Clinical trials: Cognitive Investigation
Multiple Sclerosis, Long Covid
Fatigue Investigation Using Digital Outcomes
This study investigates objective methods to measure and monitor fatigue in patients with post-COVID-19 condition (long COVID) and multiple sclerosis (MS), and includes a group of healthy volunteers for comparison.
- Conditions
- Multiple Sclerosis, Long Covid, Healthy
- Trial name
- FIDO (NCT07783074)
- Where
- 6 sites in Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Liliana Barrios
Insomnia, Sleep Disorder
SleepUp Digital CBTi-based Platform for Insomnia
Cognitive-Behavioral Therapy for insomnia (CBTi) is a well-established therapeutic intervention for insomnia. SleepUp provides a digital therapeutics platform based on CBTi and additional features.
- Conditions
- Insomnia, Sleep Disorder, Sleep Hygiene
- Trial name
- NCT04949360
- Testing
- Online Cognitive-Behavioral Therapy for Insomnia and complementary therapies, Regular Cognitive Behavioural Therapy for Insomnia, Sleep hygiene - minimal intervention
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- SleepUp Tecnologia em Saúde Ltda
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Cognitive Change, Mood
Turmeric for Memory Impairment and Cognition
The objective of the study is to test the capacity of acute and chronic supplementations of Turmipure GOLD® to improve cognitive performance in healthy aging
- Conditions
- Cognitive Change, Mood, Stress
- Trial name
- TURMEMIC (NCT04860050)
- Testing
- Turmipure Gold®
- Where
- Ireland
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Bariatric Surgery Candidate, Obesity
A Preoperative Cognitive Behavioural Therapy Program Based on Self-determination Theory for Bariatric Surgery Candidates
The objective of this study is to evaluate the impact of a pre-surgical intervention program based on Cognitive and Behavioural Emotional Therapies, on the degree of dietary restriction of patients who are candidates for…
- Trial name
- ACRoBAT (NCT03976674)
- Testing
- Cognitive Behavioural Therapy (CBT)
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Lille Catholic University
Quality of Life, Aortic Valve Stenosis
Frailty and Cognitive Function Assessment of TAVI Patients
Aortic stenosis (AS) is the most common valve disease among the adult population, in the majority of the cases it only requires treatment in advanced age.
- Conditions
- Quality of Life, Aortic Valve Stenosis, Heart Valve Disease
- Trial name
- NCT02650388
- Testing
- Cognitive fuction, quality of life
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Hungarian Institute of Cardiology
Consciousness Disorder, Cognitive Impairment
Neurophysiological Evaluation of Residual Cognitive Functions in Patients With Severe Alterations of Consciousness
Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness.
- Trial name
- NCT05802524
- Testing
- Neurowave Group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Alzheimer's Disease
Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02)
Subjects will be adults aged 50 to 85 years who have subjective memory complaints and mild cognitive impairment or mild dementia due to Alzheimer's disease (AD).
- Trial name
- NCT01600859
- Testing
- E2609
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Eisai Inc.
Schizophrenia
Neurophysiological Evaluation of Schizophrenia Patients After Cognitive and Physical Intervention
Neurophysilogical, neuropsychological evaluation and cognitive and physical training
- Trial name
- NCT03899662
- Testing
- Cognitive Training, Physical Training
- Where
- Greece
- Volunteers
- 4 people
- Sponsor
- Aristotle University Of Thessaloniki
Obesity Hypoventilation Syndrome (OHS)
Functional Capacity, Sleep Quality, and Cognitive Function in Obesity Hypoventilation Syndrome
Introduction: Obesity Hypoventilation Syndrome (OHS) is defined as the coexistence of obesity (BMI ≥ 30 kg/m²), daytime hypercapnia (PaCO₂ > 45 mmHg) in the absence of other causes of hypoventilation, and sleep-disordered…
- Trial name
- NCT07147153
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Bezmialem Vakif University
IBS - Irritable Bowel Syndrome
Zemedy Application for Irritable Bowel Syndrome
The purpose of the study is investigate the effectiveness of Zemedy, a mobile application that enables the digital delivery of a CBT program to people with IBS.
- Trial name
- NCT04723056
- Testing
- Use of Zemedy Application
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Stanford University
Sensory Science, Performance Assessment
Personalized Performance Optimization Platform
Crews of future long-duration exploration missions will have to cope with a wide range of stressors that present significant challenges for maintaining optimal performance.
