Clinical trials: Cognitive Functioning, open to volunteers
COPD, Physical Activity
Effects of Adapted Snacktivity™ Intervention on Cognition and Self-Care in COPD Patients
This clinical trial aims to evaluate whether a culturally adapted Snacktivity™ program can improve cognitive function and self-care abilities in patients with Chronic Obstructive Pulmonary Disease (COPD) in Hong Kong.
- Conditions
- COPD, Physical Activity, Cognition, Self Care
- Trial name
- Snacktivity™ (NCT07702994)
- Testing
- Snacktivity™ Intervention, attention control
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Post-Stroke Cognitive Impairment (PSCI), Stroke
Artificial Intelligence-Based Cognitive Training in Patients With Stroke
This study would answer the following question:Does AI application-based training improve cognitive function in Patients with Stroke? The aims of this study: To investigate the efficacy of AI application-based training on…
- Conditions
- Post-Stroke Cognitive Impairment (PSCI), Stroke, Artifical Intelligence
- Trial name
- AICoRe-Stroke (NCT07452276)
- Testing
- cognifit Mobile Application for Cognitive Training, Conventional Cognitive Rehabilitation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Omima Alaa Eldin Hussein
Cervical Radiculopathy, Forward Head Posture
Correlation Between Forward Head Posture and Executive Functions in Cervical Radiculopathy
PURPOSE: This study aims to: Investigate the relationship between Forward Head Posture (FHP), Pain Intensity and executive functions in patients with Cervical Radiculopathy (CR).
- Trial name
- NCT07906847
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Cognitive Decline, Dementia Prevention
Small Monetary Incentives for Digital Cognitive Training Adherence in Community-Dwelling Older Adults
This study aims to find out whether small daily monetary rewards can help older adults living in the community to regularly complete digital cognitive training.
- Trial name
- NCT07913243
- Testing
- Digital cognitive training, Monetary incentive 0.2 CNY/day, Monetary incentive 0.5 CNY/day
- Where
- 5 sites in China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Aging
Breaking Sitting with High-intensity Interval Training for Brain Health
This trial will examine whether interrupting 3.5 hours of sitting every 30 min with 6 min high intensity interval training (HIIT) breaks compared to light intensity interval training (LIIT) will improve brain health in…
- Trial name
- HIIT2SITLess (NCT06243016)
- Testing
- High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
PARKINSON DISEASE (Disorder), Parkinson s Disease
Effects of Accelerated rTMS On Motor and Cognitive Function in Parkinson's Disease
Parkinson's disease (PD) is a brain disorder that causes progressive problems with movement, such as slowness, stiffness, tremor, and difficulty walking. Many people with PD also develop problems with thinking and memory.
- Trial name
- NCT07554833
- Testing
- TMS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- San Francisco Neurology and Sleep Center
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Mild Cognitive Impairment (MCI)
Cognitive-Frailty Gait Biomechanics for Early Dementia Detection
The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults.
- Trial name
- gait dementia (NCT07448909)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Screen-use Reduction + Sleep Extension, Free-living
Personalising Children's Screen Use Reduction for Better Sleep, Mental, and Brain Health
In Singapore, 64.4% of school-age children sleep less than the minimum recommended duration of 9 hours on school nights, thus risking poor mental, cognitive, and brain health.
- Trial name
- NCT05956392
- Testing
- Screen-use reduction + Sleep extension
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Older Adults (65 Years and Older), Cognition
Effects of Breathing Exercises on Cognition in Older Adults
The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older.
