cognitive impairment.
- Trial name
- CognitnECHO (NCT05471141)
- Testing
- Cognition ECHO
- Sponsor
- Charles Drew University of Medicine and Science
Insomnia, Physical Health Functioning
Efficacy of a Computerized Cognitive Behavioral Treatment for Insomnia: Increasing Access to Insomnia Treatment to Decrease Suicide Risk
Insomnia is major problem among Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), and Operation New Dawn (OND) Veterans.
- Conditions
- Insomnia, Physical Health Functioning, Mental Health Functioning
- Trial name
- Vets Sleep (NCT03366870)
- Testing
- Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alzheimer Disease
Effects of a Cognitive-Engaging Strength Training Program on Health, Physical Condition, and Quality of Life in People With Alzheimer's Disease
The primary objective of this project is to examine the impact of a strength training program with high cognitive demands on cognitive function, motor skills, physical fitness, and quality of life in individuals with Alzheimer's…
- Trial name
- NCT07022431
- Testing
- Interval strength training
- Volunteers
- 34 people
- Sponsor
- University of Seville
Virtual Reality, Cognitive Impairment
Virtual Reality Training Intervention on Cognitive Function and Quality of Life
The present study aimed to investigate the effects of a Virtual Reality cognitive training intervention (VRCTI) on cognitive function changes measured with a cognitive test battery and improvement of quality of life in older…
- Conditions
- Virtual Reality, Cognitive Impairment, Quality of Life
- Trial name
- NCT05329272
- Testing
- Virtual Reality Cognitive Training Intervention (VRCTI)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- I-Shou University
Alzheimer's Disease (AD)
Cognitive Health in Ageing Register: Investigational and Observational Trial Studies in Dementia Research (CHARIOT): Prospective Readiness Cohort (PRO) Longitudinal Study
Alzheimer's disease is a degenerative condition affecting the brain and is the most frequent form of dementia in older adults. Dementia is currently a major healthcare issue in the UK, affecting approximately a million people.
- Trial name
- CPLS (NCT06953167)
- Where
- United Kingdom
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Depressive Symptoms
Cognitive Stimulation Program With Virtual Reality for Older Adults With Depressive Symptoms
The aim of this pilot RCT is the development, implementation, and evaluation of a cognitive stimulation program with virtual reality for individuals aged 65 or older who have depressive symptoms and attend Portuguese day centers.
- Trial name
- NCT07710222
- Testing
- Cognitive stimulation program
- Volunteers
- 60 people
- Sponsor
- Grupo Lusófona
Mild Cognitive Impairment (MCI), Older Adults With Cognitive Decline
Wearable Sensor for Early Detection and Monitoring of Cognitive Decline
This observational study will enroll approximately 100 participants evenly split by cognitive status (Cognitively Impaired vs Non-Cognitively Impaired), and involves four clinic visits over one year (at baseline, 3, 6, and 12…
- Conditions
- Mild Cognitive Impairment (MCI), Older Adults With Cognitive Decline, Older Adults
- Trial name
- NCT07780162
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- BioSensics
Hypochondriasis, Somatoform Disorders
Comparing Cognitive Therapy and Exposure Therapy in Individuals With Hypochondriasis
This study will compare the efficacy of cognitive therapy and exposure therapy for treating hypochondriasis.
- Trial name
- NCT01119469
- Testing
- Psychotherapy (CT or ET)
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- Goethe University
Alzheimer Disease, Dementia
Technology and Family Thriving Study
The purpose of this project is to test the impact of different forms of technology (virtual reality vs. video chat) on quality of life and family relationships in older adults who reside in senior living communities and an adult…
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life
- Trial name
- Thrive (NCT05150990)
- Testing
- Virtual Reality, Video Chat
- Where
- 27 sites in United States
- Volunteers
- 186 people
- Sponsor
- University of California, Santa Barbara
Bipolar Disorder
Cognitive-Behavior Therapy for Young Adults With Bipolar Disorder
The aim of the study is to develop and pilot test a cognitive-behavioral (CBT) intervention for young adults, ages 18-24 with bipolar disorder.
- Trial name
- NCT01176825
- Testing
- cognitive-behavior therapy (CBT)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Massachusetts General Hospital
Sleep, Cognitive Impairment
Observational Study About Sleep Quality and Its Impact on Daily Life of Nursing-home Residents
Introduction: Poor sleep quality is common in most older adults. Because of the progressive aging of the population in Spain, there are more and more nursing-home and day centers, which give care to older adults.
- Conditions
- Sleep, Cognitive Impairment, Quality of Life, Age Problem
- Trial name
- NCT04592796
- Testing
- Xiaomi MiBand2, Socio-demographic questionnaire, EuroQol-5D-5L
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Universidade da Coruña
Renal Insufficiency,Chronic, Dietary Intake Patterns
Strategies for Proactive Health in People With Kidney Function Decline
This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression.
- Conditions
- Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty
- Trial name
- NCT07245186
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Huashan Hospital
Cognitive Decline, Cognitive Deficit
Validation Study SCOBES-AR
Purpose of the study The purpose of this study is to evaluate five tests to see if they are suitable for the early detection of cognitive impairment in people over the age of 60.
- Conditions
- Cognitive Decline, Cognitive Deficit, Cognitive Impairment
- Trial name
- NCT04204239
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Suicidal Ideation, Depressive Disorder
Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy
Suicide is a national crisis, especially among older Veterans for whom evidence-based suicide prevention efforts are lacking. This proposal responds to the national priority to develop and improve interventions for suicide…
- Conditions
- Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder
- Trial name
- NCT04763330
- Testing
- Enhanced Usual Care (EUC), Problem Solving Therapy (PST) plus EUC
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- VA Office of Research and Development
Attention Disorder
Analysis of the Impact of a Temporo-spatial Reorientation Tool on the Speed of Improvement of Confusional Syndrome
Confusion syndrome is defined by attentional disorders and disorganization of cognitive functions that are acute and reversible. There are patient-specific predisposing factors and precipitating factors.
- Trial name
- Rob'Gazette (NCT06498297)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Cognitive Dysfunction
Immersive Nature-Based Wellbeing Program in Older Adults With Cognitive Impairment
This study aims to evaluate an immersive virtual reality program designed to support cognitive and emotional well-being in older adults with mild to moderate cognitive impairment.
- Trial name
- COGNITIO (NCT07802392)
- Testing
- Immersive virtual reality program
- Where
- Spain
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Feasibility Studies, Physical Activity and Wellbeing
Physical Activity Intervention for Older Family Carers
The goal of this pilot trial is to learn whether a six-month physical activity program tailored for older family caregivers can be successfully delivered and whether participants are willing and able to take part in it.
- Trial name
- CAREFIT (NCT07653061)
- Testing
- Physical activity intervention for older family caregivers, Health education
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University
Wellness, Burnout
Effect of Sleep Deprivation on Cognitive Function Among Cardiology Fellows
A reliable method for monitoring sleep, stress, and burnout among cardiology fellows is critically needed. To address this gap, our team aims to utilize the cost-effective WHOOP strap 4.0 wearable device to continuously capture…
- Conditions
- Wellness, Burnout, Sleep Deprivation, Executive Function
- Trial name
- NCT05513339
- Testing
- WHOOP strap 4.0
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University