Clinical trials: Cognitive Investigation
Nursing Students
Using Virtual Humans to Teach Cognitive Function Assessment to Nursing Students
Purpose of the Study This study wants to find out whether a virtual human (a computer-based simulated person) can help nursing students learn how to assess someone's thinking and memory skills.
- Trial name
- VHCT-NS (NCT07275372)
- Testing
- Virtual human, Printed material
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Dementia, Mild, Dementia of Alzheimer Type
Autonomic Involvement in Patient With Cognitive Decline
Prospective interventional study with a device for comparing autonomic parameters among patients with different forms of cognitive decline
- Trial name
- NCT06292741
- Testing
- Sudoscan
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cognitive Impairment, Preoperative Cognitive Impairment
Reliability In Neurocognitive Telemedicine Screening (RING)
Perioperative neurocognitive disorders are common after surgery and pre-existing cognitive impairment is an important risk factor.
- Conditions
- Cognitive Impairment, Preoperative Cognitive Impairment, Perioperative Neurocognitive Disorders, Neurocognitive Function
- Trial name
- NCT07760545
- Testing
- Modified Mini-Cog Telephone Assessment
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Mild Cognitive Impairment (MCI), Alzheimer Dementia (AD)
Predicting Pre-dementia
The goal of this observational study is to learn how well a multimodal "Progression and Risk" (PR) model can predict and stage early mild cognitive impairment (MCI) due to Alzheimer's disease in cognitively normal or very mildly…
- Conditions
- Mild Cognitive Impairment (MCI), Alzheimer Dementia (AD), Alzheimer Disease (AD), APOE-4 Positive
- Trial name
- NCT07516119
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prevention Research Consortium Corp.
Urinary Incontinence, Stress, Urinary Incontinence, Urge
French Study to Evaluate the Impact of a Cognitive Therapy on Urinary Incontinent Women of All Age's Perineal Settings.
This trial is a pathophysiological study evaluating the impact of a cognitive therapy on the perineal neuromuscular mechanisms in women patients with urinary incontinence.
- Trial name
- NCT03797365
- Testing
- Classical rehabilitation, Cognitive associated rehabilitation
- Volunteers
- 40 people
- Sponsor
- Pierre and Marie Curie University
Parkinson's Disease
A Multicenter Clinical Study of rTMS for Parkinson's Disease
Through rTMS, motor dysfunction and non-motor dysfunction of PD patients can be improved, working and living ability and quality of life of patients can be improved, and social burden and family burden can be reduced.
- Trial name
- NCT06009471
- Testing
- Routine treatment in Neurology, Routine treatment in Neurology and rTMS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Affiliated Hospital of Nantong University
Schizophrenia
Cognitive Behavioral Therapy Added to Risperidone for Schizophrenia
This study evaluated whether cognitive behavioral therapy (CBT), when added to risperidone treatment, improves cognitive function and serum brain-derived neurotrophic factor (BDNF) levels in patients with schizophrenia.
- Trial name
- CBT-BDNF-SCZ (NCT07609953)
- Testing
- Risperidone 4 to 6 mg/day, Cognitive Behavioral Therapy
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Hasanuddin University
Brain Injuries
A New Intervention for Social Communication Skills Following Brain Injury
To investigate the effectiveness of a peer-led social skills training intervention compared to social activity (usual care) to improve social communication skills following severe brain injury.
- Trial name
- NCT02211339
- Testing
- Peer facilitator training, Usual care
- Volunteers
- 12 people
- Sponsor
- University College, London
Mild Cognitive Impairment
Functional MRI Changes Resulting From the Feuerstein Program in Older People With Mild Cognitive Impairment (MCI)
Background: The Feuerstein Instrumental Enrichment Program was designed to prevent mental deterioration and preserve cognitive abilities among people aged 60 and above.
- Trial name
- NCT03447236
- Testing
- Feuerstein Program
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Rambam Health Care Campus
Coginitive Dysfunction
The Effects, Usability, Satisfaction, Barriers, and Benefits of a Remote, Multidomain Website-based Intervention to Prevent Cognitive Decline in Older Adults
Mexico exhibits a high prevalence of dementia, exceeding 8%, and it is estimated that by 2050 around 3.5 million older adults will be living with this condition.
