Clinical trials: Cognitive Functions, open to volunteers
Dementia; Degenerative, Dementia Mixed
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday).
- Trial name
- tES (NCT06877312)
- Testing
- Transcranial Direct Current Stimulation (tDCS), 30 Hz Transcranial Alternating Current Stimulation (tACS), 50 Hz Transcranial Alternating Current Stimulation (tACS)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Cancer Related Cognitive Difficulties, Breast Cancer Female
Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI
Study is enrolling newly diagnosed breast cancer patients about to start chemotherapy and age-matched control participants. The investigator is trying to better understand the prevalence of cognitive difficulties in cancer…
- Trial name
- NCT03137095
- Testing
- Cognitive testing, Research Brain MRI
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Heart Failure With Preserved Ejection Fraction
EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)
The goal of this clinical trial is to learn if therapy with activin ligand-trap biological therapy (an investigational drug) combined with exercise training can improve exercise capacity and cognitive function in heart failure…
- Trial name
- EXAMINE-HFC (NCT07202000)
- Testing
- Activin ligand-trap biological therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Massachusetts General Hospital
High Intensity Interval Training, Heart Failure
Effects of Upper Extremity Low Volume HIIT in Heart Failure
This study was planned to investigate the effects of upper extremity low-volume high-intensity interval training (LV-HIIT) on physical and cognitive function in patients with heart failure with preserved ejection…
- Conditions
- High Intensity Interval Training, Heart Failure, Exercises
- Trial name
- NCT06754475
- Testing
- Low-volume, high-intensity interval training, Standart medical treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Tarsus University
Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment
Physiological Effect of Non-invasive Photobiomodulation on Cognition and Mood in Older Adults With Subjective Cognitive Impairment
Subjective cognitive impairment (SCI) is a non-clinical condition manifesting as a self-reported decline in cognitive function without objective clinical evidence, and is prevalent among older adults and strongly associated with…
- Trial name
- NCT07445945
- Testing
- Photobiomodulation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Baycrest
Non-acute Carotid Artery Occlusion, Cognitive Impairment
Endovascular Treatment for Symptomatic Non-acute Carotid Occlusion
This study is a multicenter, prospective, randomized, open-label, blinded-endpoint clinical trial designed to evaluate the safety and potential efficacy of endovascular recanalization strategies in patients with symptomatic…
- Trial name
- ASCENT (NCT07803419)
- Testing
- Guideline-Based Best Medical Treatment, Endovascular Recanalization With Proximal Balloon Protection, Endovascular Recanalization Without Proximal Protection
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Dapeng Mo
Brain Vascular Function, Cognitive Function
Effects of Protein Supplementation on Brain Function
Protein-rich foods may improve brain insulin-sensitivity, which is important for cognitive and metabolic health, and may also translate into an improved food intake regulation.
- Conditions
- Brain Vascular Function, Cognitive Function, Satiety, Cerebral Blood Flow
- Trial name
- NCT07057245
- Testing
- Protein supplementation with an animal-based protein isolate, Protein supplementation with a plant-based protein isolate, Control arm - cornstarch
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Breast Cancer, Sleep
Impact of Sleep Disturbance on Cognition and Quality of Life in Breast Cancer
Patients treated for breast cancer frequently complain of sleep disturbances, about 40% of them. Of the sleep disturbances experienced by patients, insomnia is the most common complaint.
- Conditions
- Breast Cancer, Sleep, Quality of Life
- Trial name
- ICANSLEEP (NCT05414357)
- Testing
- Functional Magnetic Resonance Imaging at rest and in activation with attentional task
- Where
- 2 sites in France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Mild Cognitive Impairment Due to Alzheimer's Disease, Subjective Cognitive Decline (SCD)
Autophagy-Enhancers to Reduce Sleep Disturbances
This clinical trial investigates the effects of spermidine supplementation on sleep quality and sleep-dependent memory consolidation in older adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI), two…
- Trial name
- SpSleep (NCT07383311)
- Testing
- Spermidine Supplementation
- Where
- Germany
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Depression
Benefits of Exergames on Neurocognitive Functions in Adults Suffering From Depression
The purpose of this study is to analyse the changes derived from exergames (videogames that include cognitive and physical stimulation simultaneously), in terms of cognitive functioning, psychomotor abilities, and its neural…
- Trial name
- MUDGAME (NCT06536530)
- Testing
- Exergame-Based Training, Cognitive-Based Training, Wait-List
- Volunteers
- 150 people
- Sponsor
- MAP Institute
Older Adults (65 Years and Older), Cognition
Effects of Breathing Exercises on Cognition in Older Adults
The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older.
