Clinical trials: Cognitive Function and Mental Health
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Dementia
Examining the Relationship Between Hormone Therapy (HT) and Cognitive Function (The WHIMS-ECHO Study)
This is a prospective, observational study of the cohort of older post-menopausal participants in the WHI Memory Study, a sub-cohort of participants in the WHI Hormone Trials.
- Trial name
- WHIMS-ECHO (NCT00745056)
- Where
- United States
- Volunteers
- 2,922 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Insomnia, Cognition
The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV
The goal of this clinical trial is to examine the effects of a telephone-delivered Brief Behavioral Treatment Insomnia (BBTI) versus a Brief Mindfulness Treatment (BMT) on cognitive and sleep outcomes in older adults with HIV.
- Conditions
- Insomnia, Cognition, Aging, HIV
- Trial name
- NCT07272863
- Testing
- BBTI, BMT
- Where
- 2 sites in United States
- Volunteers
- 214 people
- Sponsor
- University of Alabama, Tuscaloosa
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life
This study evaluates the feasibility and efficacy of the Samphire Guided Care (SGC) program a 12-week structured digital health program combining clinician-led onboarding, at-home neuromodulation using the Lutea tDCS device…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Dysmenorrhea, Endometriosis
- Trial name
- CREST (NCT07679074)
- Testing
- Lutea Transcranial Direct Current Stimulation (tDCS) Device, Samphire Guided Care Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samphire Group, Inc.
Frail Elderly, Cognitive Impairment
A Community Health Worker Program to Support Rural Older Adults
This study will investigate an intervention delivered by community health workers for older adults with signs of cognitive impairment, mobility loss, and depression in the rural primary care setting.
- Conditions
- Frail Elderly, Cognitive Impairment, Mobility Limitation, Depressive Symptoms
- Trial name
- NCT03843333
- Testing
- Tai Ji Quan: Moving for Better Balance, Behavioral Activation, Resource Navigation
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of Vermont
Mild Cognitive Impairment
A Health Game Intervention for Cancer and Post-ICU Patients Suffering From Acute Cognitive Impairment
Millions of patients each year suffer from acute cognitive impairment caused by traumatic brain injury, stroke, Parkinson's disease, etc.
- Trial name
- NCT07596940
- Testing
- VR cognitive training platform
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Cincinnati
Cognitive Function
Radicle Clarity DSTTM: A Study Assessing the Impact of Health and Wellness Products on Mental Clarity and Related Health Outcomes
Radicle Clarity DSTTM: A randomized, double-blind, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on mental clarity and related health outcomes.
- Trial name
- NCT07342192
- Testing
- RS Clarity Active Product
- Where
- United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Bipolar Disorder
Clinical Determinants of the Discrepancy Between Objective and Subjective Cognition in the Versailles FACE-BD Cohort
Metacognitive abilities have been scarcely investigated in bipolar disorders, with inconsistent results. This may appear somewhat surprising, as metacognitive training is a very promising intervention aiming at improving…
- Trial name
- METACOG-BD (NCT04034147)
- Where
- France
- Volunteers
- 387 people
- Sponsor
- Versailles Hospital
Schizophrenia, Substance Use
Effects of Physical Activity in Psychosis
Physical health problems are common in schizophrenia with a two- to three-fold increased morbidity and mortality rate, resulting in a 20 years reduction in life expectancy.
- Trial name
- EPHAPS (NCT02205684)
- Testing
- Computer game skills training, Physical activity
- Volunteers
- 126 people
- Sponsor
- Sykehuset i Vestfold HF
Chronic Kidney Diseases
Effects of Prebiotic Supplementation and Exercise on Inflammatory Markers, Vascular Function and Cognition in CKD
The study is primarily designed to examine the effect of 16 weeks of prebiotic supplementation (resistant starch)and moderate intensity aerobic training on markers of inflammation in stage 3-4 patients with chronic kidney disease.