- Trial name
- MeMoHealthCogR (NCT07668440)
- Testing
- Multi-domain intervention: Physical activity, cognitive training, and educational program through a website
- Where
- Mexico
- Volunteers
- 71 people
- Sponsor
- Instituto Mexicano del Seguro Social
Cardiovascular Diseases, Inflammation
Dietary Intake of Alpha-linolenic Acid in Elderly
The purpose of this study is to evaluate the antiatherogenic and anti-inflammatory potential of an adequate intake of alpha-linolenic acid in elderly.
- Conditions
- Cardiovascular Diseases, Inflammation, Metabolism Disorder, Lipid
- Trial name
- NCT03025620
- Testing
- Rapeseed oil, Sunflower oil
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alzheimer Disease, Mild Cognitive Impairment
Optina Diagnostics' Cerebral ß-Amyloid Status (CAS) Test
This observational, cross-sectional study is designed to validate a novel diagnostic test for the detection of phenotypic changes in the retina that correlate with likely PET amyloid status (negative or positive), to aid in the…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Mild Dementia
- Trial name
- REPHRASE (NCT05107882)
- Where
- 7 sites in United States, Canada
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Optina Diagnostics Inc.
B Thalassemia
Assessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates.
Multiple studies showed the negative impact thalassemia disease and its therapy have on the cognition of these patients. This study aims to assess and compare the cognition, psychological impact and quality of life among patients…
- Trial name
- NCT05105659
- Testing
- Wechsler IQ for Adults, MAS (Memory assessment scale), Health-Related Quality of Life (HRQoL)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Covid19, Sequelae of; Infection
Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
The study will assess whether Niagen, a safe dietary supplement, improves recovery of COVID-19 related symptoms in individuals who were infected at least 2 months prior to study entry ("Long-COVID" "Long-haulers").
- Conditions
- Covid19, Sequelae of; Infection, Cognitive Symptom
- Trial name
- NCT04809974
- Testing
- Niagen
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Rheumatic Diseases
Investigation From Biopsychosocial Perspective of Patients With Rheumatic Disease With Covid-19 Who Participated in a Biopsychosocial Exercise Program: A Case Series With 6-Month Follow-up
Objective: This novel study aimed to interrogate from a biopsychosocial perspective the health conditions during the Covid-19 infection and long-Covid periods of 5 patients with rheumatic disease infected with Covid-19 who had…
- Trial name
- NCT05787340
- Testing
- Bilişsel Egzersiz Terapi Yaklaşımı (BETY, Cognitive Exercise Therapy Approach)
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Mild Dementia
The Efficacy and Safety of tDCS in Patients With Mild Dementia
This study evaluated the effectiveness and safety of improving Mild Dementia by applying tDCS for 26 weeks to patients with Mild Dementia.
- Trial name
- NCT05495113
- Testing
- YMS-201B (Device: Mind STIM)
- Where
- 2 sites in South Korea
- Volunteers
- 118 people
- Sponsor
- Ybrain Inc.
Post Traumatic Stress Disorder
Online Mental Health Program for Female College Students
Late adolescence and early adulthood are the most exposed to trauma. College students exposed to trauma may experience depression, anxiety, stress, and difficulties adapting to college life.
- Trial name
- NCT04982523
- Testing
- Online Mental Health Program
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- CHA University
Major Depressive Disorder
Aripiprazole Augmentation of SSRI Therapy in Treatment Refractory Depression
Our target population will have been adequately treated with one of three selective serotonin reuptake inhibitors (SSRIs; escitalopram, citalopram, or sertraline) for at least 8-12 weeks and continue to experience symptoms of…
- Trial name
- NCT00608543
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Texas Southwestern Medical Center
Post COVID-19, Cognitive Dysfunction
Multimodal Investigation of Post COVID-19 in Females
The purpose of this study is to investigate the effects of transcutaneous vagus nerve stimulation (t-VNS) on Long Covid symptoms in females and to identify factors influencing susceptibility and recovery-particularly in the…
- Trial name
- NCT05225220
- Testing
- Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
HIV-1
Evaluation of a Short Version Computerized Test for Processing Speed to Detect Cognitive Disorders in HIV+ Patients
The objective of this prospective study is to evaluate the prevalence of neurocognitive impairments in HIV infected patients comparing patients with and without HAART.
- Trial name
- NEURACog (NCT03279835)
- Testing
- Classic evaluation of neurocognitive functions, New evaluation of neurocognitive functions
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
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