- Conditions
- Older Adults (65 Years and Older), Cognition, Balance Control in Elderly, Fall Prevention in Healthy Aging
- Trial name
- NCT07505914
- Testing
- Balance Training Program, Inspiratory Muscle Training, Breathing Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Haemodialysis, Kidney Failure
Dialysate Cooling for the Preservation of Cognitive Function in People Receiving Haemodialysis
When a person's kidneys are not working properly, they need a life-saving treatment called haemodialysis three times a week to filter the waste and extra fluids from the blood.
- Trial name
- COOL HD (NCT07377500)
- Testing
- Dialysis cooling
- Where
- United Kingdom
- Volunteers
- 356 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Dementia (Diagnosis), Alzheimer Dementia (AD)
Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)
The goal of this observational study is to learn if an artificial intelligence (AI)-based speech analysis tool can identify which patients with memory problems need specialist evaluation at a memory clinic.
- Conditions
- Dementia (Diagnosis), Alzheimer Dementia (AD), Vascular Dementia (VaD), Lewy Body Dementia (LBD)
- Trial name
- DetectAI (NCT07200739)
- Testing
- Mini-mental State Examination, Addenbrooke's Cognitive Examination, Speech Task - Picture Description
- Where
- Denmark
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Frailty
Effect of an Exercise Program for Frail Older Adults
Despite the high level of evidence for physical activity as a countermeasure for frailty, the current Flemish standard of care does not include structural PA interventions for community-dwelling frail older adults.
- Trial name
- AA@HOME (NCT05946109)
- Testing
- ACTIVE-AGE@home
- Where
- Belgium
- Volunteers
- 195 people
- Sponsor
- Universitair Ziekenhuis Brussel
Vitamin D 25-Hydroxylase Deficiency, Vitamin D Deficiency/Insufficiency
Effects of High-Dose Vitamin D on Hormones, Neuromuscular Function, Cognition, and Body Composition in Athletes
This study aims to evaluate the effects of high-dose vitamin D3 supplementation on selected physiological, neuromuscular, and cognitive parameters in athletes.
- Trial name
- NCT07641075
- Testing
- Vitamin D supplementation
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Dementia, Mild Cognitive Impairment (MCI)
Combating Alzheimer's Through Sleep and Exercise
The Combating Alzheimer's through Sleep and Exercise (CASE) study is an exploratory, hypothesis-generating trial designed to: (1) assess whether improvements in sleep are associated with improvements in cognitive performance and…
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Alzheimer's Dementia (AD)
- Trial name
- CASE (NCT04855630)
- Testing
- Elemind Neuromodulation Headband, Exercise Routine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami
Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation
Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI
Provision of interventions that address cognitive and emotional problems faced by Veterans with history of TBI pursuing community reintegration is an important concern for VA.
- Conditions
- Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation, Veteran
- Trial name
- GOALS TH (NCT07190365)
- Testing
- GOALS TH, EDU TH
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, Randomized Controlled Trial
Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities
The aim of the study is to evaluate, at the level of global cognition, cognitive neuroconstructs, memory, verbal fluency, ADLs, IADLs, symptoms of depression and anxiety, the effectiveness of a personalised and adapted…
- Conditions
- Mild Cognitive Impairment, Randomized Controlled Trial, Subjective Cognitive Impairment
- Trial name
- NCT06058611
- Testing
- Cognitive stimulation, Stimulating leisure activities
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Spinal Cord Injury
Virtual Reality Dual Task Training in SCI: Effects on Cognition and Cortical Activation
Spinal cord injury (SCI) is a severe neurological condition characterized by the loss of motor and sensory functions due to damage in the spinal cord or the nerves branching from it.
- Trial name
- NCT07019207
- Testing
- VR-Based Dual-Task Training with Motor Imagery, VR-Based Dual-Task Training without Motor Imagery, Proprioceptive Neuromuscular Facilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istinye University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.