- Conditions
- Older Adults (65 Years and Older), Cognition, Balance Control in Elderly, Fall Prevention in Healthy Aging
- Trial name
- NCT07505914
- Testing
- Balance Training Program, Inspiratory Muscle Training, Breathing Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Alzheimer Disease (AD)
Intravenous Infusion of Umbilical Cord Blood as an Adjunctive Treatment for Alzheimer's Disease
This study is a single-center, prospective, double-blind, randomized controlled clinical trial (RCT). Employing a parallel-group design, the trial plans to enroll 30 clinically diagnosed AD patients, who will be randomly assigned…
- Trial name
- NCT07208344
- Testing
- Intravenous infusion of mononuclear cells from umbilical cord blood, Conventional medical treatment：donepezil, rivastigmine or galantamine
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Anhui Provincial Hospital
Alzheimer s Disease
Deep Cervical Lymphovenous Anastomosis for Severe Alzheimer's Disease
Alzheimer's disease (AD) is a severe neurodegenerative disease with heavy social burden. Current drugs cannot reverse disease progression.
- Trial name
- DCLVA-AD (NCT07669272)
- Testing
- Deep Cervical Lymphovenous Anastomosis, Routine Treatment
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Southwest Hospital, China
Hypertension, Condition
Adaptive Cognitive Training on Cognitive Function in Elderly Hypertension Patients in the Community
Objective A growing body of evidence supports hypertension as a risk factor for cognitive decline. Hypertension is significantly associated with accelerated cognitive decline, poorer cognitive function, and mild cognitive…
- Conditions
- Hypertension, Condition, Aging
- Trial name
- NCT06512922
- Testing
- adaptive cognitive training
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Mental Health Wellness, Cognitive Function
Children to Adults Mental and Psychosomatic Health Study (CAMPS)
This study titled the Children to Adults Mental and Psychosomatic Health Study (CAMPS), aims to explore the interplay between mental health, psychosomatic factors, and adverse childhood experiences (ACE) across a broad age range…
- Conditions
- Mental Health Wellness, Cognitive Function, Physical Symptoms
- Trial name
- NCT05621278
- Where
- China
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Irritable Bowel Syndrome, Abdominal Pain
Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children
The goal of this clinical trial is to test efficacy of the REACH program in parents with irritable bowel syndrome (IBS) and their young children.
- Trial name
- REACH (NCT05730491)
- Testing
- Social Learning and Cognitive Behavioral Therapy (SLCBT), Attention Education Control
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Seattle Children's Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Cognitive-Motor Training With the DextEgg in Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) is frequently accompanied by deficits in executive functions and fine motor skills, which affect daily activities, academic performance, and health-related quality of life.
- Trial name
- ADHD DextEgg (NCT07913997)
- Testing
- Cognitive-motor DextEgg training, Motor-only DextEgg training
- Volunteers
- 50 people
- Sponsor
- Manuela Pastore-Wapp
Cognitive Training, Functional Core Stability Training
Effect of Functional Core Stability Training or Cognitive Training on Balance and Postural Control in Chronic Ankle Instability
The purpose of the study is to investigate dynamic core stability training versus cognitive training on balance, functional performance, postural control, ankle instability scores, ankle dorsiflexion range of motion, and mental…
- Conditions
- Cognitive Training, Functional Core Stability Training, Balance; Distorted, Postural Control
- Trial name
- NCT07283276
- Testing
- strengthening exercises, Balance training, Functional core training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Postoperative Cognitive Dysfunction (POCD), Cognitive Change
Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty
The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery.
- Conditions
- Postoperative Cognitive Dysfunction (POCD), Cognitive Change, Total Knee Arthroplasty, Unicompartmental Knee Arthroplasty
- Trial name
- NCT07598552
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Odense University Hospital
Traumatic Brain Injury, Cognitive Decline
Cognitive and Vascular Functioning Following TBI
This observational study will examine the association of chronic traumatic cerebrovascular injury and cardiovascular risk factors with TBI-related cognitive impairment and vascular dementia.
- Conditions
- Traumatic Brain Injury, Cognitive Decline, Vascular Dementia
- Trial name
- NCT06034509
- Testing
- No intervention. This is an observational study.
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Walter Reed National Military Medical Center
Alzheimers Disease, Mild Cognitive Impairment
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor…
- Trial name
- NCT06484244
- Testing
- 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University