- Trial name
- NCT03689569
- Testing
- Resistant starch, Exercise, Starch
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Springfield College
Inflammation, Cognitive Impairment
Trial Assessing Light Intensity Exercise on the Health of Older Breast Cancer Survivors
The Trial Assessing Light-Intensity Exercise on the Health of Older Breast Cancer Survivors pilot randomized controlled trial aims to evaluate the efficacy of a home-based, light-intensity physical activity intervention among 56…
- Conditions
- Inflammation, Cognitive Impairment, Anxiety, Alcohol Drinking
- Trial name
- TALIEHO (NCT04965246)
- Testing
- Physical Activity, Usual Care
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Milton S. Hershey Medical Center
Huntington Disease
Family Health After Predictive Huntington Disease (HD) Testing
The purpose of this study is to identify health management concerns and needs of family members of asymptomatic and symptomatic persons with mutation in the gene for Huntington Disease (HD).
- Trial name
- NCT00075140
- Testing
- Mutation in the gene
- Where
- United States
- Volunteers
- 422 people
- Sponsor
- National Institute of Nursing Research (NINR)
Cognitive Dysfunction, Subjective Health
Effectiveness of TeleVR App in Cognitive Decline and MCI Patients
The goal of this clinical trial is to evaluate the effectiveness of a telerehabilitation program combined with a virtual reality (VR) app in improving cognitive performance and social skills in patients with Subjective Cognitive…
- Conditions
- Cognitive Dysfunction, Subjective Health, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- TeleVR24 (NCT06793735)
- Testing
- Telerehabilitation with Virtual Reality, Traditional Cognitive Rehabilitation
- Where
- Italy
- Volunteers
- 480 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Cognitive Impairment
Evaluation of the Effect of Cooled Haemodialysis on Cognitive Function in Patients Suffering With End-stage KD
The Investigators aim to perform a feasibility study that will inform the development of a definitive, fully powered, randomised, controlled clinical trial in the future.
- Trial name
- E-CHECKED (NCT03645733)
- Testing
- Lower Temperature Group
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Heart of England NHS Trust
Relatives, Health Care Providers
A Complex Intervention Study on a Palliative Rehabilitation Blended Learning Program to Support Relatives and Health Care Providers of People With ALS and Cognitive Impairments in Coping With Challenges
A complex intervention study on a palliative rehabilitation blended learning program to support relatives and health care providers of people with ALS and cognitive impairments in coping with challenges.
- Conditions
- Relatives, Health Care Providers, Cognitive Impairment, Rehabilitation
- Trial name
- NCT04638608
- Testing
- EMBRACE (relatives), EMBRACE (Health care providers)
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Danish Rehabilitation Centre for Neuromuscular Diseases
Critical Illness, COVID-19
A Study of Healthy Microbiome, Healthy Mind
Researchers are doing this study to find out if a high fermented food diet is tolerable, and if it will help improve quality of life after surviving a critical illness, including severe COVID-19, by promoting gut health recovery…
- Conditions
- Critical Illness, COVID-19, PICS, Cognitive Impairment
- Trial name
- NCT06020703
- Testing
- Fermented Food Diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Cognitive Decline, Age-Related Memory Disorders
Prehabilitation Exercise Plus Perioperative Optimization of Senior Health
The purpose of this study is the examine the feasibility of and estimate the efficacy of a preoperative exercise (i.e. prehabilitation) program in 40 up to sedentary older adults (i.e.
- Conditions
- Cognitive Decline, Age-Related Memory Disorders, Postoperative Complications, Age-Related Atrophy
- Trial name
- NCT03291795
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Duke University
Low Skeletal Muscle Mas
High- and Moderate-Intensity Inspiratory Muscle Training on Diaphragm Ultrasound Parameters, Cognition, and Mental Health
Low skeletal muscle mass during young adulthood may impair diaphragm function, cognition, sleep, and psychological well-being. Inspiratory muscle training (IMT) has been shown to improve respiratory muscle performance; however…
- Trial name
- NCT07757139
- Testing
- High-Intensity IMT, Moderate-Intensity IMT
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Cognitive/Functional Effects, Depression
Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer
RATIONALE: Gathering information from older patients with newly diagnosed cancer may help doctors learn more about the risks of functional decline.
- Conditions
- Cognitive/Functional Effects, Depression, Hematopoietic/Lymphoid Cancer, Malnutrition
- Trial name
- NCT00769951
- Testing
- medical chart review, questionnaire administration, cognitive assessment
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Case Comprehensive Cancer Center