Clinical trials: Cognitive Health
Diabetes Mellitus, Type 1
Effectiveness of a Combined mHealth-CBT Psychological Intervention to Improve Psychological Well-Being in Young Patients With T1D
Type 1 diabetes (T1D) can lead to psychological adjustments that impact the acceptance and management of this health condition, as well as the overall quality of life of patients, especially among the young.
- Trial name
- NCT06450730
- Testing
- Cognitive-Behavioral Therapy: face-to-face + app
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Cancer Survivor, Insomnia
Yoga, Survivorship Health Education, and Cognitive Behavioral Therapy in Reducing Insomnia in Cancer Survivors
This randomized phase III trial compares yoga, survivorship health education program, and cognitive behavioral therapy in reducing sleep disturbance (insomnia) in cancer survivors.
- Conditions
- Cancer Survivor, Insomnia, Malignant Neoplasm
- Trial name
- YOCAS-II (NCT02613364)
- Testing
- Behavioral Intervention, Cognitive Intervention, Educational Intervention
- Where
- 16 sites in United States
- Volunteers
- 746 people
- Sponsor
- University of Rochester NCORP Research Base
Alzheimer Disease, Mild Cognitive Impairment
A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD)
The purpose of this study is to learn about health care use, costs, and clinical outcomes over time for amyloid positive participants with early stages of AD in the United States.
- Trial name
- GERAS-US (NCT02951598)
- Testing
- Florbetapir F 18 PET Scan
- Where
- 77 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- Eli Lilly and Company
Mild Cognitive Impairment, Aged
South Korean Study to Prevent Cognitive Impairment and Protect Brain Health Through Lifestyle Intervention
This study evaluates acceptability and efficacy of multidomain intervention program to prevent cognitive impairment and protect brain health in Korean at-risk elderly.
- Trial name
- SUPERBRAIN (NCT03980392)
- Testing
- Multidomain intervention program
- Where
- 6 sites in South Korea
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Noise Exposure, Sleep Disturbance
Effects of Railway Vibration on Sleep and Disease
This study will investigate the biological mechanisms linking sleep disruption by vibration and noise, and the development of cardiometabolic disease.
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- BioVib (NCT06260254)
- Testing
- Railway noise, Low level railway vibration, Intermediate level railway vibration
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Post-traumatic Stress Disorder (PTSD)
Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion
Brief Summary The goal of this clinical trial is to evaluate the feasibility and acceptability of a blended (mHealth) Trauma-Focused Cognitive Behavioral Therapy with Compassion (bTF-CBT-C) for adolescents with post-traumatic…
- Trial name
- b-TF-CBT-C (NCT07407946)
- Testing
- Blended Trauma-Focused Cognitive Behavioral Therapy with Compassion (bTF-CBT-C), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Umeå University
Liver Transplant; Complications, Immunosuppression
Effect of Cognitive Therapy on Immunosuppressive Treatment Compliance and Motivation
The study aims to analyze the effects of Mindfulness-Based Cognitive Therapy (MBCT) on the motivation levels and compliance with immunosuppressive therapy of post-liver transplant recipients.
- Conditions
- Liver Transplant; Complications, Immunosuppression, Compliance, Treatment
- Trial name
- NCT06879106
- Testing
- Intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Bitlis Eren University
Cognitive Impairment, Executive Dysfunction
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
Complaints about memory and thinking are common in women as they go through menopause and estrogen levels fall. The ovarian hormone estrogen is important for supporting normal cognitive function, and changes in brain activity and…
- Conditions
- Cognitive Impairment, Executive Dysfunction, Endothelial Dysfunction, Cardiovascular Disease
- Trial name
- NCT02122198
- Testing
- Leuprolide acetate, Estradiol, Medroxyprogesterone
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sedentary Time, Cognitive Function
Standing Desk Converter & Habitual Posture
This project will determine the short-term impact of a standing desk converter on: 1) objectively measured physical activity and posture levels, and 2) brain (cognition) and heart (blood pressure regulation) function.
- Conditions
- Sedentary Time, Cognitive Function, Blood Pressure Regulation
- Trial name
- NCT05970588
- Testing
- Standing Promotion Intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Olga Theou
Mild Cognitive Impairment, Caregiver Burden
A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI
This clinical trial is being conducted to see if brain stimulation and brain training together improves cognitive functioning and mood in older adults diagnosed with Mild Cognitive Impairment (MCI).