- Conditions
- Sensory Science, Performance Assessment, Countermeasure Evaluation, Neurocognitive Function
- Trial name
- P-POP (NCT06979570)
- Testing
- AttentivU
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alcoholism
Individualized Assessment and Treatment for Alcoholism II
The object of this study is to develop a treatment for alcohol use disorders that is more effective than current CB treatments. Through a 2009 R-21 pilot project the investigators developed a cognitive-behavioral (CB) treatment…
- Trial name
- IATP2 (NCT03233802)
- Testing
- Individualized Assess & Treatment (IATP), Packaged Cognitive-Behavioral (PCBT), Case Management (CaseM)
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- UConn Health
Attention Deficit Disorder With or Without Hyperactivity (ADHD)
Evaluating Effects of Group-based CBT for Emotion Regulation in Adult ADHD
This study will evaluate if a specific treatment for emotion regulation in ADHD, GEARS, effectively reduces symptoms of emotional dysregulation.
- Trial name
- GEARS (NCT07614867)
- Testing
- Group Therapy for Improving Emotional Acceptance and Regulatory Skills in Adults with ADHD (GEARS)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska Institutet
Insomnia
Health enSuite Insomnia: an App-based Treatment for Adult Chronic Insomnia
This project consists of a randomized controlled trial. The objective of this trial is to test the effectiveness of an app-based cognitive behavioral program for insomnia (Health enSuite: Insomnia) in reducing insomnia symptoms.
- Trial name
- NCT04962087
- Testing
- Experimental: Health enSuite Insomnia
- Where
- Canada
- Volunteers
- 415 people
- Sponsor
- IWK Health Centre
Neurodegenerative Diseases, Stroke
The Role of Humanoid Robot in Neuropsychological Assessment and Cognitive Training.
The role of humanoid robot in neuropsychological assessment and conducting cognitive training in patients with dementia and severe brain injury" Objectives Use of robotic solutions to carry out diagnostic and rehabilitation…
- Trial name
- NCT05788133
- Testing
- treatment and screening by neuropsychological tests on humanoid robot
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Alzheimer's Disease, Dementia
Study to Evaluate the Efficacy and Safety of ATNC-MDD V1(TMS With Cognitive Training) in Mild Alzheimer's Dementia
The study tests the effect of the ATNC MDD-V1 on Alzheimer patients' cognitive function. The ATNC MDD-V1 uses non-invasive stimulation of both magnetic and cognitive training.
- Conditions
- Alzheimer's Disease, Dementia, Brain Diseases, Central Nervous System Diseases
- Trial name
- ATC-P001 (NCT06088121)
- Testing
- ATNC MDD-V1 (Real TMS + Real Cog), ATNC BN-V1, ATNC BN-V2
- Where
- 11 sites in South Korea
- Volunteers
- 180 people
- Sponsor
- Advanced Technology & Communications
Depressive Symptoms, Anxiety
Feasibility Evaluation of a Monitored Self-guided Cognitive Behavioural Therapy Digital Format
The purpose of the study is to evaluate the feasibility of a new monitored self-guided digital cognitive behavioural therapy format through one of the key components of an intervention for depression and anxiety (Problem Solving)…
- Trial name
- NCT04277793
- Testing
- Monitored self-guided problem solving
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Sexual Function, Cognitive Functions
A Clinical Trial to Evaluate the Efficacy of a Men's Supplement in Supporting Testosterone, Improving Cognitive Function, Mood, and Sexual Function
This randomized, triple-blind, placebo-controlled, hybrid trial aims to evaluate the efficacy of a men's supplement designed to increase testosterone levels and improve energy, cognition, and sexual function.
- Conditions
- Sexual Function, Cognitive Functions, Testosterone
- Trial name
- NCT06596928
- Testing
- Essential Elements T-Hero Platinum
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Scale Media Inc
Aging, Mild Cognitive Impairment
Internet-based Conversational Engagement Clinical Trial
The study aims to randomize 320 (160 Caucasian, 160 African American) socially isolated adults 75+ years old (50:50 split between those with normal cognition and mild cognitive impairment (MCI)) recruited from the community to…
- Trial name
- I-CONECT (NCT02871921)
- Testing
- Conversational Engagement
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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