- Conditions
- Mild Cognitive Impairment, Caregiver Burden, Mental Health Issue, ADL
- Trial name
- rTMS+iVCT (NCT06024473)
- Testing
- rTMS, rTMS+iVCT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Arkansas Veterans Healthcare System
Aging
Do Ketone Drinks Improve Immune, Metabolic and Cognitive Health in Older Adults
The goal of this randomised, double-blinded, placebo-controlled trial is to investigate the immune, metabolic and cognitive effects of four weeks of daily ketone supplementation in adults aged 60 to 80 with stable health.
- Trial name
- NCT06068803
- Testing
- Ketone drink
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bath
Mental Health and General Well-being
The Influence of Mindfulness on the Link Between Consumer Culture Values and Well-being
The study is a three-arm intervention, where students are randomly assigned to one of three conditions: Teacher-led group-based MBCT, Self-guided MBCT using an audio book, or 'wait list' control.
- Trial name
- NCT03079154
- Testing
- Teacher-led MBCT course, Self-guided MBCT course
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Major Depressive Disorder
Study of Technology-assisted Treatment of Adolescent Depression
The purpose of this study is to evaluate a computer-guided, telephone-based therapy for adolescent depression, delivered in a pediatric primary setting in the community.
- Trial name
- iTAD (NCT01582581)
- Testing
- Telephonic CBT, Wait List Control
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- iHope Network, Inc.
Healthy
The Effect of Synaquell™ in Contact Sport Athletes
This research is being done to investigate the dietary supplement, Synaquell (TM), for effects on brain function in youth contact sport athletes.
- Trial name
- NCT06104670
- Testing
- Synaquell(TM)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Malocclusion, Dementia
Oral Health for Healthy Cognitive Aging
Oral health is a critical factor of systemic health, although usually forgotten. A potential relation between cognitive deficits and oral diseases has been suggested.
- Trial name
- SOECS (NCT02986386)
- Testing
- Dental occlusion restoration, Orthodontic treatment of malocclusion
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universidad de Granada
Cognitive Impairment, Mild, Dementia, Mild
Buddy-Up Dyadic Physical Activity Program for Persons With Dementia and Family Caregivers
The global cost of dementia is over 818 billion, and a further rise is expected in the next decade. While family caregiving is the backbone of the formal care service, promoting "living well with dementia" needs to extend to a…
- Conditions
- Cognitive Impairment, Mild, Dementia, Mild, Dementia, Caregiver Burden
- Trial name
- BUDPA (NCT06584110)
- Testing
- Buddy-Up Dyadic Physical Activity (BUDPA) program, Usual care with waitlist control
- Where
- Hong Kong
- Volunteers
- 236 people
- Sponsor
- The University of Hong Kong
Patients With Depression in the Elderly
The Construction and Application of a Mobile Health Management Program for Elderly Depression Based on the Patterns of Cognitive Function Changes
Based on the changing law of cognitive function, combined with the behavior change wheel theory and the health behavior process orientation model, we constructed a mobile health management program for geriatric depression.
- Trial name
- NCT06709027
- Testing
- Intervention Group (Mobile Health Management Intervention)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fujian Medical University
Diabetes Type 2, Diabetes Type 1
Disentangling the Effect of Brain Insulin Resistance on Brain Health
People with diabetes are at increased risk of developing dementia, including Alzheimer's disease and vascular dementia. In addition, persons with diabetes have more pronounced age-related brain atrophy and cognitive difficulties…
- Trial name
- BIR 1 (NCT07374705)
- Where
- 3 sites in Denmark, Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henrik Bo Wiberg Larsson
Quality of Life, Cognitive Decline
Health and Energy Through Active Living Every Day After Cancer Intervention for Cancer Survivors
The purpose of the Health and Energy through Active Living Every Day (HEALED) intervention, is to examine the effect of a web-based intervention on changes in device-measured physical activity (light and moderate-to-vigorous…
- Conditions
- Quality of Life, Cognitive Decline, Fatigue, Sleep
- Trial name
- HEALED (NCT05356988)
- Testing
- Physical activity experiment, Balance and flexibility control
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- American Cancer Society, Inc.
Lactose Intolerance
Effects Comparison of A1 and A2 Milk on Gastrointestinal Physiology, Symptoms and Cognitive Behavior
This is a single-site, double-blinded, randomized, controlled, 2X2 cross-over study aiming to compare effects of milk containing only A2 type beta casein versus milk containing both A1 and A2 beta casein proteins on the…
- Trial name
- NCT02406469
- Testing
- Oral consumption milk Tetra Pak
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.